anti-Kruppel-Like Factor 5 (Intestinal) (KLF5) Antibodies

KLF5 encodes a member of the Kruppel-like factor subfamily of zinc finger proteins. Additionally we are shipping KLF5 Kits (9) and KLF5 Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
KLF5 84410  
KLF5 12224 Q9Z0Z7
KLF5 688 Q13887
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Top anti-KLF5 Antibodies at antibodies-online.com

Showing 10 out of 77 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of KLF5 antibody (Center) in CEM cell line lysates (35ug/lane). KLF5 (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$484.00
Details
Human Rabbit Un-conjugated FACS, IF, IHC (p), WB Western blot analysis of KLF5 antibody (C-term) (ABIN391515) in mouse stomach tissue lysates (35 µg/lane). KLF5 (arrow) was detected using the purified polyclonal antibody. KLF5 Antibody (C-term) (ABIN391515) IHC analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10 to 11 Days
$385.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of KLF5 antibody (Center) (ABIN391516) in CEM cell line lysates (35 µg/lane). KLF5 (arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10 to 11 Days
$385.00
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Immunohistochemistry-Paraffin: KLF5 Antibody [NBP1-88508] - Staining of human testis shows strong nuclear positivity in seminiferus tubules. Western Blot: KLF5 Antibody [NBP1-88508] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.Lane 2: Human cell line RT-4.Lane 3: Human cell line U-251MG sp 0.1 mL Log in to see 10 to 13 Days
$494.38
Details
Human Rabbit Un-conjugated ELISA, IHC, WB ABIN6269502 at 1/100 staining human kidney tissue sections by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. Western blot analysis of Phospho-KLF5(Ser303) in lysates of A549, using Phospho-KLF5(Ser303) Antibody(ABIN6269502). 100 μL Log in to see 11 to 12 Days
$450.00
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of Hela whole cell lysates, using KLF5  Antibody. The lane on the left is treated with the antigen-specific peptide. 100 μL Log in to see 11 to 12 Days
$390.77
Details
Human Rabbit Un-conjugated WB Anti-KLF5 antibody, Western blotting Lane 1: HELA Cell Lysate Lane 2: MCF-7 Cell Lysate 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated ICC, IF, IHC (p), WB WB Image Sample (30 ug of whole cell lysate) A: H1299 10% SDS PAGE BTEB2 antibody antibody diluted at 1:1000 IHC-P Image KLF5 antibody detects KLF5 protein at nucleus on HeLa xenograft by immunohistochemical analysis. Sample: Paraffin-embedded HeLa xenograft. KLF5 antibody , dilution: 1:500. 100 μL Log in to see 3 to 4 Days
$466.18
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), IP, WB Immunocytochemistry/Immunofluorescence: KLF5 Antibody [NBP1-32245] - Paraformaldehyde-fixed mouse ESC D3, using antibody at 1:200 dilution. Western Blot: KLF5 Antibody [NBP1-32245] - Sample (30 ug of whole cell lysate) A: H1299 10% SDS PAGE BTEB2 antibody, antibody diluted at 1:1000. 100 μL Log in to see 8 to 11 Days
$516.98
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded mouse embryo labeled with Rabbit Anti KLF5/UKHC Polyclonal Antibody, Unconjugated (ABIN739515) at 1:200 followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin-embedded rat brain labeled with Anti-KLF5/UKHC Polyclonal Antibody, Unconjugated (ABIN739515) 1:200, overnight at 4°C, The secondary antibody was Goat Anti-Rabbit IgG, Cy3 conjugated used at 1:200 dilution for 40 minutes at 37°C. 100 μL Log in to see 3 to 7 Days
$329.45
Details

Top referenced anti-KLF5 Antibodies

  1. Human Polyclonal KLF5 Primary Antibody for IF (p), IHC (p) - ABIN739515 : Zhang, Ha, Larouche, Swanson, Goldowitz: Kruppel-Like Factor 4 Regulates Granule Cell Pax6 Expression and Cell Proliferation in Early Cerebellar Development. in PLoS ONE 2015 (PubMed)

  2. Human Polyclonal KLF5 Primary Antibody for ICC, IF - ABIN4329154 : Chen, Lin, Tang: Matrix-Stiffness-Regulated Inverse Expression of Krüppel-Like Factor 5 and Krüppel-Like Factor 4 in the Pathogenesis of Renal Fibrosis. in The American journal of pathology 2015 (PubMed)

  3. Human Polyclonal KLF5 Primary Antibody for FACS, IF - ABIN391515 : Guo, Dong, Zhang, Zhao, Sun, Li, Dong: Pro-proliferative factor KLF5 becomes anti-proliferative in epithelial homeostasis upon signaling-mediated modification. in The Journal of biological chemistry 2009 (PubMed)
    Show all 2 Pubmed References

More Antibodies against KLF5 Interaction Partners

Mouse (Murine) Kruppel-Like Factor 5 (Intestinal) (KLF5) interaction partners

  1. these results show for the first time that Klf5 has a unique role suppressing ERK activity in Mouse embryonic stem cells.

  2. KLF5 expression is elevated in the aortic tissue of atherosclerosis mice, as compared to control mice.

  3. High KLF5 expression may play a pivotal role in the pathogenesis of congenital cystic adenomatoid malformation of the lungs partly through regulating the activity of MMP-9.

  4. These results indicate that Klf5 plays a critical role in the ductular reaction and biliary epithelial tissue expansion and remodeling by inducing biliary epithelial cell proliferation and thereby contributing to liver regeneration.

  5. any one of Klf2, Klf4 and Klf5 was sufficient to support self-renewal of mouse embryonic stem cells, whereas the removal of all three compromised it.

  6. the regulatory crosstalk between KLF5, miR-29a, and Fbw7/CDC4 cooperatively promotes atherosclerotic development

  7. KLF5 as an essential factor required for acinar-to-ductal metaplasia and oncogenic KRAS-induced pancreatic tumor formation.

  8. lf5 ChIP-seq revealed that Klf5 binding overlaps that of MyoD and Mef2, and Klf5 physically associates with both MyoD and Mef2. In addition, MyoD recruitment was greatly reduced in the absence of Klf5. These results indicate that Klf5 is an essential regulator of skeletal muscle differentiation, acting in concert with myogenic transcription factors such as MyoD and Mef2.

  9. KLF5 regulates intestinal barrier function by mediating the transcription of DSG2, a gene encoding a major component of desmosome structures

  10. Klf5 suppresses Fgf4-Fgfr-ERK signalling, thus preventing precocious activation of the primitive endoderm specification programme

  11. In conclusion, the results of this study suggest that the presence of KLF5 in postn-positive cells contributes to the pathogenesis of aortic thickening induced by DOCA-salt hypertension.

  12. these studies demonstrate dual functions of Klf5 in regulating hematopoietic stem and progenitor proliferation and localization in the bone marrow, as well as lineage choice after GMP, promoting increased neutrophil output at the expense of eosinophil production.

  13. Collectively, we identify a novel regulatory pathway in which 1, 25(OH)2D3 induces VDR expression and promotes VDR interaction with p50 subunit of NF-kappaB, which in turn attenuates the association of KLF5 with p50 subunit of NF-kappaB and thus exerts anti-inflammatory and anti-proliferative effects on macrophages.

  14. KLF5-dependent regulation of Myo9b/RhoA is required for podosome formation and macrophage migration during abdominal aortic aneurysm.

  15. Data show that R-Smad Proteins SMAD1 and SMAD5, which transduce bone morphogenetic protein (BMP) signals, recognize enhancer regions together with Kruppel-like factors KLF4 and KLF5 in naive embryonic stem cell (mESCs).

  16. illustrates that KLF5 may modulate DNA repair pathways to prevent intestinal injury induced by TBI. KLF5 signaling provides a novel field for identification of potential therapeutic targets for the treatment of radiation-induced intestinal damage

  17. Cardiac myocyte KLF5 is a transcriptional regulator of Ppara and cardiac energetics.

  18. In embryonic stem cells, we show that Klf5, but not JunB is a key LIF effector of cell plasticity.

  19. the regulatory functions of Klf5 acetylation in ESC self-renewal and differentiation

  20. unravels a novel mechanism how matrix stiffness regulates cellular proliferation and highlights the importance of matrix stiffness-modulated Klf5/Klf4 in the regulation of renal physiologic functions and fibrosis progression

Human Kruppel-Like Factor 5 (Intestinal) (KLF5) interaction partners

  1. the positive feedback loop of KLF5/CASC15/miR-153-3p/KLF5 in the acceleration of breast cancer malignant behaviors and tumorigenesis, is reported.

  2. these data suggested that the elevated cav-1 promoted pituitary adenoma cells migration and invasion by regulating the interaction between EGR1 and KLF5.

  3. Silencing CINP had the most potent inhibitory effect on cell growth in KLF5-expressing cells but did not affect parental TSU-Pr1 cells. Further analyses not only confirmed the physical interaction between KLF5 and CINP, also demonstrated that knockdown of CINP attenuated the effects of KLF5 on cell cycle progression, apoptosis and tumorigenesis.

  4. The miR-152/KLF5 axis may provide novel therapeutic targets for CC treatment.

  5. PVT1, KLF5, and beta-catenin were also revealed to be co-expressed in clinical TNBC samples.

  6. Was greatly suppressed by the silence of KLF5, GCN5, or GDF15.

  7. KLF5 may play an important role in odontoblast differentiation and dentin formation.

  8. Utilizing data from CRISPR/Cas9 gene knockout screening, authors reveal that cancer cells with KLF5 overexpression are dependent on KLF5 for their proliferation, suggesting KLF5 as a putative therapeutic target.

  9. KLF5 and TNFRSF11a are related to cervical cancer. KLF5 promotes the proliferation, migration, and invasion of cervical cancer cells partly by upregulating the transcription of TNFRSF11a.

  10. These results revealed that KLF5 promotes the tumorigenesis and metastasis of thyroid cancer cells and may be a potential therapeutic target in patients with thyroid cancer

  11. the present findings were the first to show that KLF5 expression and nitration by iNOS-mediated peroxynitrite are necessary for the induction of TNF-alpha and IL-1beta expression in VSMCs of diabetic vascular tissues.

  12. the results of the present study suggested that the miR5905p/KLF5 axis may regulate osteosarcoma (OS)progression and thus, may be a novel therapeutic target for the treatment of patients with OS.

  13. Study showed that KLF5 expression was increased in intracranial aneurysms (IAs) patients compared to that of normal subjects, and KLF5 overexpression vascular smooth muscle cells proliferation, migration, and phenotypic modulation, suggesting that the upregulated KLF5 expression played an important role in the induction of IAs.

  14. correlation between the KLF5 and ZEB1 transcription levels in the pancreatic tumor tissues

  15. The present study has identified that KLF5, a target of miR-145-5p, is a key marker gene in cancer. miR-145-5p may also contribute to the dysregulation of other functional genes during tumor development.

  16. the knockdown of HDAC1/2 upregulated KLF5 protein but not KLF5 mRNA, and the increase in KLF5 protein level by silencing HDAC1/2 was at least in part due to decreased proteasomal degradation.

  17. KLF5 expression in tumor stroma was closely associated with clinicopathological features such as tumor size, invasion depth, cell grade and lymph node metastasis, as well as poor prognosis in patients with gastric cancer.

  18. KLF5 has a role in regulating IL1beta induced intervertebral disc metabolism

  19. Levels of KLF5 are increased in human pancreatic ductal adenocarcinoma.

  20. Data demonstrate that KLF5 inhibits ccRCC growth as a tumor suppressor and highlight the potential of 5-Aza-CdR to release KLF5 expression as a therapeutic modality for the treatment of ccRCC.

KLF5 Antigen Profile

Protein Summary

This gene encodes a member of the Kruppel-like factor subfamily of zinc finger proteins. Since the protein localizes to the nucleus and binds the epidermal growth factor response element, it is thought to be a transcription factor.

Gene names and symbols associated with KLF5

  • Kruppel like factor 5 (KLF5) antibody
  • Kruppel-like factor 5 (intestinal) S homeolog (klf5.S) antibody
  • Kruppel-like factor 5 (Klf5) antibody
  • 4930520J07Rik antibody
  • bteb2 antibody
  • CKLF antibody
  • IKLF antibody
  • klf5 antibody
  • MGC115081 antibody

Protein level used designations for KLF5

Kruppel-like factor 5 (intestinal) , Krueppel-like factor 5-like , Kruppel-like factor 5 , basic-transcription-element-binding-protein 2 , basic transcription element binding protein 2 , basic transcription element binding protein BTEB2 , BTE-binding protein 2 , Krueppel-like factor 5 , basic transcription element-binding protein 2 , intestinal-enriched krueppel-like factor , transcription factor BTEB2 , GC box binding protein 2 , GC-box-binding protein 2 , colon krueppel-like factor , colon kruppel-like factor , intestinal-enriched kruppel-like factor

GENE ID SPECIES
100052058 Equus caballus
452597 Pan troglodytes
100010455 Monodelphis domestica
100231095 Taeniopygia guttata
100467044 Ailuropoda melanoleuca
100607414 Nomascus leucogenys
735138 Xenopus laevis
100008718 Oryctolagus cuniculus
84410 Rattus norvegicus
12224 Mus musculus
688 Homo sapiens
418818 Gallus gallus
612788 Canis lupus familiaris
100038005 Sus scrofa
535702 Bos taurus
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