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LPCAT2 encodes a member of the lysophospholipid acyltransferase family. Additionally we are shipping LPCAT2 Antibodies (55) and LPCAT2 Proteins (10) and many more products for this protein.
Showing 5 out of 19 products:
Mouse (Murine) LPCAT2 ELISA Kit for Sandwich ELISA - ABIN429447
Ahn, Jung, Kwon, Song: Alteration of Lysophosphatidylcholine-Related Metabolic Parameters in the Plasma of Mice with Experimental Sepsis. in Inflammation 2016
three of these five genes (CXCL14 (show CXCL14 ELISA Kits), ITGAX (show ITGAX ELISA Kits), and LPCAT2) harbored polymorphisms associated with aggressive disease development in a human GWAS cohort consisting of 1,172 prostate cancer patients.
Data indicate a strong negative correlation between ALOX15 (show ALOX15 ELISA Kits), FADS2 (show FADS2 ELISA Kits), and IL5RA (show IL5RA ELISA Kits) expression with 2-arachidonoylglycerophosphocholine levels in dual asthmatic responses.
LPCAT1 (show LPCAT1 ELISA Kits) and -2 have, in addition to their known function in specialized cells, a ubiquitous role in LD-associated lipid metabolism
Our enzymatic assays strongly suggest that the cDNA previously identified as LPCAT2/lyso platelet-activating factor-acetyltransferase cDNA has AGPAT activity and thus we prefer to identify this clone as AGPAT11 as well.
The enzyme acetyl-CoA:LYSO-PAF acetyltransferase catalyzes not only biosynthesis of PAF upon acute inflammatory stimula (show PAF ELISA Kits)tion but also (show PAF ELISA Kits)incorporation of arachidonoyl-CoA to produce PAF precursor (show PAF ELISA Kits) membrane glycerophospholipids for membrane biogenesis.
Selected compounds competed with acetyl-CoA (show LPCAT1 ELISA Kits) for the inhibition of LPCAT2 lyso-PAFAT activity and suppressed PAF (show PAF ELISA Kits) biosynthesis in mouse peritoneal macrophages stimulated with a calcium ionophore. These compounds had low inhibitory effects on LPCAT1 (show LPCAT1 ELISA Kits) activity, indicating that adverse effects on respiratory functions may be avoided.
LPCAT2 was detected in wild-type spinal cord microglia, and the absence of LPCAT2 expression precluded spinal platelet-activating factor expression in LPCAT2-knockout mice.
We show a new signaling pathway for rapid biosynthesis of PAF (show PAF ELISA Kits) that is mediated by phosphorylation of LPCAT2 at Ser (show SIGLEC1 ELISA Kits)-34.
Specific inhibition of the PAF (show PAF ELISA Kits) biosynthetic activity by phosphorylated LPCAT2 will provide a novel target for the regulation of inflammatory disorders.
Cloned the mouse acetyl-CoA:LYSO-PAF acetyltransferase (show LPCAT1 ELISA Kits) and found that the enzyme catalyzed not only biosynthesis of PAF (show PAF ELISA Kits) from lyso-PAF (show PAF ELISA Kits) but also incorporation of arachidonoyl-CoA to produce PAF (show PAF ELISA Kits) precursor membrane glycerophospholipids.
This gene encodes a member of the lysophospholipid acyltransferase family. The encoded enzyme may function in two ways: to catalyze the biosynthesis of platelet-activating factor (1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine) from 1-O-alkyl-sn-glycero-3-phosphocholine, and to catalyze the synthesis of glycerophospholipid precursors from arachidonyl-CoA and lysophosphatidylcholine. The encoded protein may function in membrane biogenesis and production of platelet-activating factor in inflammatory cells. The enzyme may localize to the endoplasmic reticulum and the Golgi.
, 1-alkylglycerophosphocholine O-acetyltransferase
, LPC acyltransferase 2
, acetyl-CoA:lyso-PAF acetyltransferase
, acetyl-CoA:lyso-platelet-activating factor acetyltransferase
, acyl-CoA:lysophosphatidylcholine acyltransferase 2
, acyltransferase like 1
, acyltransferase-like 1
, lyso-PAF acetyltransferase
, lyso-platelet-activating factor (PAF) acetyltransferase
, lysoPC acyltransferase 2
, acyl-CoA:lysophosphatidylcholine acyltransferase member 1
, acyltransferase like 1A
, lysophosphatidylcholine acyltransferase 2
, Lysophosphatidylcholine acyltransferase 2
, acyltransferase-like 1-A