anti-Laminin, alpha 1 (LAMA1) Antibodies

Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.. Additionally we are shipping Laminin alpha 1 Kits (21) and Laminin alpha 1 Proteins (9) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
LAMA1 16772 P19137
LAMA1 284217 P25391
LAMA1 316758  
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Top anti-Laminin alpha 1 Antibodies at antibodies-online.com

Showing 10 out of 68 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated IHC, IHC (p), WB Immunohistochemistry: LAMA1 Antibody (CL3087) [NBP2-42389] - Staining of human testis shows moderate immunoreactivity in basement membrane of seminiferous tubules. Immunohistochemistry: LAMA1 Antibody (CL3087) [NBP2-42389] - Staining of human lymph node shows absence of immunoreactivity in lymphoid tissue (negative control). 0.1 mL Log in to see 10 to 13 Days
$491.63
Details
Human Rabbit Un-conjugated IF, ELISA Immunofluorescence analysis of COS7 cells, using LAMA1 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Mouse Rabbit Un-conjugated ICC, IHC, WB Figure. DAB staining on IHC-P; Samples: Mouse Brain Tissue. 100 μg Log in to see 15 to 18 Days
$324.00
Details
Human Rabbit Un-conjugated IHC, IHC (p) Immunohistochemistry-Paraffin: LAMA1 Antibody [NBP2-34181] - Immunohistochemical staining of human stomach, lower shows strong cytoplasmic positivity in glandular cells with distinctly stained extracellular material. Immunohistochemistry-Paraffin: LAMA1 Antibody [NBP2-34181] - stomach 2 0.1 mL Log in to see 10 to 13 Days
$491.63
Details
Human Rabbit Un-conjugated ICC, IHC, WB Used in DAB staining on fromalin fixed paraffin- embedded liver tissue 100 μg Log in to see 13 to 16 Days
$316.00
Details
Human Rabbit Un-conjugated ICC, IHC, WB Used in DAB staining on fromalin fixed paraffin-embedded Kidney tissue 100 μg Log in to see 15 to 18 Days
$316.00
Details
Rat Rabbit Un-conjugated ICC, IHC, WB Used in DAB staining on fromalin fixed paraffin- embedded testis tissue 100 μg Log in to see 13 to 16 Days
$342.00
Details
Human Goat Un-conjugated FACS, IHC, WB Detection of Laminin alpha 1 in U2OS Human Cell Line by Flow Cytometry. U2OS human osteosarcoma cell line was stained with Goat Anti-Human Laminin alpha 1 Antigen Affinity-Purified Polyclonal Antibody. 100 μg Log in to see 8 to 9 Days
$416.30
Details
Human Rabbit Un-conjugated ELISA, IF   100 μL Log in to see 16 Days
$181.73
Details
Mouse Rabbit Un-conjugated IF/ICC, IHC, IP, WB Western blot analysis of recombinant Mouse LAMa1. IHC-P analysis of Mouse Intestine Tissue, with DAB staining. 100 μg Log in to see 11 to 18 Days
$426.40
Details

Top referenced anti-Laminin alpha 1 Antibodies

  1. Polyclonal Laminin alpha 1 Primary Antibody for IHC (fro), IHC (p) - ABIN540406 : McDaniel, Rumer, Biroc, Metz, Singh, Porter, Schedin: Remodeling of the mammary microenvironment after lactation promotes breast tumor cell metastasis. in The American journal of pathology 2006 (PubMed)
    Show all 3 Pubmed References

More Antibodies against Laminin alpha 1 Interaction Partners

Mouse (Murine) Laminin, alpha 1 (LAMA1) interaction partners

  1. laminin-1 does not have a positive effect on ENCC migration in HD mice on E12.5, in contrast to the phenomenon seen in normal mice gut (show GUSB Antibodies) specimens, where laminin-1 promotes ENCC migration during the same period.

  2. Altered LAMA1 expression in the aganglionic region may contribute to impaired ENCC migration, resulting in HD. These data could help in understanding the pathophysiologic interactions between LAMA1 and ENCC migration

  3. Laminin is instructive and CaMKII (show CAMK2G Antibodies) is non-permissive for the formation of complex aggregates of acetylcholine receptors on myotubes in culture.

  4. Laminin regulates PDGFRbeta cell differentiation, fate determination, cell stemness and muscle development via gpihbp1 (show GPIHBP1 Antibodies).

  5. while MMP-9 (show MMP9 Antibodies) is not essential for hypoxic-induced cerebral angiogenesis, it plays an important role in post-hypoxic vascular pruning by degrading laminin and claudin-5 (show CLDN5 Antibodies)

  6. interaction of alpha6beta1 in embryonic stem cells (ECCs) with laminin-1 activates alpha6beta1/CD151 (show CD151 Antibodies) signaling which programs ESCs (show NR2E3 Antibodies) toward the endothelial cells lineage fate

  7. These findings suggest that LAMA1 plays a critical role in kidney function and kidney aging by regulating the mesangial cell population and mesangial matrix deposition through TGF-beta (show TGFB1 Antibodies)/Smad (show SMAD1 Antibodies) signaling.

  8. Mutations in Lama1 allow developing retinal vessels to enter the vitreous where they anastomose with vessels of the hyaloid system which persist and expand

  9. Our data show that the absence of Lama1 has an impact on the Bergmann glia scaffold that aberrantly develops.

  10. Laminin alpha1 chain is not responsible for muscle disease in the mdx (show DMD Antibodies) mouse model for Duchenne muscular dystrophy (show DMD Antibodies)

Human Laminin, alpha 1 (LAMA1) interaction partners

  1. We report here a severe defect of neuromuscular transmission in a consanguineous patient with a homozygous variant in the laminin alpha-5 (show LAMA5 Antibodies) subunit gene (LAMA5 (show LAMA5 Antibodies)). The variant c.8046C>T (p.Arg2659Trp) is rare and has a predicted deleterious effect. The affected individual, who also carries a rare homozygous sequence variant in LAMA1, had muscle weakness, myopia, and facial tics

  2. LAMA1 SNP rs2089760 plays an important role in the development of PM.

  3. LAMA1 deficiency can lead to alteration in cytoskeletal dynamics, which may invariably lead to alteration in dendrite growth and axonal formation. Patient-derived fibroblasts have impaired adhesion, reduced migration, abnormal morphology and increased apoptosis due to impaired activation of Cdc42 (show CDC42 Antibodies), a member of the Rho family of GTPases that is involved in cytoskeletal dynamics.

  4. Sixteen novel LAMA1 variants were identified in fourteen families with Poretti-Boltshauser syndrome. The frameshift variant c.[2935delA] recurred in six unrelated families on a shared haplotype, suggesting a founder effect.

  5. Taken together, these findings suggest that miR (show MLXIP Antibodies)-202 may function as a novel tumor suppressor in ESCC by repressing cell proliferation and migration, and its biological effects may attribute the inhibition of LAMA1-mediated FAK (show PTK2 Antibodies)-PI3K (show PIK3CA Antibodies)-Akt (show AKT1 Antibodies) signaling.

  6. Our results indicate that invasion of cervical cancer is accomplished by the remodeling of the interstitial stroma, which process includes decrease and partial replacement of fibronectin (show FN1 Antibodies) and collagens by a laminin-rich matrix

  7. Novel PMCA3 missense mutation co-occurring with a heterozygous mutation in LAMA1 impaired cellular Ca2+ homeostasis in patients with Cerebellar Ataxia.

  8. Identification of biallelic mutations in LAMA1 as the cause of cerebellar dysplasia with cysts in seven affected individuals.

  9. Studies indicate that progenitor endothelial cells (ECs), endothelial colony-forming cells (ECFCs), deposit collagen IV (show COL4 Antibodies), fibronectin (show FN1 Antibodies), and laminin.

  10. miR (show MLXIP Antibodies)-9 negatively controls lamin A (show LMNA Antibodies) and progerin expression in neural cells.

Zebrafish Laminin, alpha 1 (LAMA1) interaction partners

  1. Through deletion analyses, the study established that lama1 expression in the anterior CNS and paraxial mesoderm is driven by an enhancer located within intron 1. Also, endogenous lama1 expression driven by the intronic enhancer is controlled by Hedgehog (show SHH Antibodies) signaling, possibly through Gli (show GLI1 Antibodies)/Zic (show ZIC1 Antibodies) binding sites within the lama1 intron 1 enhancer, in the paraxial mesoderm.

  2. Loss of lama1 leads to divergent effects on focal adhesion assembly in a spatiotemporally-specific manner. Laminin is required for multiple steps of optic cup morphogenesis, including optic stalk constriction, invagination, and formation of a spherical lens. In lama1(UW1) mutants, loss of epithelial polarity and altered adhesion lead to defective tissue architecture and formation of a disorganized retina.

  3. Analysis of zebrafish laminin-alpha 1 mutants reveals multiple functions for laminin-alpha 1 in the outgrowth and guidance of central nervous system axons

  4. Laminin alpha 1 is needed for lens development in zebrafish embryos.

  5. The phenotypic and genetic analyses of a recessive, larval lethal zebrafish mutant, bal(a69), characterized by severe eye defects and shortened body axis, is reported.

  6. two guidance cues, TAG-1 (show CNTN2 Antibodies) and laminin-alpha1, influence the behavior of growth cones during axon pathfinding in vivo

  7. tag1 (show CNTN2 Antibodies), lama1 and vangl2 (show VANGL2 Antibodies) participate in a common mechanism that integrates signaling between the FBMN and its environment to regulate migration.

Rabbit Laminin, alpha 1 (LAMA1) interaction partners

  1. The distribution of laminin and alphaSMA (show ACTA2 Antibodies) in the testis and epididymis might point out to their roles in the male reproduction.

Laminin alpha 1 (LAMA1) Antigen Profile

Protein Summary

Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.

Gene names and symbols associated with LAMA1

  • laminin, alpha 1 (Lama1) antibody
  • laminin subunit alpha 1 (LAMA1) antibody
  • laminin subunit alpha 1 (Lama1) antibody
  • laminin, alpha 1 (LAMA1) antibody
  • laminin, alpha 1 (lama1) antibody
  • laminin subunit alpha 1 (lama1) antibody
  • AA408497 antibody
  • LAMA antibody
  • LAMA1 antibody
  • S-LAM-alpha antibody

Protein level used designations for LAMA1

S-LAM alpha , S-laminin subunit alpha , laminin A chain , laminin subunit alpha-1 , laminin-1 subunit alpha , laminin-3 subunit alpha , laminin-1 , laminin, alpha 1 , bal , bashful , zmp:0000000656 , laminin subunit alpha-1-like

GENE ID SPECIES
16772 Mus musculus
284217 Homo sapiens
316758 Rattus norvegicus
374016 Gallus gallus
455302 Pan troglodytes
480201 Canis lupus familiaris
506387 Bos taurus
569971 Danio rerio
722472 Macaca mulatta
100059860 Equus caballus
100357482 Oryctolagus cuniculus
100403734 Callithrix jacchus
100465830 Ailuropoda melanoleuca
100563687 Anolis carolinensis
100625589 Sus scrofa
101083299 Felis catus
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