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The protein encoded by LIPG has substantial phospholipase activity and may be involved in lipoprotein metabolism and vascular biology.
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Human LIPG ELISA Kit for Sandwich ELISA - ABIN414389
Ben-Zeev, Hosseini, Lai, Ehrhardt, Wong, Cefalù, Noto, Averna, Doolittle, Péterfy: Lipase maturation factor 1 is required for endothelial lipase activity. in Journal of lipid research 2011
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We identified a missense Asn396Ser mutation (rs77960347) in the endothelial lipase (LIPG) gene, occurring with an allele frequency of 1% in the general population, which was significantly associated with depressive symptoms (P-value=5.2 x 10-08, beta=7.2).
the EL 2237 A allele might be associated with an increased Apo (show C9orf3 ELISA Kits) A1 level in Coronary Artery Disease subjects.
Increased hepatic expression of endothelial lipase attenuates cholesterol diet-induced hypercholesterolemia and protects against atherosclerosis.
Endothelial lipase is upregulated in human umbilical vein endothelial cells by interleukin-6 (show IL6 ELISA Kits) partly via the p38 MAPK (show MAPK14 ELISA Kits) and p65 NF-kappaB (show NFkBP65 ELISA Kits) signaling pathways.
Endothelial lipase (EL) 2037T/C and 2237 G/A polymorphisms might not affect the lipid-owing effects of rosuvastatin in Chinese coronary artery disease patients
Endothelial lipase protein (show ABHD6 ELISA Kits) expression was increased in skeletal muscle of middle-aged men with high oxygen consumption.
LIPG Polymorphisms are associated with Hyperlipidemia.
FoxA1, FoxA2 (show FOXA2 ELISA Kits), and LIPG control the uptake of extracellular lipids for breast cancer growth.
results suggested that the SNP -384A/C in the LIPG gene may be associated with risk for coronary artery disease(CAD)and the LIPG gene may play a role in CAD in the Han Chinese
Studied if a specific variant of the endothelial lipase gene was more specifically linked to the severity of diabetic retinopathy.
Brain capillary endothelial cells synthesize and secrete endothelial lipase (EL); EL can generate fatty acids at blood-brain barrier for transport to deeper regions of the brain as building blocks for membrane phospholipids.
inhibitory activity of AOE on pancreatic lipase (show PNLIP ELISA Kits) enzyme was evaluated at concentrations from 60 to 1000 mug/mL. The AOE inhibited the pancreatic lipase (show PNLIP ELISA Kits) with an IC50 = 588.5 mug/mL
Hepatic lipase (show LIPC ELISA Kits) and endothelial lipase influence molecular species of several classes of plasma lipids.
Furin (show FURIN ELISA Kits) has a role as the primary in vivo convertase of ANGPTL3 (show ANGPTL3 ELISA Kits) and endothelial lipase in hepatocytes
The role of EL in HDL-associated S1P effects provides new insights into EL action, the responses seen through EL and HDL interaction, and S1P signaling.
Endothelial lipase may act as an alternative candidate to provide fatty acids to the heart and regulate cardiac function.
Hepatic lipase (show LIPC ELISA Kits)- and endothelial lipase-deficiency in mice promotes macrophage-to-feces RCT (show FOXE3 ELISA Kits) and HDL (show HSD11B1 ELISA Kits) antioxidant properties.
Endothelial lipase supplies cells with free fatty acids and HDL (show HSD11B1 ELISA Kits)-derived lysophosphatidylcholine and lysophosphatidylethanolamine species resulting in increased cellular triglycerides and phosphatidylcholine (show SGMS2 ELISA Kits) (PC) content and decreased PC synthesis.
EL expression modulates vascular remodeling as well as plasma HDL (show HSD11B1 ELISA Kits)-C levels
Starvation regulates endothelial lipase expression via SREBP-2 (show SREBF2 ELISA Kits).
The protein encoded by this gene has substantial phospholipase activity and may be involved in lipoprotein metabolism and vascular biology. This protein is designated a member of the TG lipase family by its sequence and characteristic lid region which provides substrate specificity for enzymes of the TG lipase family.
, lipase, endothelial
, endothelial lipase-like
, Endothelial lipase
, endothelial cell-derived lipase
, lipoprotein lipase H
, lipose, endothelial
, endothelial-derived lipase
, lipase G