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KRT10 encodes a member of the type I (acidic) cytokeratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Additionally we are shipping Keratin 10 Kits (19) and Keratin 10 Proteins (8) and many more products for this protein.
Showing 10 out of 383 products:
Human Monoclonal KRT10 Primary Antibody for ICC, FACS - ABIN335328
Broers, Carney, Klein Rot, Schaart, Lane, Vooijs, Ramaekers: Intermediate filament proteins in classic and variant types of small cell lung carcinoma cell lines: a biochemical and immunochemical analysis using a panel of monoclonal and polyclonal antibodies. in Journal of cell science 1987
Show all 12 Pubmed References
Human Monoclonal KRT10 Primary Antibody for ICC, FACS - ABIN335337
Ivanyi, Ansink, Groeneveld, Hageman, Mooi, Heintz: New monoclonal antibodies recognizing epidermal differentiation-associated keratins in formalin-fixed, paraffin-embedded tissue. Keratin 10 expression in carcinoma of the vulva. in The Journal of pathology 1989
Show all 9 Pubmed References
Human Monoclonal KRT10 Primary Antibody for ICC, IHC (p) - ABIN1301947
Ivanyi, Minke, Hageman, Groeneveld, van Doornewaard: Patterns of expression of feline cytokeratins in healthy epithelia and mammary carcinoma cells. in American journal of veterinary research 1992
Human Polyclonal KRT10 Primary Antibody for IF (p), IHC (p) - ABIN1387866
Li, Yang, Cai, Wang, Tian, Huang, Qiang, Zhang, Li, Li, Jiang: Oil Body-Bound Oleosin-rhFGF-10: A Novel Drug Delivery System that Improves Skin Penetration to Accelerate Wound Healing and Hair Growth in Mice. in International journal of molecular sciences 2017
Cat (Feline) Monoclonal KRT10 Primary Antibody for IHC (fro), IHC (p) - ABIN114446
Ivanyi, Groeneveld, Van Doornewaard, Mooi, Hageman: Keratin subtypes in carcinomas of the uterine cervix: implications for histogenesis and differential diagnosis. in Cancer research 1990
Show all 4 Pubmed References
Cow (Bovine) Polyclonal KRT10 Primary Antibody for WB - ABIN2776960
Tsubota, Akiyama, Kanitakis, Sakai, Nomura, Claudy, Shimizu: Mild recessive bullous congenital ichthyosiform erythroderma due to a previously unidentified homozygous keratin 10 nonsense mutation. in The Journal of investigative dermatology 2008
Results show that missense mutations exert dominant negative effects on the keratins K1/K10 protein structure by altering inter-chain interactions.
KRT10 gene mutation was present in all of the affected individuals, but absent in the five unaffected and 100 ethnically-matched healthy controls.
Mutations in the highly conserved helix initiation motif of K10 were associated with mild or severe form of epidermolytic ichthyosis (show LBR Antibodies)
Case Report: post-zygotic mosaicism of KRT/1o mutations in epidermolytic Ichthyosis (show LBR Antibodies).
Report genetic/clinical spectrum of KRT10 mutations in keratinopathic ichthyosis (show LBR Antibodies).
We present an autosomal dominant pedigree with epidermolytic ichthyosis (show LBR Antibodies) resulting from a new heterozygous missense mutation in keratin 10.
Complete structure of an epithelial keratin 1/keratin 10 dimer has been presented.
recombinant adenovirus-mediated overexpression of KRT10 and PTEN may improve the cisplatin resistance of ovarian cancer in vitro and in vivo
findings provide structural insights into phenotypic variation in epidermolytic ichthyosis (show LBR Antibodies) due to KRT10 mutations
The diagnosis of ichthyosis (show LBR Antibodies) with confetti was confirmed by the identification of 2 previously unreported mutations in intron 6 and exon 7 of KRT10.
This study demonstrates that the loss of the main cytoskeletal components of plantar epidermis, i.e. K2 and K10, can be only partly compensated by the upregulation of other keratins.
The Krt1(-/-);Krt10(-/-) mice showed premature loss of nuclei during epidermal differentiation and lower levels of emerin (show EMD Antibodies), lamin A/C (show LMNA Antibodies) and Sun1 (show SUN1 Antibodies), revealing a previously unknown function for IFs in maintaining nuclear integrity in the upper epidermis.
Aging enhances susceptibility to pneumococcal pneumonia in a K10-dependent manner.
The epidermis of adult K10-/- mice displayed hyperproliferation of basal keratinocytes and increased cell size,accompanied by the induction of c-Myc (show MYC Antibodies), cyclin D1 (show CCND1 Antibodies), 14-3-3sigma and wound healing keratins K6 and K16 (show KRT16 Antibodies).
loss of a keratin, a cytoskeletal protein (show ADD3 Antibodies), reduces tumor formation
The absence of keratin 10 stimulates cell differentiation and proliferation in sebacous glands.
This gene encodes a member of the type I (acidic) cytokeratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. Mutations in this gene are associated with epidermolytic hyperkeratosis. This gene is located within a cluster of keratin family members on chromosome 17q21.
, keratin 9 (epidermolytic palmoplantar keratoderma)
, keratin 10 (epidermolytic hyperkeratosis; keratosis palmaris et plantaris)
, keratin 25D
, keratin, type I cytoskeletal 10
, cytokeratin 10
, cytokeratin VIB
, epidermolytic hyperkeratosis; keratosis palmaris et plantaris
, keratin 10 (epidermolytic hyperkeratosis)
, type I keratin KA10
, epithelial keratin 10
, epithelial keratin-10
, 56 kDa cytokeratin
, epidermal keratin 10
, intermediate filament protein
, keratin complex 1, acidic, gene 10
, keratin, type I cytoskeletal 59 kDa
, suprabasal cytokeratin 10