anti-Laeverin (AQPEP) Antibodies

Metalloprotease which may be important for placentation by regulating biological activity of key peptides at the embryo- maternal interface. Additionally we are shipping AQPEP Kits (8) and AQPEP Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
Anti-Rat AQPEP AQPEP 502160  
AQPEP 206338 Q6Q4G3
Anti-Mouse AQPEP AQPEP 74574  
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Top anti-AQPEP Antibodies at

Showing 4 out of 4 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC, IHC (p) Immunohistochemistry: Laeverin Antibody [NBP2-47404] - Analysis of human placenta tissue. Shows strong membranous positivity in a subset of trophoblastic cells. Immunohistochemistry-Paraffin: Laeverin Antibody  - Staining of human placenta shows moderate membranous positivity in extra villous trophoblastic cells. 0.1 mL Log in to see 10 to 13 Days
Human Mouse Un-conjugated WB Western Blot analysis of LVRN expression in transfected 293T cell line by LVRN MaxPab polyclonal antibody.Lane 1: FLJ90650 transfected lysate(21.78 KDa).Lane 2: Non-transfected lysate. 50 μg Log in to see 11 to 12 Days
Human Rabbit Un-conjugated ELISA, WB   80 μL Log in to see 11 to 14 Days
Human Rabbit Un-conjugated IHC, ELISA, WB   100 μg Log in to see 11 to 16 Days

More Antibodies against AQPEP Interaction Partners

Human Laeverin (AQPEP) interaction partners

  1. Laeverin is expressed in all trophoblast cell types of normal and preeclamptic placentas. Expression pattern of laeverin in trophoblast cells is heterogeneous and not necessarily membrane-bound.

  2. In preeclamptic placentas, laeverin is experssed in the cytoplasm and microvesicles, rather than the cell membrane. Laeverin appears to be involved in trophoblast cell migration and invasion through interaction with integrins and matrix metalloprotease 1.

  3. Laeverin is a specific cell-surface marker for human extravillous trophoblast (EVT) and plays a regulatory role in EVT migration.

  4. Replacement of glutamine-238 with alanine caused a significant change in substrate specificity rather than a decrease in enzymatic activity.

  5. These results indicate that His(379) of laeverin plays essential roles in its distinctive enzymatic properties and contributes to maintaining the appropriate structure of the catalytic cavity of the enzyme.

  6. Extravillous trophoblasts express laeverin, a novel protein that belongs to membrane-bound gluzincin metallopeptidases(laeverin)

  7. The 3 most significantly overexpressed genes in rheumatoid arthritis were laeverin, 11beta-hydroxysteroid dehydrogenase type 2 (a steroid pathway enzyme), and cysteine-rich, angiogenic inducer 61 (a known angiogenic factor).

  8. is a novel bestatin-sensitive leucine aminopeptidase; plays important roles in human placentation by regulating biological activity of key peptides at the embryo-maternal interface

  9. A novel membrane-bound cell surface peptidase, laeverin (FLJ90650), was found to be specifically expressed on extravillous trophoblasts that had almost ceased invasion into maternal decidual tissues.

AQPEP Antigen Profile

Protein Summary

Metalloprotease which may be important for placentation by regulating biological activity of key peptides at the embryo- maternal interface. On synthetic substrates it shows a marked preference for Leu-4-methylcoumaryl-7-amide (Leu-MCA) over Met- MCA, Arg-LCA and Lys-LCA. Cleaves the N-terminal amino acid of several peptides such as angiotensin-3, kisspeptin-10 and endokinin C.

Gene names and symbols associated with anti-Laeverin (AQPEP) Antibodies

  • laeverin (Lvrn) antibody
  • laeverin (LVRN) antibody
  • APQ antibody
  • Aqpep antibody
  • LVRN antibody
  • RGD1562779 antibody

Protein level used designations for anti-Laeverin (AQPEP) Antibodies

aminopeptidase Q , laeverin , AP-Q , CHL2 antigen

502160 Rattus norvegicus
525695 Bos taurus
696886 Macaca mulatta
100353757 Oryctolagus cuniculus
206338 Homo sapiens
74574 Mus musculus
Selected quality suppliers for anti-AQPEP (AQPEP) Antibodies
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