anti-Keratin 10 (KRT10) Antibodies

KRT10 encodes a member of the type I (acidic) cytokeratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Additionally we are shipping Keratin 10 Kits (11) and Keratin 10 Proteins (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
KRT10 3858 P13645
KRT10 16661 P02535
KRT10 450225 Q6IFW6
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Top anti-Keratin 10 Antibodies at

Showing 10 out of 412 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-KRT10 Antibody Titration:  0.2-1 ug/ml  Positive Control:  721_B cell lysate Host:  Mouse  Target Name:  KRT10  Sample Tissue:  Mouse Brain  Antibody Dilution:  1ug/ml 100 μL 2 to 3 Days
Dog Rabbit Un-conjugated IC, IF, IHC, WB Immunofluorescent analysis of Cytokeratin 10 staining in A431 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of Cytokeratin 10 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL 13 to 14 Days
Human Mouse Un-conjugated ICC, FACS, IHC (fro), IHC, WB 0.1 mg 5 to 7 Days
Cat Mouse Un-conjugated FACS, IHC (fro), IF, IHC (p), WB   0.1 mg 6 to 8 Days
Dog Mouse Un-conjugated FACS, ICC, IHC, IHC (fro), WB 0.1 mg 11 to 14 Days
Human Rabbit Un-conjugated IHC ABIN6383835 to KRT10 was successfully used to stain human skin sections. Recommended concentration: 0.1-0.3ug/ml; SDS-PAGE Analysis of Purified KRT10 Rabbit Recombinant Monoclonal Antibody ABIN6383835. Confirmation of Purity and Integrity of Antibody.; Integrity of the purified antibody ABIN6383835 under non-reduced and reduced conditions, showing intact IgG at around 120kDa (NR) and intact heavy and light chains at 50kDa and 25kDa resp. ® 100 μg 11 to 12 Days
Human Rabbit Un-conjugated IF, ELISA, WB Western blot analysis of extracts from HeLa cells, using Keratin 10 Antibody. The lane on the right is treated with the synthesized peptide. Immunofluorescence analysis of A549 cells, using Keratin 10 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg 2 to 3 Days
Dog Mouse Un-conjugated IHC (fro), FACS, IF, WB   0.1 mg 6 to 8 Days
Human Rabbit Un-conjugated ELISA, IF, IHC, WB Western Blot (WB) analysis of specific cells using Cytokeratin 10 Polyclonal Antibody. 100 μL Available
Human Rabbit Un-conjugated EIA, WB Western blot analysis of KRT10 antibody (Center) in CEM cell line lysates (35ug/lane). KRT10 (arrow) was detected using the purified Pab. 0.4 mL 6 to 8 Days

Top referenced anti-Keratin 10 Antibodies

  1. Human Monoclonal KRT10 Primary Antibody for ICC, FACS - ABIN335328 : Broers, Carney, Klein Rot, Schaart, Lane, Vooijs, Ramaekers: Intermediate filament proteins in classic and variant types of small cell lung carcinoma cell lines: a biochemical and immunochemical analysis using a panel of monoclonal and polyclonal antibodies. in Journal of cell science 1987 (PubMed)
    Show all 12 Pubmed References

  2. Human Monoclonal KRT10 Primary Antibody for ICC, FACS - ABIN335337 : Ivanyi, Ansink, Groeneveld, Hageman, Mooi, Heintz: New monoclonal antibodies recognizing epidermal differentiation-associated keratins in formalin-fixed, paraffin-embedded tissue. Keratin 10 expression in carcinoma of the vulva. in The Journal of pathology 1989 (PubMed)
    Show all 9 Pubmed References

  3. Human Polyclonal KRT10 Primary Antibody for IF (p), IHC (p) - ABIN1387866 : Li, Yang, Cai, Wang, Tian, Huang, Qiang, Zhang, Li, Li, Jiang: Oil Body-Bound Oleosin-rhFGF-10: A Novel Drug Delivery System that Improves Skin Penetration to Accelerate Wound Healing and Hair Growth in Mice. in International journal of molecular sciences 2017 (PubMed)
    Show all 2 Pubmed References

  4. Cow (Bovine) Polyclonal KRT10 Primary Antibody for WB - ABIN2776960 : Tsubota, Akiyama, Kanitakis, Sakai, Nomura, Claudy, Shimizu: Mild recessive bullous congenital ichthyosiform erythroderma due to a previously unidentified homozygous keratin 10 nonsense mutation. in The Journal of investigative dermatology 2008 (PubMed)

  5. Human Monoclonal KRT10 Primary Antibody for ICC, IHC (p) - ABIN1301947 : Ivanyi, Minke, Hageman, Groeneveld, van Doornewaard: Patterns of expression of feline cytokeratins in healthy epithelia and mammary carcinoma cells. in American journal of veterinary research 1992 (PubMed)

  6. Cat (Feline) Monoclonal KRT10 Primary Antibody for IHC (fro), IHC (p) - ABIN114446 : Ivanyi, Groeneveld, Van Doornewaard, Mooi, Hageman: Keratin subtypes in carcinomas of the uterine cervix: implications for histogenesis and differential diagnosis. in Cancer research 1990 (PubMed)
    Show all 4 Pubmed References

  7. Human Polyclonal KRT10 Primary Antibody for IHC, IHC (p) - ABIN4302299 : Kim, Lee, Lee, Ahn, Kim, Liu, Jin, Ha, Bae, Lee, Noh: Phosphodiesterase 4B plays a role in benzophenone-3-induced phototoxicity in normal human keratinocytes. in Toxicology and applied pharmacology 2018 (PubMed)

More Antibodies against Keratin 10 Interaction Partners

Human Keratin 10 (KRT10) interaction partners

  1. These findings indicate that alpha112:alpha556 (IV) network, which is the only network that includes the alpha6(IV) chain, is one regulator of KRT10 expression in keratinization of oral mucosal epithelium.

  2. Results showed identical expression pattern for KRT1 and KRT10, their expression was higher in pediatric cases than in adults, especially in pediatric recurrent samples.

  3. The molecular diagnostics by the whole exome sequencing showed a novel de novo (c.1374-2A>C) mutation in the KRT10 gene responsible for the development of IWC (KRT10 defect was confirmed by immunofluorescent study). Concurrently, the m.14484T>C mutation in mitochondrial MTND6 gene (characteristic for Leber's hereditary optic neuropathy or LHON) was detected in patient, his mother and brother

  4. Results show that missense mutations exert dominant negative effects on the keratins K1/K10 protein structure by altering inter-chain interactions.

  5. KRT10 gene mutation was present in all of the affected individuals, but absent in the five unaffected and 100 ethnically-matched healthy controls.

  6. Mutations in the highly conserved helix initiation motif of K10 were associated with mild or severe form of epidermolytic ichthyosis

  7. Case Report: post-zygotic mosaicism of KRT/1o mutations in epidermolytic Ichthyosis.

  8. Report genetic/clinical spectrum of KRT10 mutations in keratinopathic ichthyosis.

  9. We present an autosomal dominant pedigree with epidermolytic ichthyosis resulting from a new heterozygous missense mutation in keratin 10.

  10. Complete structure of an epithelial keratin 1/keratin 10 dimer has been presented.

  11. recombinant adenovirus-mediated overexpression of KRT10 and PTEN may improve the cisplatin resistance of ovarian cancer in vitro and in vivo

  12. findings provide structural insights into phenotypic variation in epidermolytic ichthyosis due to KRT10 mutations

  13. The diagnosis of ichthyosis with confetti was confirmed by the identification of 2 previously unreported mutations in intron 6 and exon 7 of KRT10.

  14. We present the spectrum of clinical variability of ichthyosis with confetti in 6 patients with confirmed mutations in KRT10.

  15. Case Report: extensive postzygotic mosaicism for a novel keratin 10 mutation in epidermolytic ichthyosis.

  16. Data indicate that KRT10 is a downstream molecule of PTEN which improves cisplatin-resistance of ovarian cancer cells.

  17. Most of the orthokeratotic dysplasia constituent cells were immunopositive for keratin 10, but not for keratins 13, 17 or 19.

  18. Among Japanese patients with bullous congenital ichthyosiform erythroderma for which genetic diagnosis was determined, all showed mustations in KRT1 or KRT10.

  19. Molecular mimicry between HSP 65 of Mycobacterium leprae and cytokeratin 10 of the host keratin play the role in pathogenesis of leprosy.

  20. Pneumococcal ligands K10, laminin receptor and platelet-activating factor receptor are elevated in aged lungs and contribute to the enhanced susceptibility to pneumonia.

Mouse (Murine) Keratin 10 (KRT10) interaction partners

  1. These findings indicate that alpha112:alpha556 (IV) network, which is the only network that includes the alpha6(IV) chain, is one regulator of KRT10 expression in keratinization of oral mucosal epithelium.

  2. This study demonstrates that the loss of the main cytoskeletal components of plantar epidermis, i.e. K2 and K10, can be only partly compensated by the upregulation of other keratins.

  3. The Krt1(-/-);Krt10(-/-) mice showed premature loss of nuclei during epidermal differentiation and lower levels of emerin, lamin A/C and Sun1, revealing a previously unknown function for IFs in maintaining nuclear integrity in the upper epidermis.

  4. Aging enhances susceptibility to pneumococcal pneumonia in a K10-dependent manner.

  5. expression in epidermal basal layer inhibits cell proliferation and prevents skin tumorigenesis

  6. The epidermis of adult K10-/- mice displayed hyperproliferation of basal keratinocytes and increased cell size,accompanied by the induction of c-Myc, cyclin D1, 14-3-3sigma and wound healing keratins K6 and K16.

  7. role in inducing severe abnormalities in oral mucosa

  8. loss of a keratin, a cytoskeletal protein, reduces tumor formation

  9. The absence of keratin 10 stimulates cell differentiation and proliferation in sebacous glands.

Keratin 10 (KRT10) Antigen Profile

Protein Summary

This gene encodes a member of the type I (acidic) cytokeratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. Mutations in this gene are associated with epidermolytic hyperkeratosis. This gene is located within a cluster of keratin family members on chromosome 17q21.

Gene names and symbols associated with anti-Keratin 10 (KRT10) Antibodies

  • keratin 10 (KRT10) antibody
  • keratin 10 (Krt10) antibody
  • keratin 10, type I S homeolog (krt10.S) antibody
  • keratin, type I cytoskeletal 25 (LOC101085587) antibody
  • BCIE antibody
  • BIE antibody
  • CK10 antibody
  • D130054E02Rik antibody
  • EHK antibody
  • K1C1 antibody
  • K10 antibody
  • Ka10 antibody
  • Ker10 antibody
  • KPP antibody
  • Krt-1.10 antibody
  • Krt1-10 antibody
  • KRT10 antibody
  • KRT25 antibody
  • KRT27 antibody
  • KRT28 antibody

Protein level used designations for anti-Keratin 10 (KRT10) Antibodies

CK-10 , cytokeratin 10 , keratin, type I cytoskeletal 10 , keratin-10 , 56 kDa cytokeratin , cytokeratin-10 , epidermal keratin 10 , intermediate filament protein , keratin complex 1, acidic, gene 10 , keratin, type I cytoskeletal 59 kDa , suprabasal cytokeratin 10 , K10 , cytokeratin VIB , cytokeratin-6B , epidermolytic hyperkeratosis; keratosis palmaris et plantaris , keratin 10 (epidermolytic hyperkeratosis) , keratin 10 (epidermolytic hyperkeratosis; keratosis palmaris et plantaris) , type I keratin KA10 , keratin 25D , epithelial keratin 10 , epithelial keratin-10 , keratin 10 , keratin 25 , keratin 27 , keratin 28 , keratin, type I cytoskeletal 25 , keratin, type I cytoskeletal 27

3858 Homo sapiens
16661 Mus musculus
281888 Bos taurus
450225 Rattus norvegicus
468240 Pan troglodytes
491006 Canis lupus familiaris
100009029 Oryctolagus cuniculus
100381074 Xenopus laevis
100470629 Ailuropoda melanoleuca
100519971 Sus scrofa
101085587 Felis catus
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