Keratin 14 Proteins (KRT14)

KRT14 encodes a member of the keratin family, the most diverse group of intermediate filaments. Additionally we are shipping Keratin 14 Antibodies (342) and Keratin 14 Kits (6) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
KRT14 3861 P02533
KRT14 16664 Q61781
KRT14 287701 Q6IFV1
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Top Keratin 14 Proteins at antibodies-online.com

Showing 10 out of 18 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$9,626.73
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$9,626.73
Details
Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 15 to 18 Days
$669.00
Details
Escherichia coli (E. coli) Mouse His tag,T7 tag 100 μg Log in to see 15 to 18 Days
$704.00
Details
Escherichia coli (E. coli) Rat His tag,T7 tag 100 μg Log in to see 15 to 18 Days
$752.00
Details
Escherichia coli (E. coli) Human His tag Validation with Western Blot 50 μg Log in to see 11 Days
$284.90
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Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$414.29
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Escherichia coli (E. coli) Human His tag 100 μg Log in to see 15 to 19 Days
$492.31
Details
Yeast Cow His tag   1 mg Log in to see 60 to 71 Days
$2,154.17
Details
Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 9 to 11 Days
$557.71
Details

KRT14 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine) ,
,
Rat (Rattus)

More Proteins for Keratin 14 (KRT14) Interaction Partners

Human Keratin 14 (KRT14) interaction partners

  1. High CK14 expression is associated with lymph node metastasis in oral squamous cell carcinoma.

  2. Efficient homology-directed repair of a dominant negative KRT14 mutation via CRISPR/Cas9 nickases in epidermolysis bullosa simplex patients' keratinocytes has been reported.

  3. Immunocytochemical staining using cocktail antibody targeting p63/CK14 was useful for the differential diagnosis of FA and DCIS in FNAC of the breast.

  4. the findings show that squamous and micropapillary bladder cancers have different expression patterns of CK14 and FOXA1 and suggest that they arise from distinct precursors.

  5. PADI4 contributes to gastric tumorigenesis by upregulating CXCR2, KRT14 and TNF-alpha expression.

  6. this study adds a further 10 novel mutations to the catalogued genotype-phenotype correlations in epidermolysis bullosa simplex and demonstrates a potential modifying effect of SNPs on the phenotype. We therefore support the notion of full DNA sequencing of both KRT5 and KRT14 genes so as to not miss any variants in the genes contributing to the phenotype.

  7. The novel c.1234A>G(p.Ile412Val) mutation of the KRT14 gene is probably responsible for the disease.

  8. Keratin14/p63-positive epithelial proliferations suggest benign breast disease.

  9. K14 was coexpressed with alphav-integrin in fetal and adult corneas and cultured corneolimbal epithelium, and colony-forming efficiency (an indicator of stem cell activity) was similar in cells from both sources.

  10. Loss of keratin 14 is associated with epidermolysis bullosa.

  11. contributes to collective invasion of salivary adenoid cystic carcinoma and may be a biomarker of worse prognosis

  12. vimentin regulates the differentiation switch via modulation of K5/K14 expression. Moreover, because there was a significant correlation between high vimentin-K14 expression and recurrence/poor survival in oral cancer patients, vimentin-K14 together may prove to be the novel markers for the prognostication of human oral cancer.

  13. We concluded that smoking habits were capable of inducing changes in global DNA methylation, miR-9-3 methylation status and K19 expression.

  14. data demonstrates that keratinocyte migration requires the interaction between vimentin and keratins at the -YRKLLEGEE- sequence at the helical 2B domain of viment

  15. Immunocytochemistry using this antibody cocktail comprises five antibodies recognising p63, and cytokeratins ( 7, 18, 5 and 14) showed good sensitivity and specificity for diagnosing breast cancers. Thus, this method is useful for mammary cytology using FNA

  16. identification of 29 different mutations in KRT5 and KRT14, 11 of which were novel, in a Polish cohort of epidermolysis bullosa simplex patients

  17. findings reveal K14 as a key regulator of metastasis and establish the concept that K14(+) epithelial tumor cell clusters disseminate collectively to colonize distant organs

  18. all keratins tested, except for keratin 14, were evenly expressed in all trophoblast cells. Keratin 14 was expressed in a subset of CK7 positive cells

  19. report a family with a novel heterozygous missense mutation p.Leu418Gln in the KRT14 gene causing epidermolysis bullosa simplex with variable phenotype

  20. investigated a family in which 1 of 3 children was diagnosed with a localized form of epidermolysis bullosa simplex and there was no family history of blistering; results argue against parental somatic and germline mosaicism in the family and suggest the novel p.Val270Ala mutation in KRT14 also represents a de novo event which occurred in the proband

Mouse (Murine) Keratin 14 (KRT14) interaction partners

  1. Cumulatively, these data indicate that altered CK14 (high) and CK18 (low) expression is perhaps an early event in bladder cancer tumorigenesis in females at least and is characteristic of both urothelial superficial pre-neoplastic and neoplastic lesions.

  2. KRT14 is expressed in a subpopulation of bladder basal cells with pivotal role in regeneration and tumorigenesis.

  3. CDK1, Aurora-B, and Rho-kinase phosphorylate keratin 5/14.

  4. RA regulates Krt5 and Krt14 expression independently of stem cell character in developing salivary epithelium. The stem cell gene Kit is regulated inversely from Krt5/Krt14 by RA signaling.

  5. Analysis of K14 variants with single or multiple substitutions of cysteine residues points to a spatial and temporal hierarchy in how Cys-4/Cys-40 and Cys-367 regulate keratin assembly in vitro and filament dynamics in live keratinocytes

  6. Disulfide bonding is a novel and important mechanism regulating the assembly, intracellular organization, and dynamics of K14-containing intermediate filaments in skin keratinocytes.

  7. K14-VEGF transgenic mouse a valuable model to study novel immunotherapies for psoriasis

  8. autoantibodies in Scurfy mice and patients with IPEX target keratin 14

  9. nipple connective tissue and its development: insights from the keratin 14-PTHrP mouse

  10. The keratin-14 IL-4 transgenic (Tg) mouse model of atopic dermatitis (AD) is characterized by skin infiltration of T cells, early up-regulation of T(h)2 cytokines and late surge of T(h)1 cytokines.

  11. These studies provide a potential mechanism by which deltaNp63 directly governs the expression of K14 in a keratinocyte-specific manner.

  12. Study describes the expression profile of claudins and keratin markers in the accelerated epidermal permeability barrier formation of K14-CaSR transgenic mice during development as compared to the wild type from E12.5 to newborn stages.

  13. IL-6 and IFN-gamma stimulated VEGF-A mRNA production in the skin and in primary keratinocytes of keratin 14 IL-4 transgenic mice

  14. DeltaNp63 alone can restore the expression of the basal keratins and reinitiate the failed epidermal differentiation program in the skin of p63 null animals.

Xenopus laevis Keratin 14 (KRT14) interaction partners

  1. findings indicate that ouro1 and ouro2 participate in the process of tail regression as immune antigens and highlight the possibility that the acquired immune system contributes not only to self-defense but also to remodeling processes in morphogenesis.

Keratin 14 (KRT14) Protein Profile

Protein Summary

This gene encodes a member of the keratin family, the most diverse group of intermediate filaments. This gene product, a type I keratin, is usually found as a heterotetramer with two keratin 5 molecules, a type II keratin. Together they form the cytoskeleton of epithelial cells. Mutations in the genes for these keratins are associated with epidermolysis bullosa simplex. At least one pseudogene has been identified at 17p12-p11.

Gene names and symbols associated with Keratin 14 Proteins (KRT14)

  • keratin 14 (KRT14)
  • keratin 14 (Krt14)
  • keratin 14, type I L homeolog (krt14.L)
  • AI626930 protein
  • CK14 protein
  • EBS3 protein
  • EBS4 protein
  • K14 protein
  • Ka14 protein
  • Krt-1.14 protein
  • Krt1-14 protein
  • NFJ protein
  • ouro2 protein

Protein level used designations for Keratin 14 Proteins (KRT14)

CK-14 , cytokeratin 14 , cytokeratin-14 , keratin 14 (epidermolysis bullosa simplex, Dowling-Meara, Koebner) , keratin, type I cytoskeletal 14 , keratin-14 , epidermolysis bullosa simplex, Dowling-Meara, Koebner , keratin complex 1, acidic, gene 14 , K14 , type I keratin Ka14 , cytokeratin VII , cytokeratin-7 , epidermal keratin VII , type I alpha-keratin 14 , keratin 14 , ouroboros 2 , keratin, type I cytoskeletal 14-like

GENE ID SPECIES
3861 Homo sapiens
16664 Mus musculus
287701 Rattus norvegicus
404111 Bos taurus
408039 Gallus gallus
100310818 Xenopus laevis
100400152 Callithrix jacchus
100713272 Cavia porcellus
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