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KIAA0430 encodes a putative peroxisomal protein that appears to be conserved across Euteleostomi. Additionally we are shipping and many more products for this protein.
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Human MARF1 is an endoribonuclease that interacts with the DCP1:DCP2 decapping complex and degrades target mRNAs.
LMKB is the first protein identified to date that interacts with this portion of Ge-1. LMKB was expressed in human B and T lymphocyte cell lines; depletion of LMKB increased expression of IFI44L.
Purified MARF1 cleaved ssRNAs in vitro.
Here, the authors report that meiosis arrest female 1 (MARF1) is an RBP that is expressed during neuronal differentiation. Cortical neurons expressed the somatic form of MARF1 (sMARF1) but not the oocyte form (oMARF1). sMARF1 was enriched in embryonic brains, and its expression level decreased as brain development progressed.
Meiosis arrest female 1 (MARF1) has nuage-like function in mammalian oocytes.
MARF1 (4921513D23Rik), by suppressing levels of specific transcripts, is an essential regulator of important oogenic processes leading to female fertility and the development of healthy offspring
This gene encodes a putative peroxisomal protein that appears to be conserved across Euteleostomi. In humans, it may be autoantigenic.
, meiosis arrest female 1
, meiosis arrest female protein 1
, protein phosphatase 1, regulatory subunit 34