anti-Lymphocyte-Specific Protein 1 (LSP1) Antibodies

LSP1 encodes an intracellular F-actin binding protein. Additionally we are shipping LSP1 Proteins (9) and LSP1 Kits (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
LSP1 16985 P19973
LSP1 4046 P33241
LSP1 361680  
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Top anti-LSP1 Antibodies at antibodies-online.com

Showing 10 out of 199 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated FACS, IHC (p), WB LSP1 Antibody (Center) (ABIN651634) western blot analysis in MCF-7 cell line lysates (35 µg/lane). This demonstrates the LSP1 antibody detected the LSP1 protein (arrow). LSP1 Antibody (Center) (ABIN651634) immunohistochemistry analysis in formalin fixed and paraffin embedded human lymph tissue followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10 to 11 Days
$385.00
Details
Dog Rabbit Un-conjugated IHC, WB Rabbit Anti-LSP1 Antibody Catalog Number: AVARP00014_P050 Formalin Fixed Paraffin Embedded Tissue: Human heart Tissue Observed Staining: Cytoplasmic Primary Antibody Concentration: 1:100 Other Working Concentrations: N/A Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0.5 - 2.0 sec WB Suggested Anti-LSP1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Positive Control: OVCAR-3 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated ELISA, WB   100 μg Log in to see 6 to 7 Days
$429.84
Details
Human Goat Un-conjugated ELISA, WB   100 μg Log in to see 6 to 7 Days
$429.84
Details
Human Rabbit Un-conjugated IHC, WB Immunohistochemistry of paraffin-embedded Human adenomyosis using LSP1 antibody at dilution of 1:100 (x400 lens). 100 μL Log in to see 16 Days
$366.77
Details
Dog Goat Un-conjugated ELISA, IHC, IHC (p), WB 50 μg Log in to see 11 to 14 Days
$484.00
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: LSP1 Antibody [NBP1-86852] - Staining of human cell line U-251MG shows positivity in plasma membrane & golgi apparatus. Immunohistochemistry-Paraffin: LSP1 Antibody [NBP1-86852] - Staining of human spleen shows cytoplasmic positivity in cells of red and white pulp. 0.1 mL Log in to see 10 to 13 Days
$494.38
Details
Dog Rabbit Un-conjugated WB 50 μg Log in to see 11 to 14 Days
$551.83
Details
Cow Goat Un-conjugated ELISA, WB 100 μg Log in to see 11 to 14 Days
$610.50
Details
Human Goat Un-conjugated ELISA, WB Western Blot: LSP1 Antibody [NBP1-52017] (1ug/ml) staining of Peripheral Blood Lymphocytes lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 7 to 9 Days
$488.73
Details

Top referenced anti-LSP1 Antibodies

  1. Human Polyclonal LSP1 Primary Antibody for WB - ABIN2801907 : Jongstra-Bilen, Young, Chong, Jongstra: Human and mouse LSP1 genes code for highly conserved phosphoproteins. in Journal of immunology (Baltimore, Md. : 1950) 1990 (PubMed)
    Show all 4 Pubmed References

  2. Human Polyclonal LSP1 Primary Antibody for ELISA, WB - ABIN4331781 : Gringhuis, den Dunnen, Litjens, van der Vlist, Geijtenbeek: Carbohydrate-specific signaling through the DC-SIGN signalosome tailors immunity to Mycobacterium tuberculosis, HIV-1 and Helicobacter pylori. in Nature immunology 2009 (PubMed)
    Show all 2 Pubmed References

  3. Human Polyclonal LSP1 Primary Antibody for ELISA, WB - ABIN4331782 : Liu, Cara, Kaur, Raharjo, Mullaly, Jongstra-Bilen, Jongstra, Kubes: LSP1 is an endothelial gatekeeper of leukocyte transendothelial migration. in The Journal of experimental medicine 2005 (PubMed)
    Show all 2 Pubmed References

  4. Human Monoclonal LSP1 Primary Antibody for ELISA, WB - ABIN531846 : Gringhuis, Kaptein, Wevers, Mesman, Geijtenbeek: Fucose-specific DC-SIGN signalling directs T helper cell type-2 responses via IKK?- and CYLD-dependent Bcl3 activation. in Nature communications 2014 (PubMed)

  5. Human Polyclonal LSP1 Primary Antibody for IHC, IHC (p) - ABIN4331785 : Johansson, Tabor, Wikell, Jalkanen, Fuxe: TGF-β1-Induced Epithelial-Mesenchymal Transition Promotes Monocyte/Macrophage Properties in Breast Cancer Cells. in Frontiers in oncology 2015 (PubMed)

More Antibodies against LSP1 Interaction Partners

Mouse (Murine) Lymphocyte-Specific Protein 1 (LSP1) interaction partners

  1. Regulation of O-GlcNAcylation and phosphorylation of lymphocyte-specific protein-1 (Lsp1) is a key switch that triggers apoptosis in activated B cells. O-GlcNAcylation at S209 of Lsp1 is a prerequisite for the recruitment of its kinase, PKC-beta1, to induce S243 phosphorylation.

  2. the LSP1-myosin1e bimolecular complex plays a pivotal role in the regulation of actin cytoskeleton remodeling during Fc gamma receptor-driven phagocytosis.

  3. the importance of LSP1 Copy number variations and LSP1 insufficiency in the pathogenesis of rheumatoid arthritis, is reported.

  4. Data indicate that in lymphocyte specific 1 protein (LSP1)-deficient mice, PECAM-1 expression was reduced in endothelial cells, but not in neutrophils.

  5. functions as a negative regulator of proliferation and migration in liver

  6. TRAF1 and LSP1 cooperate downstream of 4-1BB to activate ERK signaling and down-modulate the levels of Bim leading to enhanced T cell survival.

  7. Endothelial LSP1 participates in leukocyte adhesion in vitro, and leukocyte adhesion, through ICAM-1, fosters the activation of endothelial LSP1.

  8. LSP1 plays an important role in leukocyte recruitment induced by both KC and MIP-2.

  9. Data demonstrate that endothelial LSP1 is recruited to the cytoskeleton in inflammation and plays an important role in forming endothelial domes thereby regulating neutrophil transendothelial migration.

  10. Lsp1 negatively regulates fMLP-induced polarization and chemotaxis of neutrophils during inflammation through its function on adhesion via specific integrins, such as Mac-1 (CD11b/CD18).

  11. The results show a complex function of LSP1 in regulating leukocyte recruitment to inflamed sites.

  12. MK2-regulated LSP1 phosphorylation is involved in stabilization of F-actin polarization during neutrophil chemotaxis.

  13. These results demonstrate that the absence of LSP1 promotes healing of skin wounds.

  14. the absence of LSP1 promotes fibrosis in the skin

Human Lymphocyte-Specific Protein 1 (LSP1) interaction partners

  1. LSP1 rs3817198 T > C polymorphism is associated with increased risk of breast cancer, especially in Caucasian and Asian populations [meta-analysis]

  2. These results show that LSP1 is critical regulator of actomyosin contractility in primary macrophages.

  3. Underexpression of LSP1 is associated with Breast Cancer Recurrence.

  4. LSP1 rs569550 and rs592373 polymorphisms are both risk factors for breast cancer.

  5. the importance of LSP1 Copy number variations and LSP1 insufficiency in the pathogenesis of rheumatoid arthritis, is reported.

  6. The breast cancer SNP LSP1 rs3817198 was associated with an increased risk of lung cancer (odds ratio: 1.10) This association was strongest for women with adenocarcinoma (P = 1.2x10(-4)).

  7. Data indicate that slit2N alters the localization and binding of Robo1 to WASp and LSP1 in HIV-1-gp120-treated immature dendritic cells (iDCs).

  8. Single nucleotide polymorphism in LSP1 is associated with breast cancer.

  9. The LSP1 rs3817198T>C polymorphism is a low-penetrant risk factor for developing breast cancer but may not be in Africans.

  10. Low-risk variants of LSP1 is associated with familial breast cancer.

  11. The LSP1 and 2q35 SNPs appear to interact multiplicatively on breast cancer risk for BRCA2 mutation carriers.

  12. LSP1 interacts with F-actin and the cytoskeleton through residues downstream of amino acid residue 230. The cytoskeleton binding site of mouse LSP1 maps to the 300-330 interval.

  13. Leukocyte-specific protein 1 is a cytoskeletal targeting protein for the ERK/MAP kinase pathway

  14. LSP1 protein facilitates virus transport into the proteasome after its interaction with DC-SIGN through its interaction with cytoskeletal proteins.

  15. MK2-regulated LSP1 phosphorylation is involved in stabilization of F-actin polarization during neutrophil chemotaxis.

  16. DC-SIGN was constitutively associated with a signalosome complex consisting of the scaffold proteins LSP1, KSR1 and CNK and the kinase Raf-1

LSP1 Antigen Profile

Protein Summary

This gene encodes an intracellular F-actin binding protein. The protein is expressed in lymphocytes, neutrophils, macrophages, and endothelium and may regulate neutrophil motility, adhesion to fibrinogen matrix proteins, and transendothelial migration. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene names and symbols associated with LSP1

  • lymphocyte-specific protein 1 (LSP1) antibody
  • lymphocyte-specific protein 1 L homeolog (lsp1.L) antibody
  • lymphocyte specific 1 (Lsp1) antibody
  • lymphocyte-specific protein 1 (Lsp1) antibody
  • Lsp-1 antibody
  • LSP1 antibody
  • p50 antibody
  • pp52 antibody
  • WP34 antibody

Protein level used designations for LSP1

lymphocyte-specific protein 1 , lymphocyte-specific protein 1, isoform 3 , 52 kDa phosphoprotein , S37 protein , leukocyte specific protein 1 , leukocyte-specific protein 1 , lymphocyte-specific antigen WP34 , 47 kDa actin binding protein , 47 kDa actin-binding protein , F-actin binding and cytoskeleton associated protein , leufactin (leukocyte F-actin binding protein) , 1 BAC CH230-300K22 (Children's Hospital Oakland Research Institute) complete , lymphocyte specific 1

GENE ID SPECIES
100137571 Papio anubis
100158343 Xenopus laevis
16985 Mus musculus
4046 Homo sapiens
361680 Rattus norvegicus
611553 Canis lupus familiaris
374254 Gallus gallus
508832 Bos taurus
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