Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
The sarcoplasmic reticulum (SR) is an intracellular membrane compartment that controls intracellular calcium concentration and therefore plays a role in excitation-contraction coupling. Additionally we are shipping Junctional Sarcoplasmic Reticulum Protein 1 Antibodies (9) and Junctional Sarcoplasmic Reticulum Protein 1 Proteins (6) and many more products for this protein.
Showing 3 out of 5 products:
Calcium entry activated by ablation of both JP45-CASQ1 and JP45-CASQ2 complexes supports tetanic force development in slow twitch soleus muscles.
Ca(2+) transients evoked by tetanic stimulation are the result of massive Ca(2+) influx due to enhanced Ca(v)1.1 channel activity, which restores muscle strength in JP45/CASQ1 double knockout mice.
cloning, developmental expression, localization in sarcoplasmic reticulum, interaction with alpha 1.1 voltage-gated calcium channel, and involvement in skeletal muscle excitation-contraction coupling
One of the molecules involved in the development or maintenance of skeletal muscle strength.
Data indicate that the presence of either one of these JP-45 variants decreased the sensitivity of the dihydropyridine receptor DHPR to activation.
The results may be explained by a modulatory effect of JP-45 related to its reported in vitro interaction with the dihydropyridine receptor and the SR Ca(2+) binding protein calsequestrin (CSQ).
The protein encoded by this gene is involved in excitation-contraction coupling at the sarcoplasmic reticulum. The encoded protein can interact with CACNA1S, CACNB1, and calsequestrin to help regulate calcium influx and efflux in skeletal muscle.
junctional sarcoplasmic reticulum protein 1
, junctional-face membrane protein of 45 kDa homolog
, homolog of mouse skeletal muscle sarcoplasmic reticulum protein JP-45
, skeletal muscle sarcoplasmic reticulum protein JP-45