anti-MAX Dimerization Protein 1 (MXD1) Antibodies

MXD1 encodes a member of the MYC/MAX/MAD network of basic helix-loop-helix leucine zipper transcription factors. Additionally we are shipping MXD1 Kits (26) and MXD1 Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MXD1 4084 Q05195
MXD1 17119  
MXD1 362391  
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Top anti-MXD1 Antibodies at antibodies-online.com

Showing 10 out of 50 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-MXD1 Antibody Titration:  0.2-1 ug/ml  Positive Control:  Human Muscle 100 μL 2 to 3 Days
$319.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-Mxd1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:1562500 Positive Control: Mouse Spleen 100 μL 2 to 3 Days
$319.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-Mxd1 Antibody Titration: 1.0 ug/ml Positive Control: Mouse Liver 100 μL 2 to 3 Days
$289.00
Details
Bat Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$581.17
Details
Bat Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$551.83
Details
Cow Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$581.17
Details
Human Mouse Un-conjugated ELISA 100 μg 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated WB Western blot analysis in CEM cell line lysates (35ug/lane). 400 μL 2 to 3 Days
$515.63
Details
Human Rabbit Un-conjugated WB Western blot analysis of extracts of HL-60 cells, using MXD1 antibody (ABIN1873789) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 90s. 100 μL 11 to 13 Days
$366.77
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of Mad using anti-Mad antibody .  Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each  Lane was loaded with 50ug of sample under reducing conditions.   Lane 1: rat testis tissue lysates, Lane 2: mouse ovary tissue lysates.  After Electrophoresis, proteins were transferred to a Nitrocellulose membrane at 150mA for 50-90 minutes. Blocked the membrane with 5% Non-fat Milk/ TBS for 1.5 hour at RT. The membrane was incubated with rabbit anti-Mad antigen affinity purified polyclonal antibody (Catalog # ) at 0.5 µg/mL overnight at 4°C, then washed with TBS-0.1%Tween 3 times with 5 minutes each and probed with a goat anti-rabbit IgG-HRP secondary antibody at a dilution of 1:10000 for 1.5 hour at RT. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit (Catalog # EK1002) with Tanon 5200 system. A specific band was detected for Mad at approximately 28KD. The expected band size for Mad is at 25KD. 100 μg 4 to 6 Days
$240.00
Details

Top referenced anti-MXD1 Antibodies

  1. Human Monoclonal MXD1 Primary Antibody for ChIP, IP - ABIN5563970 : Ullius, Lüscher-Firzlaff, Costa, Walsemann, Forst, Gusmao, Kapelle, Kleine, Kremmer, Vervoorts, Lüscher: The interaction of MYC with the trithorax protein ASH2L promotes gene transcription by regulating H3K27 modification. in Nucleic acids research 2014 (PubMed)

More Antibodies against MXD1 Interaction Partners

Human MAX Dimerization Protein 1 (MXD1) interaction partners

  1. these data show that MXD1 functions as a negative regulator of BCR-ABL1 expression and subsequently inhibits proliferation and sensitizes chronic myeloid leukemia cells to imatinib treatment

  2. Results suggest a role for MAX dimerization protein 1 (MXD1) in the control of ribosome biogenesis.

  3. Study revealed that HIF-1alpha-induced Mxd1 contributes to cisplatin-resistance in hypoxic osteosarcoma cells by directly repressing PTEN, which leads to the activation of PI3K/AKT antiapoptotic and survival pathway.

  4. the miR-382-5p/MXD1 axis plays a critical role in myelopoiesis by affecting the lineage choice of CD34(+) hematopoietic stem/progenitor cells.

  5. TCP10L stabilizes MAD1 protein level through direct interaction, and they cooperatively regulate cell cycle progression.

  6. down regulation of miR-202 increased the expression of its target Mxd1, followed by Mxd1 recruitment to the Sin3A repressor complex and through its dimerization with Max, and increased repression of Myc-Max target proteins.

  7. miR-17-92 cluster members miR-19a/b facilitated gastric cancer cell migration, invasion and metastasis through targeting the antagonist of c-Myc -- MXD1.

  8. This study suggests that genetic variants of MXD1 may modulate the effect of smoking on carotid plaque burden.

  9. Mad1 gene transfer inhibits the proliferation of human melanoma cells

  10. HBP1 and Mad1 repressors bind the Sin3 corepressor PAH2 domain with opposite helical orientations

  11. MAD1 and Proto-Oncogene Proteins c-myc reciprocally regulate ribosomal DNA transcription, providing a mechanism for coordination of ribosome biogenesis and cell growth

  12. c-myc and mad1 can regulate the hTERT transcript in a different manner in hTERT positive cells, but not in normal cells

  13. Mad1, Mxi1 and Rox genes were expressed and displayed mutations in haematological malignancies.

  14. This study provides a direct link between the growth factor signaling pathways regulated by PI3 kinase/Akt and MAP kinases with Myc-mediated transcription.

  15. TGF-beta can override Myc activity despite a stabilizing cancer mutation and induce senescence in myeloid tumor cells, at least in part by induction of Mad1

  16. examination of functionality of basic domains compared with Myc

  17. X-ray structures of Myc-Max and Mad-Max recognizing DNA. Molecular bases of regulation by proto-oncogenic transcription factors.

  18. Mad expression and Id2 down-regulation are important events during the TGF-beta cytostatic program in epithelial cells.

  19. Max as a novel co-activator of C/EBPalpha functions, thereby suggesting a possible link between C/EBPalpha and Myc-Max-Mad network.

  20. The PTEN tumor suppressor gene is a target of MAD1.

Mouse (Murine) MAX Dimerization Protein 1 (MXD1) interaction partners

  1. 1,25D and the VDR regulate the c-MYC/MXD1 network to suppress c-MYC function, providing a molecular basis for cancer preventive actions of vitamin D.

  2. Phe-7 is the critical determinant and provides the molecular specificity for the association between Sin3 and Mad in regulating cell growth and differentiation.

  3. Mad1 is a transcriptional repressor of Bcl-6.

MXD1 Antigen Profile

Protein Summary

This gene encodes a member of the MYC/MAX/MAD network of basic helix-loop-helix leucine zipper transcription factors. The MYC/MAX/MAD transcription factors mediate cellular proliferation, differentiation and apoptosis. The encoded protein antagonizes MYC-mediated transcriptional activation of target genes by competing for the binding partner MAX and recruiting repressor complexes containing histone deacetylases. Mutations in this gene may play a role in acute leukemia, and the encoded protein is a potential tumor suppressor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene names and symbols associated with MXD1

  • MAX dimerization protein 1 (MXD1) antibody
  • MAX dimerization protein 1 (mxd1) antibody
  • MAX dimerization protein 1 L homeolog (mxd1.L) antibody
  • MAX dimerization protein 1 (Mxd1) antibody
  • max dimerization protein 1 (Mxd1) antibody
  • AW122478 antibody
  • BHLHC58 antibody
  • Mad antibody
  • Mad-1 antibody
  • Mad1 antibody
  • MXD1 antibody
  • si:dkey-202n14.4 antibody
  • xmad1 antibody

Protein level used designations for MXD1

MAX dimerization protein 1 , Mad1 , MAD protein , max dimerization protein 1 , max dimerizer 1 , MAX-binding protein , antagonizer of myc transcriptional activity

GENE ID SPECIES
470395 Pan troglodytes
701784 Macaca mulatta
570082 Danio rerio
779097 Xenopus laevis
426299 Gallus gallus
4084 Homo sapiens
612631 Canis lupus familiaris
514626 Bos taurus
17119 Mus musculus
362391 Rattus norvegicus
100356271 Oryctolagus cuniculus
100726750 Cavia porcellus
100625349 Sus scrofa
101106754 Ovis aries
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