anti-KH-Type Splicing Regulatory Protein (KHSRP) Antibodies

The KHSRP gene encodes a multifunctional RNA-binding protein implicated in a variety of cellular processes, including transcription, alternative pre-mRNA splicing, and mRNA localization (Min et al., 1997 [PubMed 9136930]\; Gherzi et al., 2004 [PubMed 15175153]).[supplied by OMIM, Apr 2010].. Additionally we are shipping KHSRP Kits (8) and KHSRP Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
KHSRP 8570 Q92945
KHSRP 16549 Q3U0V1
KHSRP 171137 Q99PF5
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Top anti-KHSRP Antibodies at antibodies-online.com

Showing 10 out of 67 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-KHSRP Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:1562500  Positive Control:  293T cell lysate KHSRP is strongly supported by BioGPS gene expression data to be expressed in Human HEK293T cells Rabbit Anti-KHSRP Antibody   Paraffin Embedded Tissue: Human Heart cell Cellular Data: cardiac cell of renal tubule Antibody Concentration: 4.0-8.0 ug/ml Magnification: 400X 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated IHC, WB Host:  Rabbit  Target Name:  KHSRP  Sample Type:  Thyroid Tumor lysates  Antibody Dilution:  1.0ug/ml WB Suggested Anti-KHSRP antibody Titration: 1 ug/mL Sample Type: Human heart 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (fro), IHC (p), IP, SimWes, WB Simple Western: KHSRP Antibody [NBP1-18910] - Simple Western lane view shows a specific band for KHSRP in 0.5 mg/ml of HeLa lysate. This experiment was performed under reducing conditions using the 12-230 kDa separation system. 0.1 mL Log in to see 7 to 9 Days
$556.31
Details
Human Rabbit Un-conjugated IF, IHC (p), WB Western blot analysis of KHSRP Antibody (N-term) (ABIN390852) in T47D cell line lysates (35 µg/lane). KHSRP (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human brain with KHSRP Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$335.50
Details
Bat Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of KHSRP Antibody (N-term) in T47D cell line lysates (35ug/lane). KHSRP (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated IF, IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to KHSRP on formalin-fixed paraffin-embedded human liver. [antibody concentration 3 ug/ml] Detection limit for recombinant GST tagged KHSRP is approximately 0.3ng/ml as a capture antibody. 100 μg Log in to see 11 to 12 Days
$440.00
Details
Human Mouse Un-conjugated IF, ELISA, WB Detection limit for recombinant GST tagged KHSRP is approximately 0.1ng/ml as a capture antibody. Immunofluorescence of monoclonal antibody to KHSRP on HeLa cell. [antibody concentration 10 ug/ml] 100 μg Log in to see 11 to 12 Days
$440.00
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), IP Immunohistochemistry-Paraffin: KHSRP Antibody [NBP1-18911] - Human breast carcinoma. Antibody used at a dilution of 1:1,000. 100 μL Log in to see 7 to 9 Days
$556.31
Details
Human Rabbit Un-conjugated IF, IHC (p), WB Western Blot at 1:1000 dilution + HepG2 whole cell lysate Lysates/proteins at 20 ug per lane. KHSRP Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL Log in to see 2 to 3 Days
$515.63
Details

KHSRP Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-KHSRP Antibodies

  1. Human Polyclonal KHSRP Primary Antibody for ICC, IF - ABIN438746 : Zhou, Gong, Eischeid, Chen: miR-27b targets KSRP to coordinate TLR4-mediated epithelial defense against Cryptosporidium parvum infection. in PLoS pathogens 2012 (PubMed)
    Show all 5 Pubmed References

  2. Human Polyclonal KHSRP Primary Antibody for ELISA, WB - ABIN563702 : Xu, McCarrey, Hecht: A cytoplasmic variant of the KH-type splicing regulatory protein serves as a decay-promoting factor for phosphoglycerate kinase 2 mRNA in murine male germ cells. in Nucleic acids research 2008 (PubMed)
    Show all 2 Pubmed References

  3. Cow (Bovine) Polyclonal KHSRP Primary Antibody for IHC, WB - ABIN2778858 : Ahn, Hwang, Liu, Wang, Zhang, Stephenson, Boronina, Cole, Dinkova-Kostova, Talalay, Cole: Electrophilic tuning of the chemoprotective natural product sulforaphane. in Proceedings of the National Academy of Sciences of the United States of America 2010 (PubMed)

More Antibodies against KHSRP Interaction Partners

Human KH-Type Splicing Regulatory Protein (KHSRP) interaction partners

  1. The authors find that KHSRP associates with the regulatory domain of RIG-I (show DDX58 Antibodies) to maintain the receptor in an inactive state and attenuate its sensing of viral RNA (vRNA).

  2. we discovered a novel mechanism underlying SUMOylation of KHSRP regulating the production of some special miRNAs.

  3. KSRP decreased EGR3 (show EGR3 Antibodies) mRNA stability in an ARE-independent manner.

  4. TGF-beta (show TGFB1 Antibodies)-induced KHSRP silencing is central in a pathway leading to gene-expression.

  5. mechanistic evidence that KSRP promotes the down-regulation of Spry4 (show SPRY4 Antibodies) by a previously unidentified mechanism, i.e. post-transcriptional mRNA regulation.

  6. The interaction between the KLHL12 (show KLHL12 Antibodies) and the C-terminal domain of KHSRP contributed to KHSRP ubiquitination, leading to downregulation of enterovirus internal ribosome entry sites-mediated translation in infected cells.

  7. The miRNA biogenesis factors, DDX17 (show DDX17 Antibodies) and KHSRP, regulate the protein level of Ago2 (show EIF2C2 Antibodies) in human cells.

  8. Results show that KHSRP protein is highly expressed in osteosarcoma cells and provide evidence for its important roles in regulatory controls of osteosarcoma pathogenesis.

  9. High FBP2 expression is associated with doxorubicin resistance in breast cancer .

  10. Further analyses indicated that KHSRP was involved in miR-26a maturation and inhibited the expression of PTEN in small cell lung cancer cells

Mouse (Murine) KH-Type Splicing Regulatory Protein (KHSRP) interaction partners

  1. Report KSRP/mRNA/microRNA interactions in chromatoid body of spermatids regulating spermatogenesis.

  2. CXCL-2 (show CXCL2 Antibodies) and HMOX-1 (show HMOX1 Antibodies) were upregulated in H. pylori infection after KSRP overexpression. This difference in expression of these genes implicated that KSRP was closely associated with and directly participated in the innate immune response against H. pylori.

  3. IFN-gamma (show IFNG Antibodies) production was increased in spleen cells of KSRP(-/-) mice.

  4. Resveratrol causes a shift from the mesenchymal-specific forms of these factors to the respective epithelial forms and increases the expression of the RNA-binding proteins KHSRP and hnRNPA1 (show HNRNPA1 Antibodies).

  5. KSRP is critical in governing hepatic lipid metabolism through controlling Per2 (show PER2 Antibodies) expression

  6. KSRP modulation of GAP-43 (show GAP43 Antibodies) mRNA stability restricts axonal outgrowth in embryonic hippocampal neurons.

  7. This study reveals the in vivo function of KSRP in controlling brown-like transformation of subcutaneous/inguinal white adipose tissue through post-transcriptional regulation of miR (show MLXIP Antibodies)-150 expression.

  8. This study reveals a novel in vivo function of KSRP in controlling adipose lipolysis through posttranscriptional regulation of miR (show MLXIP Antibodies)-145 expression.

  9. KSRP is required to maintain P19 cells in undifferentiated state and that its inactivation can orient cells towards neural differentiation.

  10. Our results outline a critical role for KSRP in regulating pro-inflammatory mediators and have implications for a wide range of CNS inflammatory and autoimmune diseases.

KHSRP Antigen Profile

Protein Summary

The KHSRP gene encodes a multifunctional RNA-binding protein implicated in a variety of cellular processes, including transcription, alternative pre-mRNA splicing, and mRNA localization (Min et al., 1997

Gene names and symbols associated with KHSRP

  • KH-type splicing regulatory protein (KHSRP) antibody
  • KH-type splicing regulatory protein L homeolog (khsrp.L) antibody
  • KH-type splicing regulatory protein (khsrp) antibody
  • KH-type splicing regulatory protein (Khsrp) antibody
  • 6330409F21Rik antibody
  • Fbp2 antibody
  • fc94c12 antibody
  • Fubp2 antibody
  • KHSRP antibody
  • Ksrp antibody
  • Marta1 antibody
  • VgRBP71 antibody
  • wu:fb25b12 antibody
  • wu:fc10e10 antibody
  • wu:fc94c12 antibody
  • zgc:163038 antibody

Protein level used designations for KHSRP

KH-type splicing regulatory protein , KH-type splicing regulatory protein (FUSE binding protein 2) , FUSE binding protein 2 , far upstream element-binding protein 2 , fc10e10 , FUSE-binding protein 2 , KH type-splicing regulatory protein , p75 , KSRP , MAP2 RNA trans-acting protein 1 , MAP2 RNA trans-acting protein MARTA1 , zipcode-binding protein 2

GENE ID SPECIES
455640 Pan troglodytes
485022 Canis lupus familiaris
702544 Macaca mulatta
100158419 Xenopus laevis
100170586 Xenopus (Silurana) tropicalis
100356263 Oryctolagus cuniculus
573145 Danio rerio
100065608 Equus caballus
8570 Homo sapiens
16549 Mus musculus
171137 Rattus norvegicus
374140 Gallus gallus
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