Leucine-Rich Repeat Containing G Protein-Coupled Receptor 4 (LGR4) ELISA Kits

G protein-coupled receptors (GPCRs) play key roles in a variety of physiologic functions. Additionally we are shipping LGR4 Antibodies (97) and LGR4 Proteins (7) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
LGR4 55366 Q9BXB1
LGR4 107515 A2ARI4
LGR4 286994 Q9Z2H4
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Top LGR4 ELISA Kits at antibodies-online.com

Showing 9 out of 17 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Delivery Price Details
Human 0.375 ng/mL 0.62 ng/mL - 40 ng/mL A typical standard curve 96 Tests 13 to 16 Days
$641.23
Details
Rat
  96 Tests 15 to 18 Days
$707.14
Details
Mouse
  96 Tests 11 to 18 Days
$618.29
Details
Rabbit
  96 Tests 15 to 18 Days
$707.14
Details
Pig
  96 Tests 15 to 18 Days
$707.14
Details
Goat
  96 Tests 15 to 18 Days
$707.14
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Guinea Pig
  96 Tests 15 to 18 Days
$707.14
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Monkey
  96 Tests 15 to 18 Days
$707.14
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Dog
  96 Tests 15 to 18 Days
$707.14
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More ELISA Kits for LGR4 Interaction Partners

Human Leucine-Rich Repeat Containing G Protein-Coupled Receptor 4 (LGR4) interaction partners

  1. High expression of LGR4 is associated with Primary intestinal-type carcinomas than diffuse tumours.

  2. The miR-193a-3p regulates osteoblast differentiation by modulating LGR4/ATF4 signaling and suggests that the miR-193a-3p/LGR4/ATF4 regulation axis may play an important role in regulating bone remodeling.

  3. findings support a crucial role of the Wnt signaling component LGR4 in breast cancer initiation, metastasis, and breast cancer stem cell.

  4. Loss of LGR4 abrogated RSPO3-regulated osteogenesis and RSPO3-induced ERK1/2 signalling inhibition.

  5. Luciferase reporter assay was performed to confirm that LGR4 is a direct target gene of miR-137 with a potential binding site in the 3'UTR of LGR4.

  6. the host protein leucine-rich repeat-containing G protein-coupled receptor 4 (Lgr4) is essential for VSV and VSV-G pseudotyped lentivirus (VSVG-LV) to infect susceptible cells.

  7. High LGR4 expression is associated with osteoarthritis.

  8. Data (including data from studies using transgenic/knockout mice) suggest that LGR4 is key protein necessary for prostate cancer epithelial-mesenchymal transition and metastasis; LGR4 expression is elevated in human prostate cancer cell lines with metastatic potential; LGR4 silencing in prostate cancer cell line impairs cell migration and invasion without affecting cell proliferation.

  9. LGR4 is another receptor for RANKL. LGR4 competes with RANK to bind RANKL and suppresses canonical RANK signaling during osteoclast differentiation.

  10. The LGR4 A750T variant is correlated with central obesity-related characteristics in young subjects.

  11. Lgr4 is a critical positive factor for skin tumorigenesis by mediating the activation of MEK1/ERK1/2 and Wnt/beta-catenin pathways.

  12. miR-34a gene expression upregulation inhibits ARPE-19 cell proliferation, migration and adhesion partly by suppressing LGR4 expression.

  13. Lgr4 activates Jmjd2a/AR signaling pathway to promote interaction AR with PSA promoter, causing reduction of prostate cancer apoptosis and cell cycle arrest.

  14. A mechanistic understanding of RANKL-LGR4 interaction has provided new insight into LGR4 mediated RANKL signaling in osteoporosis and other diseases

  15. miR-218 directly targets LGR4 and modulated the PI3K/Akt and Wnt/beta-catenin pathways in the LNCaP-IL-6+ cells.

  16. LGR4 promotes tumorigenesis of prostate cancer via PI3K/Akt signaling pathway.

  17. These findings suggest that aberrant RSPO3-LGR4 signaling potentially acts as a driving mechanism in the aggressiveness of Keap1-deficient lung ADs.

  18. the LGR4-Rspo1 complex crystal structure shows divergent mechanisms of ligand recognition by leucine-rich repeat G-protein-coupled receptors

  19. our results suggest a previously unknown Stat3-LGR4 molecular network, which may control osteosarcoma development and progression

  20. RSPO-LGR4 not only induces the clearance of RNF43/ZNRF3 to increase Wnt receptor levels but also recruits IQGAP1 into the Wnt signaling complex.

Mouse (Murine) Leucine-Rich Repeat Containing G Protein-Coupled Receptor 4 (LGR4) interaction partners

  1. findings support a crucial role of the Wnt signaling component LGR4 in breast cancer initiation, metastasis, and breast cancer stem cell.

  2. These results shed new light on the role of Rspo3 in heart development and demonstrate that LGR4 is the principal R-spondin 3 receptor in the heart.

  3. he HA tag-specific antibody can be employed to characterize the biochemical features of Lgr4 and to identify possible biding partners of the protein in cells derived from various mouse tissues.

  4. LGR4 might play a vital role in stem cells from apical papillae proliferation and odontoblastic differentiation.

  5. compressive force induced the differentiation of RAW264.7 from increase in RANK and decrease in LGR4 expression.

  6. Rspo3-LGR4 axis protects hepatocytes from hypoxia/reoxygenation injury via activating beta-catenin.

  7. the host protein leucine-rich repeat-containing G protein-coupled receptor 4 (Lgr4) is essential for VSV and VSV-G pseudotyped lentivirus (VSVG-LV) to infect susceptible cells.

  8. Data (including data from studies using transgenic/knockout mice) suggest that LGR4 is key protein necessary for prostate cancer epithelial-mesenchymal transition and metastasis; LGR4 expression is elevated in human prostate cancer cell lines with metastatic potential; LGR4 silencing in prostate cancer cell line impairs cell migration and invasion without affecting cell proliferation.

  9. LGR4 is another receptor for RANKL. LGR4 competes with RANK to bind RANKL and suppresses canonical RANK signaling during osteoclast differentiation. Both whole-body (Lgr4(-/-)) and monocyte conditional knockout mice of Lgr4 (Lgr4 CKO) exhibit osteoclast hyperactivation (including elevation of osteoclast number, surface area, and size) and increased bone erosion.

  10. Lgr4 is a critical positive factor for skin tumorigenesis by mediating the activation of MEK1/ERK1/2 and Wnt/beta-catenin pathways.

  11. RSPO-LGR4/5-ZNRF3/RNF43 module controls metabolic liver zonation and is a hepatic growth/size rheostat during development, homeostasis and regeneration.

  12. These date indicate that hydrogen peroxide suppresses Lgr4 expression in osteoblastic cells.

  13. Lgr4 gene is regulated by BMP and is required for BMP effects on osteoblastic differentiation.

  14. Rspo1 and its receptor of leucine-rich repeat containing G-protein-coupled receptor 4 (Lgr4) should be a novel molecular signal in the transmission of mechanical stimuli to biological signal in the bone, and this signal should be in the upstream of Wnt/beta-catenin signaling for bone formation.

  15. Study suggests that miR-34c contributes to osteoclast differentiation by targeting LGR4, providing novel insights into understanding the molecular mechanism underlying osteoclast differentiation.

  16. A mechanistic understanding of RANKL-LGR4 interaction has provided new insight into LGR4 mediated RANKL signaling in osteoporosis and other diseases

  17. LGR4 acted as a key receptor for Rspo2 to promote osteogenesis.

  18. Lgr4 is critical for ovarian somatic cell specialization via the cooperative signaling of Rspo1 and Wnt/beta-catenin

  19. results suggest that the deletion of Lgr4 can lead to premature cataract formation, as well as progressive deterioration with aging.

  20. The endogenously expressed Lgr4 may act as an antagonist molecule that helps to fine-tune the R-spondin/norrin-mediated Lgr4-Wnt signaling during gonadal development.

LGR4 Antigen Profile

Antigen Summary

G protein-coupled receptors (GPCRs) play key roles in a variety of physiologic functions. Members of the leucine-rich GPCR (LGR) family, such as GPR48, have multiple N-terminal leucine-rich repeats (LRRs) and a 7-transmembrane domain (Weng et al., 2008

Gene names and symbols associated with LGR4

  • leucine rich repeat containing G protein-coupled receptor 4 (LGR4) antibody
  • leucine-rich repeat-containing G protein-coupled receptor 4 (Lgr4) antibody
  • 9130225G07 antibody
  • A330106J01Rik antibody
  • A930009A08Rik antibody
  • BNMD17 antibody
  • Gpr48 antibody

Protein level used designations for LGR4

G protein-coupled receptor 48 , leucine-rich repeat-containing G-protein coupled receptor 4 , G protein-coupled receptor GPR48 , G-protein coupled receptor 48

GENE ID SPECIES
55366 Homo sapiens
451088 Pan troglodytes
107515 Mus musculus
286994 Rattus norvegicus
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