Ly6/neurotoxin 1 Proteins (LYNX1)

LYNX1 encodes a member of the Ly-6/neurotoxin gene family, a group of lymphocyte antigens that attach to the cell surface by a glycosylphosphatidylinositol anchor and have a unique structure showing conserved 8-10 cysteine residues with a characteristic spacing pattern. Additionally we are shipping Ly6/neurotoxin 1 Antibodies (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
LYNX1 23936 Q9WVC2
LYNX1 66004 Q9BZG9
Rat LYNX1 LYNX1 300018  
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Top Ly6/neurotoxin 1 Proteins at antibodies-online.com

Showing 6 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$6,869.04
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$6,869.04
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see Available
$814.00
Details
Yeast REACT_Squirrel Monkey His tag   1 mg Log in to see 60 to 71 Days
$2,091.83
Details
Yeast Chimpanzee His tag   1 mg Log in to see 60 to 71 Days
$2,091.83
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Yeast Cow His tag   1 mg Log in to see 60 to 71 Days
$2,091.83
Details

LYNX1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human ,
,

More Proteins for Ly6/neurotoxin 1 (LYNX1) Interaction Partners

Mouse (Murine) Ly6/neurotoxin 1 (LYNX1) interaction partners

  1. The results of this study suggested greater spine loss as a better correlate of elevated functional plasticity in adult Lynx1-KO mice.

  2. tPA (show PLAT Proteins) activity in V1 can be unmasked following 4 d of monocular deprivation when mice older than 2 months are raised in standard cages by the genetic removal of Lynx1, a negative regulator of adult plasticity.

  3. lynx1 KO animals over 1 year of age have clear ultrastructural differences in the striatum.

  4. Lynx1 has a role in shifting alpha4beta2 nicotinic receptor subunit stoichiometry by affecting assembly in the endoplasmic reticulum

  5. study identified an increase in expression of Lynx1 protein that prevented plasticity in the primary visual cortex late in life; Lynx1 expression maintains stability of mature cortical networks in the presence of cholinergic innervation

  6. Results show that lynx1 colocalizes with nAChRs on CNS neurons and physically associates with nAChRs and enhances receptor desensitization, resulting in a novel type of functional modulation

Human Ly6/neurotoxin 1 (LYNX1) interaction partners

  1. results show that some functional and behavioral aspects of alpha6-nAChRs are modulated by lynx1

  2. These findings provide new insights into the acetylcholine receptor (show CHRNA1 Proteins)-mediated regulatory mechanism of SLURP-2 expression in keratinocytes.

  3. These studies suggest that lynx1 is a potential target both for development of drugs that may limit lung cancer growth as well as for drugs that may be effective for asthma or COPD (show ARCN1 Proteins) treatment.

  4. This epigenome-wide DNA methylation (show HELLS Proteins) analysis in postmortem hippocampus and prefrontal cortex specimens confirmed LYNX1 DNA methylation (show HELLS Proteins) profiles in major depression.

  5. Micromolar affinities and fast washout rates measured for ws-LYNX1 and its mutants are in contrast to nanomolar affinities and irreversibility of binding for alpha-bungarotoxin and similar snake alpha-neurotoxins also targeting alpha7 nAChR (show CHRNA7 Proteins).

  6. Computer modeling, based on ws-LYNX1 NMR structure and AChBP x-ray structure, revealed a possible mode of ws-LYNX1 binding.

  7. LY-6K (show Ly6k Proteins),a novel member protein of the Ly-6/uPAR (show PLAUR Proteins) superfamily, is a significant new molecular marker for diagnosis and gene therapy in patients with breast cancer.

  8. decreased Lynx1 is associated with squamous cell lung carcinoma

  9. LY-6K (show Ly6k Proteins) meaningfully participates in breast cancer cell metastasis

Rhesus Monkey Ly6/neurotoxin 1 (LYNX1) interaction partners

  1. Lynx1 appears to act as a negative modulator of alpha7 nAChR (show CHRNA7 Proteins)-induced events by inhibiting Src (show SRC Proteins) activation.

Ly6/neurotoxin 1 (LYNX1) Protein Profile

Protein Summary

This gene encodes a member of the Ly-6/neurotoxin gene family, a group of lymphocyte antigens that attach to the cell surface by a glycosylphosphatidylinositol anchor and have a unique structure showing conserved 8-10 cysteine residues with a characteristic spacing pattern. Functional analysis indicates that this protein is not a ligand or neurotransmitter but has the capacity to enhance nicotinic acetylcholine receptor function in the presence of acetylcholine. This gene may also play a role in the pathogenesis of psoriasis vulgaris. Alternatively spliced variants encoding different isoforms have been identified.

Gene names and symbols associated with Ly6/neurotoxin 1 Proteins (LYNX1)

  • Ly6/neurotoxin 1 (Lynx1)
  • Ly6/neurotoxin 1 (LYNX1)
  • AI838844 protein
  • SLURP-2 protein
  • SLURP2 protein

Protein level used designations for Ly6/neurotoxin 1 Proteins (LYNX1)

GC26 , ly-6/neurotoxin-like protein 1 , secreted Ly-6/uPAR domain-containing protein 2 , secreted Ly-6/uPAR-related protein 2 , Ly-6 neurotoxin-like protein 1 , SLURP-2 , secreted Ly6/uPAR related protein 2

GENE ID SPECIES
23936 Mus musculus
66004 Homo sapiens
300018 Rattus norvegicus
464434 Pan troglodytes
516158 Bos taurus
574359 Macaca mulatta
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