Lipase, Endothelial (LIPG) ELISA Kits

Human Lipase, Endothelial (LIPG) interaction partners

1. In this study, the authors show that endothelial lipase (LIPG) is aberrantly overexpressed in basal-like triple-negative breast cancer. They demonstrate that LIPG is required for in vivo tumorigenicity and metastasis of triple-negative breast cancer cells.

2. Hepatic overexpression of endothelial lipase lowers high-density lipoprotein but maintains reverse cholesterol transport via SR-BI/ABCA1-dependent pathways.

3. The differences in serum lipid profiles between the Maonan and Han populations might partly be attributed to LIPG SNPs, their haplotypes and gene-environmental interactions.

4. the LIPG polymorphism (584 C/T) - CAD correlation study in Turkish people living in Turkey. Results of this study suggest that the CC genotype may be a genetic risk factor for CAD and carrying T allele may be protective against CAD.

5. We identified a missense Asn396Ser mutation (rs77960347) in the endothelial lipase (LIPG) gene, occurring with an allele frequency of 1% in the general population, which was significantly associated with depressive symptoms (P-value=5.2 x 10-08, beta=7.2).

6. the EL 2237 A allele might be associated with an increased Apo A1 level in Coronary Artery Disease subjects.

7. Increased hepatic expression of endothelial lipase attenuates cholesterol diet-induced hypercholesterolemia and protects against atherosclerosis.

8. Endothelial lipase is upregulated in human umbilical vein endothelial cells by interleukin-6 partly via the p38 MAPK and p65 NF-kappaB signaling pathways.

9. Endothelial lipase (EL) 2037T/C and 2237 G/A polymorphisms might not affect the lipid-owing effects of rosuvastatin in Chinese coronary artery disease patients

10. Endothelial lipase protein expression was increased in skeletal muscle of middle-aged men with high oxygen consumption.

11. LIPG Polymorphisms are associated with Hyperlipidemia.

12. FoxA1, FoxA2, and LIPG control the uptake of extracellular lipids for breast cancer growth.

13. results suggested that the SNP -384A/C in the LIPG gene may be associated with risk for coronary artery disease(CAD)and the LIPG gene may play a role in CAD in the Han Chinese

14. Studied if a specific variant of the endothelial lipase gene was more specifically linked to the severity of diabetic retinopathy.

15. Several lipid-related gene polymorphisms interact with overweight/obesity to modulate blood pressure levels.

16. EL-384A/C polymorphism was significantly associated with the ACS and lipids profile in an elderly Uygur population in Xinjiang.

17. Results showed that the protein levels of endothelial lipase (EL), NF-kappaB p65, MAPK p38 protein levels, in addition to the proliferation of umbilical vein endothelial cells (HUVECs), were increased by angiotensin II (AngII).

18. Genetic studies of patients with early onset of coronary artery disease (CAD) in the Chinese Han population show that the EL 584C/T variant is not always involved in the pathogenesis of early-onset CAD.

19. The results of the present meta-analysis suggest that the carriers of EL 584 T allele have a higher HDL-C level in Caucasian populations. Whereas, it might not be a protective factor for CHD.

20. Results indicate the spatial consensus catalytic triad "Ser-Asp-His", a characteristic motif in lipoprotein lipase, hepatic lipase, and endothelial lipase.

Pig (Porcine) Lipase, Endothelial (LIPG) interaction partners

1. Brain capillary endothelial cells synthesize and secrete endothelial lipase (EL); EL can generate fatty acids at blood-brain barrier for transport to deeper regions of the brain as building blocks for membrane phospholipids.

Mouse (Murine) Lipase, Endothelial (LIPG) interaction partners

1. FoxA1, FoxA2, and LIPG control the uptake of extracellular lipids for breast cancer growth.

2. inhibitory activity of AOE on pancreatic lipase enzyme was evaluated at concentrations from 60 to 1000 mug/mL. The AOE inhibited the pancreatic lipase with an IC50 = 588.5 mug/mL

3. Hepatic lipase and endothelial lipase influence molecular species of several classes of plasma lipids.

4. Furin has a role as the primary in vivo convertase of ANGPTL3 and endothelial lipase in hepatocytes

5. The role of EL in HDL-associated S1P effects provides new insights into EL action, the responses seen through EL and HDL interaction, and S1P signaling.

6. Endothelial lipase may act as an alternative candidate to provide fatty acids to the heart and regulate cardiac function.

7. Hepatic lipase- and endothelial lipase-deficiency in mice promotes macrophage-to-feces RCT and HDL antioxidant properties.

8. Endothelial lipase supplies cells with free fatty acids and HDL-derived lysophosphatidylcholine and lysophosphatidylethanolamine species resulting in increased cellular triglycerides and phosphatidylcholine (PC) content and decreased PC synthesis.

9. EL expression modulates vascular remodeling as well as plasma HDL-C levels

10. Starvation regulates endothelial lipase expression via SREBP-2.

11. Endothelial lipase plays a role in thyroid and adipocyte biology in addition to its well-known role in endothelial function and HDL metabolism.

12. DEHP exposure did not influence lipase activity, whereas it slightly enhanced UGT activity and exclusively increased CYP4A14 levels in pregnant and/or postpartum dams.

13. targeted disruption of EL increased HDL particles with preserved anti-inflammatory and anti-atherosclerotic functions

14. Statins can reduce EL expression in vitro and in vivo via inhibition of RhoA activity. The inhibition of EL expression in the vessel wall may contribute to the anti-atherogenic effects of statins.

15. The additive effect of hepatic lipase and EL on HDL metabolism but not macrophage reverse cholesterol transport in mice.

16. Data show that endothelial lipase (EL) was upregulated in rat atherosclerosis and taht lipopolysaccharide stimulates EL expression in vitro through NFkappaB activation.

17. Endothelial lipase has a role in HDL metabolism [review]

18. endothelial lipase has a role in regulating HDL levels

19. endothelial lipase has a role in regulating HDL cholesterol levels

20. EL is a major determinant of HDL concentration, structure, and metabolism in mice