Kinesin Family Member 20A (KIF20A) ELISA Kits

Mitotic kinesin required for chromosome passenger complex (CPC)-mediated cytokinesis. Additionally we are shipping Kinesin Family Member 20A Antibodies (89) and Kinesin Family Member 20A Proteins (5) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
KIF20A 10112 O95235
Anti-Mouse KIF20A KIF20A 19348 P97329
Anti-Rat KIF20A KIF20A 361308  
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Top Kinesin Family Member 20A ELISA Kits at antibodies-online.com

Showing 1 out of 7 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.049 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests Log in to see 13 to 16 Days
$736.84
Details

More ELISA Kits for Kinesin Family Member 20A Interaction Partners

Zebrafish Kinesin Family Member 20A (KIF20A) interaction partners

  1. Report expression of mt2 and smt-B upon cadmium exposure and cold shock in zebrafish (Danio rerio).

Human Kinesin Family Member 20A (KIF20A) interaction partners

  1. KIF20A-knockdown exhibits a suppressive effect on the cell cycle and has an inhibitory effect on the terminal cell division process (cytokinesis) leading to partial multinuclearity of the cells.

  2. In conclusion, our findings indicated that FOXM1 was highly expressed in lung cancer cells after exposure to ionizing radiation (IR). We also found that FOXM1 promoted radioresistance, invasion, migration, and EMT of lung cancer cells after IR, partly through upregulating KIF20A.

  3. Although the present study was preliminary, these data indicate the possible involvement of KIF20A in the proliferation of clearcell carcinoma (CCC), suggesting that targeting this molecule may contribute to reversing the malignant potential consequently affecting the oncologic outcome of CCC patients.

  4. Results suggest that coupling between actin and microtubule cytoskeletons driven by Myosin II and KIF20A ensures the spatial coordination between RAB6-positive vesicles fission from Golgi/trans-Golgi network membranes and their exit along microtubules.

  5. Study reveals the mechanism controlling abscission through integration of Aurora B kinase and B56-bound PP2A phosphatase activities on the kinesin motor protein MKlp2. MKlp2 is an essential protein for promoting abscission, which may regulate tethering and stabilizing of the PM to the microtubule cytoskeleton at the intercellular bridge through its previously uncharacterized lipid association motif.

  6. Identification of a novel autosomal recessive congenital restrictive cardiomyopathy, caused by a near complete loss-of-function of KIF20A.

  7. While the MKLP2 neck-linker is directed towards the microtubule plus-end in an ATP-like state, it does not fully dock along the motor domain. Furthermore, the footprint of the MKLP2 motor domain on the microtubule surface is altered compared to motile kinesins, and enhanced by kinesin-6-specific sequences.

  8. High KIF20A expression is associated with hepatocellular carcinoma.

  9. Study shows that the kinesin family member 20A (KIF20A) is a tumor-associated antigen involved in the glioma cell growth and cell survival, suggesting that KIF20A is an oncoantigen of gliomas.

  10. Signaling cascade of the NIMA-related kinases (Neks) Nek6, Nek7, and Nek9 is required for the localization and function of two kinesins essential for cytokinesis, Mklp2 and Kif14 to properly coordinate cytokinesis.

  11. KIF20A is overexpressed and may serve as an independent prognostic biomarker in Nasopharyngeal Cancer. Targeting KIF20A reduces migration and invasion of Nasopharyngeal Cancer cells.

  12. elevated KIF20A expression correlates with HPV infection, clinical stage, tumor recurrence, lymphovascular space involvement, pelvic lymph node metastasis, and poor outcome in early-stage cervical squamous cell carcinoma patients.

  13. we identify KIF20A as a direct transcriptional target of FOXM1, involved in paclitaxel action and resistance

  14. Our results provide insight into the link between regulation of KIF20A-mediated trafficking of IGF2BP3-containing stress granules and modulation of the motility and invasiveness in pancreatic cancers.

  15. Kif20a expression was upregulated in pancreatic ductal adenocarcinoma and pancreatic neuroendocrine cancer compared with normal pancreas. Kif20a silencing resulted in inhibition of proliferation, motility, and invasion of pancreatic cancer cell lines.

  16. Authors propose that phosphoregulation of MKlp2 by Cdk1/cyclin B1 ensures that activation of MKlp2 kinesin and relocation of the CPC occur at the appropriate time and space for proper mitotic progression and genomic stability.

  17. targeting Aurora B to the cell cortex (or the equatorial cortex) by MKlp2 is essential for the maintenance of the ingressing furrow for successful cytokinesis

  18. Primary melanomas that were positive for KIF20A showed a significantly greater thickness than those that were negative, and patients with KIF20A+ melanoma tended to develop recurrence earlier.

  19. Used proteomics to identify the genistein-induced protein alterations in gastric cancer cells and found the silencing of KIF20A inhibited cell viability and induced G2/M arrest,& also increased cancer cell sensitivity to genistein inhibition.

  20. This gene is not involved in Charcot-Marie-Tooth disease.

Mouse (Murine) Kinesin Family Member 20A (KIF20A) interaction partners

  1. It has been reported that mitotic kinesin KIF20A interacts with RGS3 and plays a crucial role in controlling the division modes of neural progenitor cells during cortical neurogenesis.

Kinesin Family Member 20A (KIF20A) Antigen Profile

Antigen Summary

Mitotic kinesin required for chromosome passenger complex (CPC)-mediated cytokinesis. Following phosphorylation by PLK1, involved in recruitment of PLK1 to the central spindle. Interacts with guanosine triphosphate (GTP)-bound forms of RAB6A and RAB6B. May act as a motor required for the retrograde RAB6 regulated transport of Golgi membranes and associated vesicles along microtubules. Has a microtubule plus end-directed motility.

Gene names and symbols associated with KIF20A

  • kinesin family member 20A (kif20a) antibody
  • kinesin family member 20A L homeolog (kif20a.L) antibody
  • kinesin family member 20A (KIF20A) antibody
  • kinesin-like protein KIF20A (LOC100223319) antibody
  • kinesin-like protein KIF20A (LOC100231271) antibody
  • kinesin family member 20A (Kif20a) antibody
  • AA415432 antibody
  • LOC325449 antibody
  • MGC79056 antibody
  • MGC112061 antibody
  • MKLP2 antibody
  • mt2 antibody
  • Rab6kifl antibody

Protein level used designations for KIF20A

kinesin family member 20A , metallothionein 2 , kinesin-like protein KIF20A-like , GG10_2 , RAB6 interacting, kinesin-like (rabkinesin6) , kinesin-like protein KIF20A , mitotic kinesin-like protein 2 , rab6-interacting kinesin-like protein , rabkinesin-6 , Rabkinesin-6 , kinesin-like protein 174

GENE ID SPECIES
325449 Danio rerio
446474 Xenopus laevis
462091 Pan troglodytes
496538 Xenopus (Silurana) tropicalis
100062393 Equus caballus
100223319 Taeniopygia guttata
100231271 Taeniopygia guttata
100345407 Oryctolagus cuniculus
100387561 Callithrix jacchus
100482186 Ailuropoda melanoleuca
100515193 Sus scrofa
100586722 Nomascus leucogenys
10112 Homo sapiens
416220 Gallus gallus
474693 Canis lupus familiaris
527854 Bos taurus
19348 Mus musculus
361308 Rattus norvegicus
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