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Islet Cell Autoantigen 1, 69kDa (ICA1) ELISA Kits

ICA1 encodes a protein with an arfaptin homology domain that is found both in the cytosol and as membrane-bound form on the Golgi complex and immature secretory granules. Additionally we are shipping Islet Cell Autoantigen 1, 69kDa Antibodies (88) and Islet Cell Autoantigen 1, 69kDa Proteins (12) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
ICA1 15893 P97411
ICA1 81024  
ICA1 3382 Q05084
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Top Islet Cell Autoantigen 1, 69kDa ELISA Kits at antibodies-online.com

Showing 4 out of 9 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Delivery Price Details
Human 0.068 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests 13 to 16 Days
$736.84
Details
Mouse < 46.9 pg/mL 78 pg/mL - 5000 pg/mL   96 Tests 11 to 18 Days
$838.60
Details
Rat < 0.094 ng/mL 0.156 ng/mL - 10 ng/mL   96 Tests 11 to 18 Days
$838.60
Details
Human < 0.062 ng/mL 0.156 ng/mL - 10 ng/mL   96 Tests 11 to 18 Days
$902.56
Details

More ELISA Kits for Islet Cell Autoantigen 1, 69kDa Interaction Partners

Mouse (Murine) Islet Cell Autoantigen 1, 69kDa (ICA1) interaction partners

  1. The findings of this study indicated that ICA69 mediates the antihyperalgesic effects of EA on CFA-induced inflammatory pain by regulating spinal GluR2 through PICK1 in mice

  2. ICA69 deficiency promoted formalin-induced long-lasting pain hypersensitivity.

  3. direct link between compromised thymic ICA69 expression and autoimmunity against multiple ICA69-expressing organs, and identify a potential novel mechanism for the development of multi-organ autoimmune diseases.

  4. C-terminal domain of ICA69 interacts with PICK1 and acts on trafficking of PICK1-PKCalpha complex and cerebellar plasticity.

  5. PICK1 and ICA69 are key regulators of the formation and maturation of insulin granules.

  6. polymorphisms within the NOD Ica1 core promoter may determine AIRE-mediated down-regulation of ICA69 expression in medullary thymic epithelial cells.

  7. ICA69(null) nonobese diabetic mice develop diabetes, but resist disease acceleration by cyclophosphamide

Human Islet Cell Autoantigen 1, 69kDa (ICA1) interaction partners

  1. C-terminal domain of ICA69 interacts with PICK1 and acts on trafficking of PICK1-PKCalpha complex and cerebellar plasticity.

  2. Novel association was found between intraocular pressure and a common variant at 7p21 near to GLCCI1 and ICA1.

  3. polymorphisms within the NOD Ica1 core promoter may determine AIRE-mediated down-regulation of ICA69 expression in medullary thymic epithelial cells.

  4. The exon A promoter exhibits greater activity in islet cells, whereas the exon B promoter more efficiently activates transcription in neuronal cells.

  5. ICA69 as a novel Rab2 effector and its role in regulating the early transport of insulin secretory granule proteins

Islet Cell Autoantigen 1, 69kDa (ICA1) Antigen Profile

Antigen Summary

This gene encodes a protein with an arfaptin homology domain that is found both in the cytosol and as membrane-bound form on the Golgi complex and immature secretory granules. This protein is believed to be an autoantigen in insulin-dependent diabetes mellitus and primary Sjogren's syndrome. Several transcript variants encoding two different isoforms have been found for this gene.

Gene names and symbols associated with ICA1

  • islet cell autoantigen 1 L homeolog (ica1.L) antibody
  • islet cell autoantigen 1 (ICA1) antibody
  • islet cell autoantigen 1 (ica1) antibody
  • Islet cell autoantigen 1 (ica69) antibody
  • islet cell autoantigen 1 (Ica1) antibody
  • islet cell autoantigen 1 S homeolog (ica1.S) antibody
  • 69kDa antibody
  • DKFZp469G0321 antibody
  • ICA1 antibody
  • Ica69 antibody
  • ICAp69 antibody
  • MGC52730 antibody
  • MGC83241 antibody
  • zgc:92566 antibody

Protein level used designations for ICA1

islet cell autoantigen 1, 69kDa , Islet cell autoantigen 1 , islet cell autoantigen 1-like , 69 kDa islet cell autoantigen , ICAp69 , islet cell autoantigen 1, 69 kDa , islet cell autoantigen p69 , p69 , diabetes mellitus type I autoantigen , islet cell autoantigen 1 , islet cell autoantigen 1 isoform

GENE ID SPECIES
379786 Xenopus laevis
463264 Pan troglodytes
549616 Xenopus (Silurana) tropicalis
695889 Macaca mulatta
100171501 Pongo abelii
100380590 Salmo salar
100402491 Callithrix jacchus
100511342 Sus scrofa
100585518 Nomascus leucogenys
437003 Danio rerio
15893 Mus musculus
81024 Rattus norvegicus
414587 Xenopus laevis
420581 Gallus gallus
3382 Homo sapiens
475242 Canis lupus familiaris
535346 Bos taurus
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