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LIPH encodes a membrane-bound member of the mammalian triglyceride lipase family. Additionally we are shipping LIPH Kits (18) and LIPH Proteins (9) and many more products for this protein.
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We finally isolate control and Enpp2 (show ENPP2 Antibodies)-null dermal pipilla precursors and identify the expression and upregulation of LIPH, an alternative LPA (show LPA Antibodies)-producing enzyme, suggesting that this gene could functionally compensate for the absence of Enpp2 (show ENPP2 Antibodies).
Novel sequence variants in the LIPH (show LIPC Antibodies) and LPAR6 (show LPAR6 Antibodies) genes underlies autosomal recessive woolly hair/hypotrichosis in three consanguineous Pakistani families.
The present study shows 93% of Japanese patients with ARWH had at least one of the two founder mutations in exon 6 of LIPH (show LIPC Antibodies). Highly prevalent founder mutations in LIPH (show LIPC Antibodies).
The authors report no apparent decrease in total hair count but remarkable miniaturization and increased telogen/anagen hair ratio in patients homozygous mutations in LIPH (show LIPC Antibodies).
This meta-analysis demonstrates that the T allele in the LIPC (show LIPC Antibodies) rs493258 polymorphism was significantly associated with the risk of any and late age related macular degeneration
Our data suggest that LIPH (show LIPC Antibodies) may have prognostic value for esophageal cancer.
sequencing LIPH (show LIPC Antibodies) identi fi ed a novel non-sense mutation (c.328C>T; p.Arg110*) in one and a previously reported 2-bp deletion mutation (c.659_660delTA, p.Ile220ArgfsX29) in three other families.
A heterozygous missense mutation c.736T>A (p.Cys246Ser) in exon 6 of the LIPH (show LIPC Antibodies) gene of both the affected individuals was identified. In addition, we also found that both patients carried heterozygous sequences in exon 5 of the LIPH (show LIPC Antibodies) gene.
The study further extends the body of evidence that sequence variants in the LIPH (show LIPC Antibodies) gene result in hypotrichosis and woolly hair phenotype.
High LIPH (show LIPC Antibodies) expression is associated with metastasis in breast cancer.
Mutation patterns of LIPH (show LIPC Antibodies) might be associated with hypotrichosis severity in autosomal recessive woolly hair/hypotrichosis.
Results show the LIPH mode of action and confirm the crucial role of LIPH in hair production.
association between a deletion of a single nucleotide in LIPH exon and rex phenotype
This gene encodes a membrane-bound member of the mammalian triglyceride lipase family. It catalyzes the production of 2-acyl lysophosphatidic acid (LPA), which is a lipid mediator with diverse biological properties that include platelet aggregation, smooth muscle contraction, and stimulation of cell proliferation and motility.
, lipase member H
, LPD lipase-related protein
, mPA-PLA1 alpha
, membrane-associated phosphatidic acid-selective phospholipase A1-alpha
, membrane-bound phosphatidic acid-selective phospholipase A1
, phospholipase A1 member B
, lacrimal lipase