anti-Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 2 (KIR2DL2) Antibodies

Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. Additionally we are shipping KIR2DL2 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
KIR2DL2 3803 P43627
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Top anti-KIR2DL2 Antibodies at

Showing 10 out of 45 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Human Rabbit Un-conjugated WB Western blot analysis of CD158b1 expression in MDAMB231 (A), Jurkat (B), mouse liver (C), H9C2 (D) whole cell lysates. 200 μL 13 to 14 Days
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of KIR2DL2 using NIH-3T3 whole cell lysates 100 μL 11 to 12 Days
Human Rabbit Un-conjugated ICC, IHC, WB DAB staining on IHC-P; Samples: Human Bile duct cancer Tissue 100 μg 13 to 16 Days
Human Rabbit Un-conjugated FACS, WB Western blot analysis in MDA-MB231,Jurkat cell line lysates (35ug/lane). Flow cytometric analysis of MDA-MB231 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL 2 to 3 Days
Human Mouse Un-conjugated FACS, IP   200 μg 11 to 14 Days
Human Rabbit Un-conjugated WB   100 μL 11 to 14 Days
Human Rabbit Biotin WB   100 μL 11 to 14 Days
Human Rabbit FITC WB   100 μL 11 to 14 Days
Human Rabbit Un-conjugated WB   100 μL 11 to 14 Days
Human Rabbit Un-conjugated FACS, WB   50 μg 11 to 14 Days

More Antibodies against KIR2DL2 Interaction Partners

Human Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 2 (KIR2DL2) interaction partners

  1. Our finding suggests that presentation of specific LASV epitopes by HLA-C alleles to the inhibitory KIR2DL2 receptor on NK cells could potentially prevent the killing of infected cells and provides insights into the mechanisms by which LASV can escape NK-cell-mediated immune pressure.

  2. The multivariate analysis revealed that the lack of KIR2DS2 (p = 0.035), the presence of KIR2DL3 (p = 0.075), and the presence of KIR2DL2HLA-C1 (p = 0.044) were risk factors for posttransplant cytomegalovirus infection.

  3. The results suggest that KIR2DL2 and 2DS4del could have a risk role in the development of Systemic Sclerosis, but not with clinical manifestations.

  4. Killer cell immunoglobulin like receptor two (KIR2DL2) shows a risk association with Chinese Han hepatitis C virus-1b (HCV-1b) patients not responding to the combination therapy of pegylated alpha interferon (PEG-IFN) with ribavirin (RBV).

  5. KIR2DL2/HLA-C( *)12:02 and KIR2DL2/HLA-C( *)14:03 compound genotypes have protective effects on control of HIV-1.

  6. KIR2DL2 gene polymorphism is associated with HIV-1 infection.

  7. association between KIR2DS2 and the response to methotrexate (MTX), moreover, the combination KIR2DL2+/KIR2DS2+ was more frequent in responders to MTX (p = 0.043).

  8. KIR2DL2/KIR2DL3-glutamate(35) alleles are functionally stronger than -glutamine(35) alleles.

  9. KIR2DL2/2DS2-C1C1 genotype is associated with type 1 diabetes in Saudi children

  10. genetic association study in population in Eastern India: Data suggest that interactions between KIRs (KIR2DL2, KIR2DS4, KIR2DL3) and HLA ligands (HLAC1, HLAC2) contribute significantly toward susceptibility and protection toward type 1 diabetes.

  11. Allelic polymorphism of KIR2DL2/2DL3 in a southern Chinese population.

  12. a significant increase in the frequency of KIR2DL2 (P = 0.019) as well as KIR2DS2 (P = 0.008) in patients with neuroblastoma compared with the healthy control group, was found.

  13. Single Nucleotide Polymorphism in KIR2DL2 gene is associated with Asthma and Atopic Dermatitis.

  14. genetic polymorphism is associated with chronic hepatitis C and levels of viremia in Poland

  15. KIR2DL2 and KIR2DS2 genotype is associated with protection against primary biliary cirrhosis in Han population.

  16. Genetic risk for co-occurrence of type 1 diabetes and celiac disease is modified by HLA-C and killer immunoglobulin-like receptors.

  17. Authors showed an increase in HLA-C1/KIR2DL2 and HLA-C1/KIR2DL3 pairs in human papillomavirus high-risk infected patients (OR 3.05, 3.24) with invasive cervical cancer (OR 1.33, 3.68).

  18. KIR2DL3-positive NK cells were more sensitive to changes in the peptide content of MHC class I than KIR2DL2-positive NK cells.

  19. Authors showed a significant increased correlation between KIR2DL2/DS2, type 2 diabetes and HLA-C1C1 genotype in the type 2 diabetes patients infected with human herpesvirus 8.

  20. these results suggest that inhibitory KIR2DL2 and KIR2DL3, which are alleles of the same locus, play a role in the inverse effects on PM and PM/HIV co-infection

KIR2DL2 Antigen Profile

Protein Summary

Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several 'framework' genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules\\\\; thus, KIR proteins are thought to play an important role in regulation of the immune response.

Gene names and symbols associated with KIR2DL2

  • killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 2 (KIR2DL2) antibody
  • CD158b antibody
  • CD158B1 antibody
  • NKAT6 antibody
  • p58.2 antibody

Protein level used designations for KIR2DL2

CD158 antigen-like family member B1 , MHC class I NK cell receptor , NKAT-6 , killer cell immunoglobulin-like receptor 2DL2 , natural killer-associated transcript 6 , p58 NK receptor CL-43 , p58 natural killer cell receptor clone CL-43

3803 Homo sapiens
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