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LEPREL1 encodes a member of the prolyl 3-hydroxylase subfamily of 2-oxo-glutarate-dependent dioxygenases. Additionally we are shipping LEPREL1 Antibodies (17) and LEPREL1 Proteins (3) and many more products for this protein.
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This gene encodes a member of the prolyl 3-hydroxylase subfamily of 2-oxo-glutarate-dependent dioxygenases. These enzymes play a critical role in collagen chain assembly, stability and cross-linking by catalyzing post-translational 3-hydroxylation of proline residues. Mutations in this gene are associated with nonsyndromic severe myopia with cataract and vitreoretinal degeneration, and downregulation of this gene may play a role in breast cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
leprecan-like protein 1
, myxoid liposarcoma associated protein 4
, prolyl 3-hydroxylase 2
, myxoid liposarcoma-associated protein 4
, prolyl 3-hydroxylase 3