Lysosomal Protein Transmembrane 5 Proteins (LAPTM5)

LAPTM5 encodes a transmembrane receptor that is associated with lysosomes. Additionally we are shipping LAPTM5 Antibodies (25) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
LAPTM5 7805 Q13571
LAPTM5 16792 Q61168
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Top LAPTM5 Proteins at

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 50 to 55 Days
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 50 to 55 Days
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see Available

LAPTM5 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)

More Proteins for Lysosomal Protein Transmembrane 5 (LAPTM5) Interaction Partners

Human Lysosomal Protein Transmembrane 5 (LAPTM5) interaction partners

  1. These findings suggest that the inactivation of LAPTM5 may contribute to tumorigenesis in a subset of human cancers

  2. Taken together, our results suggested that decreased LAPTM5 inhibited proliferation and viability, as well as induced G0/G1 cell cycle arrest possibly via deactivation of ERK1/2 and p38 (show CRK Proteins) in BCa (show BLNK Proteins) cells

  3. Insufficient expression of LAPTM5 may take part in the pathogenesis of systemic lupus erythematosus (SLE) and contribute to the severity of the disease, none of LAPTM5 polymorphisms contributes significantly to SLE susceptibility in a Chinese population.

  4. The interaction of LAPTM5 with CD1e (show CD1e Proteins) and their colocalization in antigen processing compartments both suggest that LAPTM5 might influence the role of CD1e (show CD1e Proteins) in the presentation of lipid antigens.

  5. LAPTM5 is a substrate of the ITCH-mediated degradation and its protein level is negatively regulated by ITCH

  6. LAPTM5-mediated programmed cell death is closely associated with the spontaneous regression of neuroblastomas

  7. LAPTM5 shows stage-specific expression during B cell differentiation. It may be involved in B cell malignancies.

Mouse (Murine) Lysosomal Protein Transmembrane 5 (LAPTM5) interaction partners

  1. these results suggest that CD3zeta can be degraded by two pathways: SLAP/c-Cbl, which targets internalized cell surface CD3zeta dependent on TCR signaling, and LAPTM5, which targets intracellular CD3zeta independent of TCR signaling.

  2. the pre-BCR (show BCR Proteins) induces the downmodulation of its own expression through induction of LAPTM5, which promotes the lysosomal transport and degradation of the intracellular pre-BCR (show BCR Proteins) pool and limits the supply of pre-BCR (show BCR Proteins) to the cell surface

  3. LAPTM5 acts as a positive modulator of inflammatory signaling pathways and hence cytokine secretion in macrophages

  4. LAPTM5 physically interacts with the B cell receptor complex and promotes its degradation in the lysosomal compartment in mouse B cells.

  5. the lysosomal protein LAPTM5 negatively regulated surface TCR expression by specifically interacting with the invariant signal-transducing CD3zeta chain (show CD247 Proteins) and promoting its degradation

LAPTM5 Protein Profile

Protein Summary

This gene encodes a transmembrane receptor that is associated with lysosomes. The encoded protein, also known as E3 protein, may play a role in hematopoiesis.

Gene names and symbols associated with LAPTM5

  • lysosomal-associated protein transmembrane 5 (LOC100151049)
  • lysosomal protein transmembrane 5 (LAPTM5)
  • lysosomal-associated protein transmembrane 5 (Laptm5)
  • CLAST6 protein
  • E3 protein
  • HA1520 protein

Protein level used designations for LAPTM5

lysosomal protein transmembrane 5 , CD40-ligand-activated specific transcripts , human retinoic acid-inducible E3 protein , lysosomal associated multispanning membrane protein 5 , lysosomal multispanning membrane protein 5 , lysosomal-associated multitransmembrane protein 5 , lysosomal-associated transmembrane protein 5 , retinoic acid-inducible E3 protein , lysosomal-associated multispanning membrane protein 5

100151049 Danio rerio
100349164 Oryctolagus cuniculus
7805 Homo sapiens
512361 Bos taurus
16792 Mus musculus
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