anti-MAP/microtubule Affinity-Regulating Kinase 3 (MARK3) Antibodies

The protein encoded by MARK3 is activated by phosphorylation and in turn is involved in the phosphorylation of tau proteins MAP2 and MAP4. Additionally we are shipping MAP/microtubule Affinity-Regulating Kinase 3 Proteins (12) and MAP/microtubule Affinity-Regulating Kinase 3 Kits (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MARK3 4140 P27448
MARK3 17169 Q03141
MARK3 170577 Q8VHF0
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Top anti-MAP/microtubule Affinity-Regulating Kinase 3 Antibodies at antibodies-online.com

Showing 10 out of 120 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-MARK3 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: 293T cell lysate Sample Type: Lane1 = 10ug mouse brain extract, Lane 2 = 50ug mouse brain extractPrimary Antibody Dilution: Anti-MARK3 1:2500Submitted By: Dr. Veronique Dorval, Laval University 100 μL 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated FACS, IHC, ELISA, WB 100 μg 11 to 16 Days
$469.05
Details
Chicken Rabbit Un-conjugated IC, IF, IHC, WB Immunofluorescent analysis of MARK3 staining in HeLa cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a hidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of MARK3 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugad compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL 13 to 14 Days
$487.50
Details
Mouse Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from HeLa/293 cells, using MARK3 Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using MARK3 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated ELISA, ICC, IF, IHC, WB ABIN6274214 at 1/100 staining Human liver cancer tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. Western blot analysis of extracts from mouse brain, using MARK3 antibody. 100 μL 11 to 12 Days
$390.77
Details
Human Mouse Un-conjugated ELISA, FACS, IHC, IHC (p) 100 μg 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, IF, IHC, WB Western Blot (WB) analysis of specific cells using C-TAK1 Polyclonal Antibody. 100 μL Available
$363.46
Details
Human Rabbit Un-conjugated ELISA, IHC, IHC (p), WB Anti-MARK3 antibody IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN959348 concentration 10 ug/ml. 50 μL 11 to 14 Days
$484.00
Details
Cow Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$551.83
Details
Human Sheep Un-conjugated IP, WB 0.25 mg 6 to 8 Days
$467.50
Details

Top referenced anti-MAP/microtubule Affinity-Regulating Kinase 3 Antibodies

  1. Human Polyclonal MARK3 Primary Antibody for IHC (p), ELISA - ABIN543014 : Sun, Lu, Feng, Reinhard, Jan, Fantl, Williams: PAR-1 is a Dishevelled-associated kinase and a positive regulator of Wnt signalling. in Nature cell biology 2001 (PubMed)
    Show all 3 Pubmed References

  2. Human Monoclonal MARK3 Primary Antibody for FACS, IHC - ABIN1098125 : Schwarz, Murphy, Sohn, Mansky: C-TAK1 interacts with microphthalmia-associated transcription factor, Mitf, but not the related family member Tfe3. in Biochemical and biophysical research communications 2010 (PubMed)
    Show all 2 Pubmed References

  3. Human Polyclonal MARK3 Primary Antibody for IP, WB - ABIN550350 : Ogg, Gabrielli, Piwnica-Worms: Purification of a serine kinase that associates with and phosphorylates human Cdc25C on serine 216. in The Journal of biological chemistry 1994 (PubMed)
    Show all 3 Pubmed References

More Antibodies against MAP/microtubule Affinity-Regulating Kinase 3 Interaction Partners

Human MAP/microtubule Affinity-Regulating Kinase 3 (MARK3) interaction partners

  1. Authors identified a regulatory switch controlled by MARK3 that couples microtubules to the actin cytoskeleton to establish epithelial cell polarity through ARHGEF2.

  2. findings indicate that brain PP-1I associates with and is regulated by the associated protein kinases C-TAK1 and PFTK1

  3. We have shown that serum ALP levels modified the association of MARK3 with bone mineral density in osetoporosis for Chinese patients.

  4. interaction between Mitf and C-TAK1 was demonstrated.

  5. results show that LKB1 can direct the phosphorylation of the serine-threonine kinase PAR1A

  6. identify sequence motifs required for stable C-TAK1 association and substrate phosphorylation

  7. The C-TAK1/p78 constitutively associates with and phosphorylates KSR1 generating a 14-3-3 binding site.

  8. Data show that the protein kinase Cdc25 C-associated kinase 1 (C-TAK1) is a binding partner and a substrate of Pim-1, and suggest a role for Pim-1 as a positive regulator at the G(2)/M transition of the cell cycle.

  9. 14-3-3 binding to MARK3 is dependent on phosphorylation.

  10. Class IIa histone deacetylases (HDACs) are subjected to signal-independent nuclear export that relies on their constitutive phosphorylation. EMK and C-TAK1, are identified as regulators of this process.

  11. identify a molecular mechanism through which the hMARK3 UBA domain has evolved to bind the kinase domain

  12. occurrence of an unusual TG 3' splice site in intron 3

Mouse (Murine) MAP/microtubule Affinity-Regulating Kinase 3 (MARK3) interaction partners

  1. Knockout mice were protected against high-fat diet-induced obesity and displayed attenuated weight gain, complete resistance to hepatic steatosis, and improved glucose handling with decreased insulin secretion.

  2. Approximately 50 additional residues preceding the previously defined KA1 domain are required for MARK3 proper folding.

Xenopus laevis MAP/microtubule Affinity-Regulating Kinase 3 (MARK3) interaction partners

  1. PAR-1 RNA rescues neural cell markers in embryos in which noncanonical Wnt signaling has been blocked. Novel roles for Wnt11R and PAR-1 were identified in neural cell specification. An unexpected connection was shown between morphogenesis and cell fate.

  2. PAR-1 is a crucial regulator of the balance between symmetric (two superficial daughters) and asymmetric (one superficial and one deep daughter) cell divisions

MAP/microtubule Affinity-Regulating Kinase 3 (MARK3) Antigen Profile

Protein Summary

The protein encoded by this gene is activated by phosphorylation and in turn is involved in the phosphorylation of tau proteins MAP2 and MAP4. Several transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with MARK3

  • microtubule affinity regulating kinase 3 (MARK3) antibody
  • MAP/microtubule affinity-regulating kinase 3b (mark3b) antibody
  • microtubule affinity regulating kinase 3 (mark3) antibody
  • MAP/microtubule affinity regulating kinase 3 (Mark3) antibody
  • microtubule affinity regulating kinase 3 (Mark3) antibody
  • MAP/microtubule affinity-regulating kinase 3a (mark3a) antibody
  • microtubule affinity regulating kinase 3 L homeolog (mark3.L) antibody
  • 1600015G02Rik antibody
  • A430080F22Rik antibody
  • c-tak1 antibody
  • ctak1 antibody
  • emk-2 antibody
  • Emk2 antibody
  • ETK-1 antibody
  • ETK1 antibody
  • fi39g08 antibody
  • KP78 antibody
  • MARK3 antibody
  • MPK10 antibody
  • par-1 antibody
  • Par-1a antibody
  • par1 antibody
  • PAR1A antibody
  • wu:fi39g08 antibody
  • zgc:55693 antibody
  • zgc:152848 antibody

Protein level used designations for MARK3

MAP/microtubule affinity-regulating kinase 3 , DKEYP-50F7.6 , MAP/microtubule affinity-regulating kinase 3-like , C-TAK1 , ELKL motif kinase 2 , EMK-2 , cdc25C-associated protein kinase 1 , protein kinase STK10 , ser/Thr protein kinase PAR-1 , serine/threonine-protein kinase p78 , EMK2/MARK3 serine-threonine protein kinase , MPK-10 , Ser/Thr protein kinase PAR-1A

GENE ID SPECIES
453184 Pan troglodytes
534872 Bos taurus
611285 Canis lupus familiaris
767634 Danio rerio
100219055 Taeniopygia guttata
100329119 Xenopus (Silurana) tropicalis
4140 Homo sapiens
17169 Mus musculus
170577 Rattus norvegicus
334300 Danio rerio
399395 Xenopus laevis
423480 Gallus gallus
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