Keratin 4 Proteins (KRT4)

The protein encoded by KRT4 is a member of the keratin gene family. Additionally we are shipping Keratin 4 Antibodies (134) and Keratin 4 Kits (5) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
KRT4 3851  
KRT4 315323 Q6IG00
KRT4 16682 P07744
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Top Keratin 4 Proteins at antibodies-online.com

Showing 6 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 60 Days
$9,626.73
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 60 Days
$9,626.73
Details
Escherichia coli (E. coli) Human His tag,T7 tag 100 μg 15 to 18 Days
$672.00
Details
Wheat germ Human GST tag 10 μg 11 to 12 Days
$414.29
Details
Yeast Rat His tag   1 mg 60 to 71 Days
$3,529.17
Details
Escherichia coli (E. coli) Rat His tag,S tag   100 μg 15 to 18 Days
$736.00
Details

KRT4 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Rat (Rattus) ,
,
Mouse (Murine)

More Proteins for Keratin 4 (KRT4) Interaction Partners

Human Keratin 4 (KRT4) interaction partners

  1. Study indicated the mutated KRT4 gene may play important roles in the pathogenesis of white sponge nevus.

  2. The aim of the study was to determine whether KRT4 or KRT13 gene mutation was the molecular basis of oral white sponge nevus. Deletion in the KRT4 gene was found to be a common polymorphism reflecting a high allele frequency of 31.25% in the Turkish population

  3. The crystal structure of recombinant Srr-1-K4BD(485-642) and its possible mode of interaction with K4 through docking studies, are reported.

  4. Identification of a mutation of the keratin 4 gene recurrent in a family affected by white sponge nevus.

  5. The aberrant expression of K4 and K13 and concomitant up-regulation of the other keratins may be one of the causative factors for morphological alterations in the affected epithelium.

  6. Fascin has a potential role as an early detection biomarker and CK4 as a tumor marker in esophageal squamous cell carcinoma.

  7. Deletion of the srr-1 gene in the genome of S. agalactiae revealed that this gene plays a role in bacterial binding to human K4 and that it is involved in adherence to epithelial HEp-2 cells.

  8. 2 new mutations were found in the keratin 4 gene, the heterozygous missense mutation 1829G-->A in exon 2B, and 2324A-->G in non-coding region, which may be related with the development of WSN.

  9. Failure to phosphorylate HsCyk-4 blocks Ect2 recruitment to the central spindle and the subsequent induction of furrowing.

  10. Data found that Plk1 binds and directly phosphorylates the HsCYK-4 at the midzone and this modification creates a major docking site for the tandem BRCT repeats of the Rho GTP exchange factor Ect2.

  11. Infection by HPV stimulates the expression of cytokeratin 4

Keratin 4 (KRT4) Protein Profile

Protein Summary

The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in differentiated layers of the mucosal and esophageal epithelia with family member KRT13. Mutations in these genes have been associated with White Sponge Nevus, characterized by oral, esophageal, and anal leukoplakia. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.

Gene names and symbols associated with Keratin 4 Proteins (KRT4)

  • keratin 4 (krt4)
  • keratin 4 (KRT4)
  • keratin 4 (Krt4)
  • AW108092 protein
  • cb59 protein
  • CK-4 protein
  • CK4 protein
  • CYK4 protein
  • etID20321.6 protein
  • K4 protein
  • Kb4 protein
  • Krt-2.4 protein
  • Krt2-4 protein
  • krt8 protein
  • wu:fa91a11 protein
  • wu:fd19e09 protein
  • wu:fl23c09 protein
  • zf-K8 protein

Protein level used designations for Keratin 4 Proteins (KRT4)

cytokeratin , keratin 8 , cytokeratin 4 , keratin, type II cytoskeletal 4 , type-II keratin Kb4 , CK-4 , K4 , cytokeratin-4 , keratin-4 , type II keratin Kb4 , 57kDa keratin , 57kd keratin , cytoskeletal 57 kDa keratin , keratin complex 2, basic, gene 4

GENE ID SPECIES
794486 Danio rerio
3851 Homo sapiens
315323 Rattus norvegicus
16682 Mus musculus
100682832 Canis lupus familiaris
101080551 Felis catus
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