Lectin, Mannose-Binding, 1 (LMAN1) ELISA Kits

The protein encoded by LMAN1 is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. Additionally we are shipping LMAN1 Antibodies (51) and LMAN1 Proteins (7) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
LMAN1 3998 P49257
LMAN1 70361 Q9D0F3
LMAN1 116666 Q62902
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Top LMAN1 ELISA Kits at antibodies-online.com

Showing 3 out of 8 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 31 pg/mL 0.312-20 ng/mL   96 Tests Log in to see 2 to 3 Days
$779.90
Details
Rat < 0.38 ng/mL 0.625 ng/mL - 40 ng/mL   96 Tests Log in to see 11 to 18 Days
$589.86
Details
Mouse
  96 Tests Log in to see 15 to 18 Days
$946.00
Details

More ELISA Kits for LMAN1 Interaction Partners

Human Lectin, Mannose-Binding, 1 (LMAN1) interaction partners

  1. Combined deficiency of factors V and VIII by chance coinheritance of parahaemophilia and haemophilia A, but not by mutations of either LMAN1 or MCFD2 (show MCFD2 ELISA Kits)

  2. Genetic variants in the exon1 of MBL gene per se are not risk factors for Systemic lupus erythematosus (SLE) in South Indian Tamils. However, the association of codon 54 (rs1800450) with medium vessel vasculitis suggests that it may be a genetic modifier of clinical phenotype in SLE.

  3. Mannan-binding lectin (show MBL2 ELISA Kits) reduces CpG DNA-induced inflammatory cytokine production in monocytes.

  4. MMP-9 (show MMP9 ELISA Kits) secretion was reduced in the LMAN1 knockout cell line compared to control cells confirming the functional role of LMAN1.

  5. Authors identified a class of pathogen-derived ERGIC-53 ligands, a lectin-independent basis for their association with ERGIC-53, and a role for ERGIC-53 in the propagation of several highly pathogenic RNA virus families.

  6. Studies indicate that the LMAN1-CRD contains distinct, separable binding sites for both its partner protein MCFD2 (show MCFD2 ELISA Kits) and the cargo proteins FV/FVIII (show F8 ELISA Kits).

  7. Data indicate that together with its soluble coreceptor MCFD2 (show MCFD2 ELISA Kits), LMAN1 transports coagulation factors V (FV) and VIII (FVIII (show F8 ELISA Kits)).

  8. Mutations in LMAN1 lead to F5F8D (combined deficiency of factor V And factor VIII) due to alterations in LMAN1-MCFD2 (show MCFD2 ELISA Kits) complex of coat protein (show GOLPH3 ELISA Kits) (COP)II complex trafficking machinery; 70% of F5F8D patients have mutations in LMAN1. [REVIEW]

  9. UBXD1 modulates the trafficking of ERGIC-53-containing vesicles by controlling the interaction of transport factors with the cytoplasmic tail of ERGIC-53.

  10. Two new mutations at ERGIC-53 gene in a Turkish family.

Mouse (Murine) Lectin, Mannose-Binding, 1 (LMAN1) interaction partners

  1. LMAN1 may play a role in photoreceptor gene transport and homeostasis.

  2. Mice deficient in LMAN1 exhibit FV and FVIII deficiencies and liver accumulation of alpha1-antitrypsin.

  3. surfactant proteins A and D and mannose-binding lectin (show MBL2 ELISA Kits) play roles in inflammation caused by DNA in lungs and other tissues

  4. ERGIC-53 gene transcription is regulated in response to endoplasmic reticulum stress

LMAN1 Antigen Profile

Antigen Summary

The protein encoded by this gene is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. The protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in the gene are associated with a coagulation defect. Using positional cloning, the gene was identified as the disease gene leading to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished.

Gene names and symbols associated with LMAN1

  • lectin, mannose binding 1 (LMAN1) antibody
  • lectin, mannose-binding, 1 (Lman1) antibody
  • complexin 3 (cplx3) antibody
  • lectin, mannose-binding, 1 (lman1) antibody
  • lectin, mannose binding 1 (lman1) antibody
  • lectin, mannose binding 1 S homeolog (lman1.S) antibody
  • lectin, mannose binding 1 (Lman1) antibody
  • 2610020P13Rik antibody
  • AI326273 antibody
  • AU043785 antibody
  • C730041J05 antibody
  • cpx-iii antibody
  • cpxiii antibody
  • ERGIC-53 antibody
  • ERGIC53 antibody
  • F5F8D antibody
  • FMFD1 antibody
  • gp58 antibody
  • lman1 antibody
  • lman1-a antibody
  • MCFD1 antibody
  • MR60 antibody
  • p58 antibody
  • wu:fc54c09 antibody
  • wu:fi36e01 antibody
  • Xp58 antibody

Protein level used designations for LMAN1

ER-Golgi intermediate compartment 53 kDa protein , endoplasmic reticulum-golgi intermediate compartment protein 53 , intracellular mannose specific lectin , intracellular mannose-specific lectin MR60 , protein ERGIC-53 , lectin, mannose-binding, 1 , lectin mannose-binding 1 , fc54c09 , fi36e01 , protein ERGIC-53-like , ERGIC-53 protein , intracellular mannose specific lectin MR60 , LOW QUALITY PROTEIN: protein ERGIC-53

GENE ID SPECIES
3998 Homo sapiens
70361 Mus musculus
116666 Rattus norvegicus
426849 Gallus gallus
455448 Pan troglodytes
476186 Canis lupus familiaris
496634 Xenopus (Silurana) tropicalis
559775 Danio rerio
697449 Macaca mulatta
100021881 Monodelphis domestica
100354112 Oryctolagus cuniculus
100404326 Callithrix jacchus
100475249 Ailuropoda melanoleuca
100562643 Anolis carolinensis
100592766 Nomascus leucogenys
394295 Xenopus laevis
511649 Bos taurus
100728262 Cavia porcellus
Selected quality suppliers for LMAN1 (LMAN1) ELISA Kits
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