Kruppel-Like Factor 11 (KLF11) ELISA Kits

The protein encoded by KLF11 is a zinc finger transcription factor that binds to SP1-like sequences in epsilon- and gamma-globin gene promoters. Additionally we are shipping KLF11 Antibodies (86) and KLF11 Proteins (4) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
KLF11 8462 O14901
KLF11 194655 Q8K1S5
Anti-Rat KLF11 KLF11 313994  
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Top KLF11 ELISA Kits at antibodies-online.com

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Catalog No. Reactivity Sensitivity Range Images Quantity Delivery Price Details
Human
  96 Tests 2 to 3 Days
$380.00
Details

More ELISA Kits for KLF11 Interaction Partners

Human Kruppel-Like Factor 11 (KLF11) interaction partners

  1. microRNA-30d mediated breast cancer invasion, migration, and epithelial-mesenchymal transition by targeting KLF11 and activating STAT3 pathway.

  2. KLF11 has a critical role in regulating gastric cancer migration and invasion by increasing Twist1 expression

  3. Profibrotic gene expression was activated in a primary human peritoneal cell line in response to KLF11 short hairpin RNA and medroxyprogesterone acetate but not estradiol.

  4. In endometrial-stromal fibroblasts, KLF11 recruited SIN3A/HDAC (histone deacetylase), resulting in COL1A1-promoter deacetylation and repression

  5. Results suggest a role for KLF11 in upregulating MAO-A in depressive disorder and chronic social stress, suggesting that inhibition of the pathways regulated by this transcription factor may aid in the therapeutics of neuropsychiatric illnesses

  6. The data suggest a relationship between promoter DNA methylation and KLF11 gene expression in ovarian cancer tumorigenesis.

  7. identified an evolutionarily conserved metabolic regulator, Kruppel-like factor 11 (KLF11), as a novel browning transcription factor in human adipocytes that is required for rosiglitazone-induced browning.

  8. KLF11 repressed most endometrial CYP enzymes

  9. Levels of KLF11 are significantly increased in the postmortem prefrontal cortex of subjects with alcohol dependence compared to controls.

  10. KLF11 regulates distinct gene networks.

  11. KLF111 represses glycodelin-A levels and influences its role in the ovarian endometrium.

  12. KLF11 is a critical transcription factor in the function of mesenchymal cells and, specifically, as a negative regulator of collagen secretion.

  13. Data identify a novel pathogenic role for KLF11 in preventing de novo disease-associated fibrosis in endometriosis.

  14. The A347S mutation disrupted KLF11-mediated increases in basal insulin levels and promoter activity and blunted glucose-stimulated insulin secretion.

  15. Data indicate that median methylation levels of BCAN, HOXD1, KCTD8, KLF11, NXPH1, POU4F1, SIM1, and TCF7L1 were >/=30% higher than in normal samples, representing potential biomarkers for tumor diagnosis.

  16. KLF11 has a role in fine-tuning insulin transcription in certain cellular situations rather than representing a major transcriptional activator or repressor of the insulin gene.

  17. Kruppel-like factor-11, a transcription factor involved in diabetes mellitus, suppresses endothelial cell activation via the nuclear factor-kappaB signaling pathway.

  18. KLF11 is an MAO A regulator and is produced in response to neuronal stress, which transcriptionally activates MAO A.

  19. Here we report the characterization of two antagonistic, chromatin-mediated mechanisms by which KLF11 regulated the transcription of the dopamine D2 receptor.

  20. A PXVXL HP1-interacting domain identified at position 487-491 of KLF11 mediates the binding of HP1alpha and KLF11 in vitro and in cultured cells.

Mouse (Murine) Kruppel-Like Factor 11 (KLF11) interaction partners

  1. KLF11 acts as a novel protective factor in ischemic stroke.

  2. Consistent with loss of Klf11-mediated activation, lesions in Klf11-/- animals were associated with progressive fibrosis and decreased Drd2 expression.

  3. Using a sterile peritonitis model, fibrosis selectively developed in Klf11-/- females. Fibrosis in these animals was almost completely abrogated by ovariectomy. Ovariectomized animals were selectively supplemented with estradiol, medroxyprogesterone acetate (MPA), or dihydrotestosterone; fibrosis was only observed in mice exposed to MPA.

  4. TGFbeta and KLF11 mediate critical, translationally relevant host and lesion-driven responses that enable establishment and progression of endometriosis.

  5. Results suggest a role for KLF11 in upregulating MAO-A in depressive disorder and chronic social stress, suggesting that inhibition of the pathways regulated by this transcription factor may aid in the therapeutics of neuropsychiatric illnesses

  6. Data show that the major phenotype given by the whole-body deletion of Kruppel-like factor 11 (Klf11) is not diabetes but increased insulin sensitivity.

  7. Loss of KLF11 expression is associated with hyperglycemia in Type 2 diabetes.

  8. this study revealed a new role for the KLF11 gene in the mechanisms underlying the antinociceptive effects of chronic ethanol exposure

  9. KLF11 is a critical transcription factor in the function of mesenchymal cells and, specifically, as a negative regulator of collagen secretion.

  10. Taken together, our findings identify a novel anti-hypertrophic and anti-fibrotic role of KLF11, and KLF11 activator may serve as candidate drug for heart failure patients.

  11. Overexpression of KLF11 in the livers of diabetic and obese mice activates the PPARalpha signaling pathway, subsequently markedly improving the fatty liver phenotype. Knockdown of KLF11 increases hepatic triglycerides.

  12. Data identify a novel pathogenic role for KLF11 in preventing de novo disease-associated fibrosis in endometriosis.

  13. Recruitment of KLF11 as a novel co-regulator (with peroxisome proliferator-activated receptor PPARgamma) plays a critical role in cerebrovascular protection after ischemic insults.

  14. Kruppel-like factor-11, a transcription factor involved in diabetes mellitus, suppresses endothelial cell activation via the nuclear factor-kappaB signaling pathway.

  15. KLF11 is an MAO A regulator and is produced in response to neuronal stress, which transcriptionally activates MAO A.

  16. an important role for KLF11 in the regulation of INS transcription via the novel c.-331 KLF site.

  17. the expression of TIEG1 and TIEG2 was specific in different organs yet varied with different developmental time points.

  18. KLF11 is downregulated in human cancers, inhibits cell growth in vitro and in vivo, and suppresses neoplastic transformation

  19. results from genetic knockout suggest that KLF11 is not absolutely required for hematopoiesis, growth, and development

  20. Tieg3/Klf11 is a downstream mediator of TGF-beta-induced apoptosis in the oligodendroglial cell line OLI-neu by transcriptional repression of Smad7

KLF11 Antigen Profile

Antigen Summary

The protein encoded by this gene is a zinc finger transcription factor that binds to SP1-like sequences in epsilon- and gamma-globin gene promoters. This binding inhibits cell growth and causes apoptosis. Defects in this gene are a cause of maturity-onset diabetes of the young type 7 (MODY7). Three transcript variants encoding two different isoforms have been found for this gene.

Gene names and symbols associated with KLF11

  • Kruppel like factor 11 (KLF11) antibody
  • Kruppel-like factor 11 (Klf11) antibody
  • Kruppel-like factor 11 L homeolog (klf11.L) antibody
  • Kruppel-like factor 11a (klf11a) antibody
  • Kruppel-like factor 11 (klf11) antibody
  • Krueppel-like factor 11 (LOC100194692) antibody
  • Kruppel like factor 11 (Klf11) antibody
  • Kruppel-like factor 11b (klf11b) antibody
  • 9830142A17 antibody
  • D12Ertd427e antibody
  • fklf antibody
  • fklf1 antibody
  • klf11 antibody
  • MGC145216 antibody
  • mody7 antibody
  • si:dkey-81b15.5 antibody
  • Tcfcp2l2 antibody
  • TIEG-2 antibody
  • tieg2 antibody
  • Tieg2b antibody
  • tieg3 antibody
  • wu:fc45c07 antibody
  • wu:fj44b12 antibody
  • zgc:153255 antibody
  • zgc:154048 antibody

Protein level used designations for KLF11

Krueppel-like factor 11 , TGFB-inducible early growth response protein 2 , TIEG-2 , transforming growth factor-beta-inducible early growth response protein 2 , TGFB inducible early growth response 2 , TGFB inducible early growth response 3 , TGFB-inducible early growth response protein 2b , TGFB-inducible early growth response protein 3 , TIEG-3 , transforming growth factor-beta-inducible early growth response protein 3 , transcription factor CP2-like 2 , Kruppel-like factor 11 , TIEG2 , TGF-beta inducible early growth response protein 2 , novel kruppel-like factor family protein , krueppel-like factor 11-like , Krueppel-like factor 11-like , Kruppel-like factor 11b

GENE ID SPECIES
8462 Homo sapiens
194655 Mus musculus
313994 Rattus norvegicus
421934 Gallus gallus
444439 Xenopus laevis
459023 Pan troglodytes
475665 Canis lupus familiaris
560787 Danio rerio
616730 Bos taurus
702323 Macaca mulatta
733909 Xenopus (Silurana) tropicalis
100031998 Monodelphis domestica
100174954 Sus scrofa
100194692 Salmo salar
100436340 Pongo abelii
100465756 Ailuropoda melanoleuca
100607386 Nomascus leucogenys
100715755 Cavia porcellus
100072433 Equus caballus
559076 Danio rerio
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