anti-Lysyl Oxidase-Like 4 (LOXL4) Antibodies

Mouse (Murine) Lysyl Oxidase-Like 4 (LOXL4) interaction partners

1. These results demonstrate that weak LOXL4 expression leads to remodeling of the extracellular matrix through induction of collagen synthesis, deposition, and structural changes.

Human Lysyl Oxidase-Like 4 (LOXL4) interaction partners

1. The data demonstrate a novel function of LOXL4 in tumor metastasis mediated by exosomes through regulation of the FAK/Src pathway and angiogenesis in hepatocellular carcinoma.

2. trans-suppression of host CDH3 and LOXL4 genes in cultured human intestinal epithelial cells following C. parvum infection involves nuclear delivery of parasite Cdg7_FLc_1000 RNA

3. LOXL1, LOXL3, and LOXL4 expressions are associated with distant metastasis of gastric cancer.

4. Our study suggests lack of association between DNA polymorphisms rs2236479 of COL18A1 and rs2862296 of LOXL-4 with advanced POP [pelvic organ prolapse] in this population [Brazil].

5. study describes for the first time a direct link between a retinoic-induced gene and protein, LOXL4, and its general clinical pro-healing properties in ECM dynamics

6. Although expression of LOXL4 is not statistically associated with neck metastases, we showed that LOXL4 expression significantly increased in laryngeal cancer.

7. In hepatocellular carcinoma, low LOXL4 expression was associated with lower overall survival rates and higher cumulative recurrence rates.

8. These results provide a set of the essential genes in this newly identified miR-193a-3p/LOXL4/Oxidative Stress axis.

9. High Lysyl oxidase-like 4 promotes proliferation and metastasis of gastric cancer via FAK/Src pathway.

10. data suggest that abnormal expression of LOXL4 of KCOT may enhance angiogenesis in KCOT, which may help to promote the locally aggressive biological behavior of KCOT.

11. TGF-beta1 induced injured MCL to express more LOXs than injured ACL (up to 1.85-fold in LOX, 2.21-fold in LOXL-1, 1.71-fold in LOXL-2, 2.52-fold in LOXL-3 and 3.32-fold in LOXL-4).

12. Alternatively spliced lysyl oxidase-like 4 isoforms have a pro-metastatic role in cancer.

13. The human lysyl oxidase-like 4 gene does not confer increased genotypic risk for adolescent idiopathic scoliosis.

14. SNPs in the lysyl oxidase-like protein 4 and complement component 3 genes are associated with increased risk for endometriosis and endometriosis-associated infertility in a Puerto Rican population.

15. Overexpression of the lysyl oxidase-like 4 gene is associated with metastatic head/neck carcinoma.

16. The data presented in this work might emphasize the involvement of LOXL4 in molecular processes of the genesis or progression of head and neck carcinomas.

17. LOXL4, with the four scavenger receptor cysteine rich domains, may also function as an active amine oxidase

18. Up-regulation of lysyl oxidase mRNA and protein expression is associated with oral squamous cell carcinoma

19. LOXL4-DC stimulated T cells produce higher IFN-gamma secretion compared to unstimulated T cells and T cells stimulated with untransfected DCs, in the presence of the pan-DR-epitope (PADRE)

20. These results suggest that LOXL4 may function as a negative feedback regulator of TGF-beta1 in cell invasion by inhibiting the metabolism of extracellular matrix (ECM) components.

Cow (Bovine) Lysyl Oxidase-Like 4 (LOXL4) interaction partners

1. These results suggest that TGF-beta1-dependent expression of LOXL4 plays a role in vascular extracellular matrix homeostasis, contributing to vascular processes associated with extracellular matrix remodeling and fibrosis.