MARK3 antibody (N-Term)

Catalog No. ABIN6258273

Product Details anti-MARK3 Antibody

Target: MARK3 (MAP/microtubule Affinity-Regulating Kinase 3 (MARK3))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MARK3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: MARK3 Antibody detects endogenous levels of total MARK3.

Predicted Reactivity: Pig,Rabbit,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human MARK3, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for MARK3

Target: MARK3 (MAP/microtubule Affinity-Regulating Kinase 3 (MARK3))

Alternative Name: MARK3 (MARK3 Products)

Synonyms: MARK3 antibody, par1 antibody, par-1 antibody, Par-1A antibody, CTAK1 antibody, KP78 antibody, PAR1A antibody, Par-1a antibody, 1600015G02Rik antibody, A430080F22Rik antibody, C-TAK1 antibody, ETK-1 antibody, ETK1 antibody, Emk2 antibody, MPK10 antibody, fi39g08 antibody, wu:fi39g08 antibody, zgc:152848 antibody, zgc:55693 antibody, c-tak1 antibody, ctak1 antibody, emk-2 antibody, microtubule affinity regulating kinase 3 antibody, MAP/microtubule affinity-regulating kinase 3b antibody, MAP/microtubule affinity regulating kinase 3 antibody, MAP/microtubule affinity-regulating kinase 3a antibody, microtubule affinity regulating kinase 3 L homeolog antibody, MARK3 antibody, mark3b antibody, mark3 antibody, Mark3 antibody, mark3a antibody, mark3.L antibody

Background:

Description: Involved in the specific phosphorylation of microtubule-associated proteins for tau, MAP2 and MAP4. Phosphorylates CDC25C on 'Ser-216'. Regulates localization and activity of some histone deacetylases by mediating phosphorylation of HDAC7, promoting subsequent interaction between HDAC7 and 14-3-3 and export from the nucleus (PubMed:16980613). Negatively regulates the Hippo signaling pathway and antagonizes the phosphorylation of LATS1. Cooperates with DLG5 to inhibit the kinase activity of STK3/MST2 toward LATS1 (PubMed:28087714).

Gene: MARK3

Molecular Weight: 85 kDa

Gene ID: 4140

UniProt: P27448

Pathways: SARS-CoV-2 Protein Interactome