Keratin 8 (KRT8) ELISA Kits

KRT8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Additionally we are shipping Keratin 8 Antibodies (983) and Keratin 8 Proteins (44) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
KRT8 3856 P05787
KRT8 16691 P11679
KRT8 25626 Q10758
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Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.039 ng/mL 0.156-10 ng/mL Typical standard curve 96 Tests Log in to see 15 to 18 Days
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More ELISA Kits for Keratin 8 Interaction Partners

Human Keratin 8 (KRT8) interaction partners

  1. Cytokeratin 5 (show KRT5 ELISA Kits)/6 and CK8/18 immunohistochemistry on 150 cases of triple negative breast cancers was performed and association with various clinicopathological features was evaluated.

  2. KRT8 mRNA and protein are upregulated in anaplastic thyroid carcinoma. KRT8 protein binds to annexin A2 (show ANXA2 ELISA Kits).

  3. K8/K18 (show KRT18 ELISA Kits) variants are overrepresented in Chinese NAFLD (show TSC2 ELISA Kits) patients and might accelerate liver fat storage through insulin (show INS ELISA Kits) resistance.

  4. regulated enhancement of autophagy with concurrent increased expression of KRT8 and the inhibition of KRT8 phosphorylation serve to inhibit oxidative stress-induced (show SQSTM1 ELISA Kits) epithelial-mesenchymal transitionof retinal pigment epithelium cells.

  5. Histopathological differences between Magnetic resonance-guided high-intensity focused ultrasound (MR-HIFU)-ablated tissue and radiofrequency (RF)-ablated tissue were demonstrated. CK-8 was more reliable for cell viability assessment than H&E when used directly after ablation

  6. Loss of activating transcription factor 3 (ATF3 (show ATF3 ELISA Kits)) in knockout mice promotes the emergence of keratins CK5 (show KRT5 ELISA Kits)+CK8+ epithelial cells.

  7. Data show that the filament elongation of both desmin (show DES ELISA Kits) and keratin K8/K18 (show KRT18 ELISA Kits) proceeds very similar to that of vimentin (show VIM ELISA Kits).

  8. New insights into interactions between the nucleotide-binding domain of CFTR (show CFTR ELISA Kits) and keratin 8.

  9. We present results of a multicentre study measuring UBC((R)) Rapid Test(test that detects fragments of cytokeratins 8 and 18 in urine) in bladder cancer patients and healthy controls with focus on carcinoma in situ (CIS) and high-grade bladder cancer.

  10. Data show that after siRNA transfection, TGF-beta1 (show TGFB1 ELISA Kits) protein level was decreased, and CK18 (show KRT18 ELISA Kits) proteins was decreased, while CK8 proteins was increased, and TERT (show TERT ELISA Kits) protein expression was slightly increased at 96 h.

Mouse (Murine) Keratin 8 (KRT8) interaction partners

  1. The authors found that keratin 8 suppressed toll (show TLR4 ELISA Kits)-like receptor-induced nuclear factor (NF)-kappaB (show NFKB1 ELISA Kits) activation and interacted with the adaptor tumor necrosis factor (TNF (show TNF ELISA Kits)) receptor-associated factor 6 (TRAF6 (show TRAF6 ELISA Kits)) to prevent its polyubiquitination.

  2. K8/K18 (show KRT18 ELISA Kits) interact with Notch1 (show NOTCH1 ELISA Kits) and regulate Notch1 (show NOTCH1 ELISA Kits) signalling activity during differentiation of the colonic epithelium.

  3. Mitochondria in K8 wild-type beta cells and MIN6 insulinoma cells overexpressing K8 and 18 are more stationary compared with mitochondria in keratin-deficient cells

  4. K8/K18 (show KRT18 ELISA Kits)-dependent PKCdelta (show PKCd ELISA Kits)- and ASMase (show SMPD1 ELISA Kits)-mediated modulation of lipid raft size can explain the more prominent FasR-mediated signaling resulting from K8/K18 (show KRT18 ELISA Kits) loss.

  5. DRA mRNA levels were decreased by three- to fourfold and DRA protein was almost entirely lost in K8-/- cecum and proximal and distal colon compared with K8+/+.

  6. Upregulation of IL-22 (show IL22 ELISA Kits) in combination with a complete loss of its negative regulator IL-22BP (show IL22RA2 ELISA Kits), and increased downstream STAT3 (show STAT3 ELISA Kits)-signaling in K8(-/-) and K8(-/-)Apc (show APC ELISA Kits)(Min/+) colonic epithelia confirmed that the IL-22 (show IL22 ELISA Kits) pathway, important in inflammation, proliferation and tissue regeneration

  7. Krt8 deletion (Krt8(-/-)) in a mouse model of cystic fibrosis (show S100A8 ELISA Kits) (F508del-Cftr (show CFTR ELISA Kits) mice) increased the levels of circulating markers of bone formation, corrected the expression of osteoblast phenotypic genes, promoted trabecular bone formation and improved bone mass and microarchitecture. Krt8 deletion corrected overactive NF-kappaB (show NFKB1 ELISA Kits) signaling & decreased Wnt (show WNT2 ELISA Kits)-beta-catenin (show CTNNB1 ELISA Kits) signaling induced by F508del-Cftr (show CFTR ELISA Kits) mutation in osteoblasts.

  8. Autoantibodies to several antigens were identified in 81% of K8-null male mice 8 mo or older. Similar autoantibodies were detected in aging K18 (show KRT18 ELISA Kits)-null male mice that had a related liver phenotype but normal colon compared with K8-null mice

  9. The regulation of the SCFA-MCT1 (show MCTS1 ELISA Kits)-HMGCS2 (show HMGCS2 ELISA Kits) axis is disrupted in K8(-/-) colonocytes, suggesting a role for keratins in colonocyte energy metabolism and homeostasis.

  10. In several liver stress models epiplakin and K8 genes displayed identical expression patterns and transgenic K8 overexpression resulted in elevated hepatic epiplakin levels.

Cow (Bovine) Keratin 8 (KRT8) interaction partners

  1. Results did not support that K8/K18 (show KRT18 ELISA Kits) filaments influence the expression of Fas (show FAS ELISA Kits) on the surface of luteal cells.

Zebrafish Keratin 8 (KRT8) interaction partners

  1. Data identify Danio rerio keratins 8/18 as the true orthologs of the human keratin pair 8/18.

Pig (Porcine) Keratin 8 (KRT8) interaction partners

  1. This study reveals clear genetic-statistical evidence for a link of KRT8, FAF1 (show FAF1 ELISA Kits) and PTH1R (show PTH1R ELISA Kits) with some of leg weakness related traits in pigs.

  2. Mechanical injury of vascular smooth muscle up-regulated keratin 8.

Keratin 8 (KRT8) Antigen Profile

Antigen Summary

This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene.

Gene names and symbols associated with Keratin 8 (KRT8) ELISA Kits

  • keratin 8 (KRT8) antibody
  • keratin 8 (Krt8) antibody
  • keratin 8 S homeolog (krt8.S) antibody
  • keratin 8 (krt8) antibody
  • AA960620 antibody
  • AL022697 antibody
  • AU019895 antibody
  • card2 antibody
  • cb186 antibody
  • CK-8 antibody
  • ck8 antibody
  • cyk8 antibody
  • CYKER antibody
  • DKFZp468F2127 antibody
  • DreK8 antibody
  • EndoA antibody
  • k2c8 antibody
  • K8 antibody
  • KERATIN8 antibody
  • KO antibody
  • Krt-2.8 antibody
  • krt2-5 antibody
  • krt2-8 antibody
  • KRT8 antibody
  • MGC69490 antibody
  • sb:cb186 antibody
  • wu:fa20h05 antibody
  • wu:fa95h10 antibody
  • wu:fb96c06 antibody
  • zf-K8 antibody
  • zfk8 antibody

Protein level used designations for Keratin 8 (KRT8) ELISA Kits

cytokeratin 8 , cytokeratin-8 , keratin, type II cytoskeletal 8 , type-II keratin Kb8 , CK-8 , cytokeratin endo A , keratin complex 2, basic, gene 8 , keratin-8 , K8 , KERA , cytokeratin-A , keratin 8 , keratin complex 2, basic, gene 5 , etID33550.23 , etID43142.23 , etID43142.8 , keratin, type 2, gene 8

3856 Homo sapiens
16691 Mus musculus
25626 Rattus norvegicus
281269 Bos taurus
380217 Xenopus laevis
426896 Gallus gallus
431676 Xenopus (Silurana) tropicalis
486513 Canis lupus familiaris
700449 Macaca mulatta
737628 Pan troglodytes
797433 Danio rerio
100152077 Sus scrofa
100174430 Pongo abelii
101110495 Ovis aries
100348891 Oryctolagus cuniculus
100736243 Cavia porcellus
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