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KIAA0319L is a candidate gene for dyslexia susceptibility.[provided by RefSeq, Apr 2009].. Additionally we are shipping KIAA0319L Proteins (5) and many more products for this protein.
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Analyses of Kiaa0319L (AU040320) and double Kiaa0319;AU040320 knockouts (dKO) revealed no evidence for impaired cortical lamination, neuronal migration, neurogenesis or other anatomical abnormalities. However, dKO mice displayed an auditory deficit in a behavioral gap-in-noise detection task. Recordings of click-evoked auditory brainstem responses revealed suprathreshold deficits in wave III amplitude in AU040320-KO mice.
genetic ablation of AAVR renders a wide range of mammalian cell types highly resistant to AAV2 infection
Optic nerve damage may change retinal architecture to allow greater penetration of an AAV2 virus to transduce several additional cell types in the inner nuclear layer.
AAVR directly binds to AAV2 particles, and that anti-AAVR antibodies efficiently block AAV2 infection; moreover, genetic ablation of AAVR renders a wide range of mammalian cell types highly resistant to AAV2 infection
genetic association study in Han population in China: Data suggest an SNP in PXK [rs2176082(C/T); but not rs6445975(G/T)] is associated with recurrent pregnancy loss; SNPs in KIAA0319L [rs2275247(A/G)] or JAZF1 [rs1635852(C/T)] are not associated.
Results identify KIAA0319L as novel susceptibility loci for Systemic sclerosis (SSc) and systemic lupus erythematosus (SLE). KIAA0319L was overexpressed in peripheral blood cells of SSc and SLE patients compared with healthy controls.
Kiaa0319-like protein interacts with Nogo Receptor 1, supporting the idea that Kiaa0319-like protein participates in axon guidance.
KIAA0319L remains an intriguing positional and functional candidate for RD, especially when considered alongside the supporting evidence for its homolog KIAA0319 on chromosome 6p.
This gene is a candidate gene for dyslexia susceptibility.
, dyslexia-associated protein KIAA0319-like protein
, likely ortholog of H. sapiens polycystic kidney disease 1-like (PKD1-like)
, polycystic kidney disease 1-like
, polycystic kidney disease 1-related