LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1) ELISA Kits

The protein encoded by LIMS1 is an adaptor protein which contains five LIM domains, or double zinc fingers. Additionally we are shipping LIM and Senescent Cell Antigen-Like Domains 1 Antibodies (69) and LIM and Senescent Cell Antigen-Like Domains 1 Proteins (5) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
LIMS1 3987 P48059
Anti-Rat LIMS1 LIMS1 499443  
Anti-Mouse LIMS1 LIMS1 110829 Q99JW4
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Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.056 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests Log in to see 13 to 16 Days

More ELISA Kits for LIM and Senescent Cell Antigen-Like Domains 1 Interaction Partners

Human LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1) interaction partners

  1. High LIMS1 expression is associated with Neuroblastoma.

  2. focal adhesion signaling to actin cytoskeleton is implicated in human laryngeal carcinogenesis and PINCH1 has prognostic significance in the disease.

  3. that PINCH-1 may be playing an important role in etiopathogenesis of both subtypes breast cancer

  4. Mammalian cells have two functional PINCH proteins, PINCH1 and PINCH2. PINCH not only binds to Nck2 and engages in the signaling of growth factor receptors, but also forms a ternary complex with ILK (show ILK ELISA Kits) and parvin (IPP (show IPP ELISA Kits) complex).

  5. our data suggest an essential role of PINCH1, ILK (show ILK ELISA Kits) and ILKAP (show ILKAP ELISA Kits) for the radioresistance of p53 (show TP53 ELISA Kits)-wildtype glioblastoma multiforme cells

  6. Data suggest that PINCH1 and Nck2 critically participate in the regulation of cellular radiosensitivity and EGFR (show EGFR ELISA Kits) function and downstream signaling in a cellular model of human squamous cell carcinoma.

  7. Downregulation of PINCH1 is associated with metastatic breast cancer.

  8. changes in CSF (show CSF2 ELISA Kits) levels of PINCH appear to correlate with changes in blood CD4 (show CD4 ELISA Kits) count and with changes in CSF (show CSF2 ELISA Kits) hyperphosphorylated Tau levels

  9. two novel genes, galectin 9 (show LGALS9 ELISA Kits) and PINCH, were expressed at much higher levels in cancerous lesions than in normal tissues in all the patients with clear-cell carcinoma who were examined

  10. PINCH predicts survival in rectal cancer patients with RT, but not in patients without RT. The expression of PINCH may be regulated by radiation and by environmental factors surrounding the cells.

Mouse (Murine) LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1) interaction partners

  1. findings suggest that PINCH-1 regulates integrin-mediated adhesion of keratinocytes through the interactions with ILK as well as EPLIN.

  2. Rsu-1 (show RSU1 ELISA Kits) expression is dramatically decreased in PINCH double knockout mouse livers.

  3. PINCH is increased and binds to hp-Tau. These studies address a new mechanism by which AD and HIV may intersect and identify PINCH as a contributing factor to the accumulation of hyperphosphorylated Tau.

  4. PINCH-1 inhibits JNK (show MAPK8 ELISA Kits)-mediated apoptosis by stabilising the PINCH-1 binding protein RSU-1 (show RSU1 ELISA Kits) and promotes Bcl-2 (show BCL2 ELISA Kits)-dependent pro-survival signalling downstream of integrins.

  5. Data suggest that the adapter protein (show GRB10 ELISA Kits) PINCH1 critically participates in the regulation of the cellular radiosensitivity of normal and malignant cells similarly under adhesion and suspension conditions.

  6. PINCH1 plays an essential role in early murine embryonic development but is dispensable in ventricular cardiomyocytes.

  7. These results provide important evidence for a crucial role of the PINCH-1-ILK-alpha-parvin complex in the control of podocyte adhesion, morphology, and survival.

  8. LIM (show PDLIM5 ELISA Kits) 5 domain of PINCH1 interacts with Rsu-1 (show RSU1 ELISA Kits) in mammalian cells and functions, in part, by altering cell adhesion.

  9. The PINCH1 is composed of 5 LIM domains, binds ILK and locates to integrin-mediated adhesion sites, and PINCH1 is for integrin function, actin organization, cell-cell adhesion and endodermal cell survival during the implanting of mouse embryos.

  10. PICH1, Ilk and alpha-parvin form a complex to costameres in neonatal mouse ventricular myocytes. This complex is stimulated by fibronectins and phenylephrine, and by both by drug synergism, to regulate cardiac myocyte hypertrophy.

LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1) Antigen Profile

Antigen Summary

The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with LIMS1

  • LIM zinc finger domain containing 1 (LIMS1) antibody
  • LIM zinc finger domain containing 1 (Lims1) antibody
  • LIM and senescent cell antigen-like domains 1 (Lims1) antibody
  • 2310016J22Rik antibody
  • 4921524A02Rik antibody
  • AI507642 antibody
  • AU021743 antibody
  • AW551584 antibody
  • C430041B13Rik antibody
  • Lims1l antibody
  • LIMS3 antibody
  • LIMS3L antibody
  • PINCH antibody
  • PINCH-1 antibody
  • Pinch1 antibody
  • RGD1560732 antibody

Protein level used designations for LIMS1

LIM and senescent cell antigen-like-containing domain protein 1 , particularly interesting new Cys-His protein 1 , renal carcinoma antigen NY-REN-48

3987 Homo sapiens
499443 Rattus norvegicus
414880 Gallus gallus
474540 Canis lupus familiaris
100511559 Sus scrofa
540281 Bos taurus
110829 Mus musculus
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