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LEAP2 is a cysteine-rich cationic antimicrobial peptide (Krause et al., 2003 [PubMed 12493837]).[supplied by OMIM, Mar 2008].. Additionally we are shipping LEAP2 Antibodies (13) and LEAP2 Proteins (3) and many more products for this protein.
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Human LEAP2 ELISA Kit for Sandwich ELISA - ABIN843630
Razali, Abdul Aziz, Lim, Mat Junit: Investigation into the effects of antioxidant-rich extract of Tamarindus indica leaf on antioxidant enzyme activities, oxidative stress and gene expression profiles in HepG2 cells. in PeerJ 2015
We identified the amphibian leap2 gene which is highly related to its mammalian orthologues at both structural and sequence levels. The gene is expressed in the embryo mostly in the endoderm-derived tissues. Accordingly it is induced in pluripotent animal cap cells by FGF, activin or a combination of vegT/beta-catenin.
LEAP-2 displays antimicrobial activity against bacteria and yeasts.
These results show that the secondary structure of human LEAP-2 has a profound impact on its antibacterial activity.
Data suggest that LEAP-2 is not involved in the physiological response of GI epithelia to iron, nor is it mitogenic for epithelial cells or chemotactic for THP-1 monocytes.
report the full-length cDNA sequences of porcine hepcidin and liver-expressed antimicrobial peptide-2 (LEAP-2)
LEAP2 is a cysteine-rich cationic antimicrobial peptide (Krause et al., 2003
liver expressed antimicrobial peptide 2
, liver-expressed antimicrobial peptide 2
, liver-expressed antimicrobial protein 2