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MXD1 Products

(MAX Dimerization Protein 1 (MXD1))
This gene encodes a member of the MYC/MAX/MAD network of basic helix-loop-helix leucine zipper transcription factors. The MYC/MAX/MAD transcription factors mediate cellular proliferation, differentiation and apoptosis. The encoded protein antagonizes MYC-mediated transcriptional activation of target genes by competing for the binding partner MAX and recruiting repressor complexes containing histone deacetylases. Mutations in this gene may play a role in acute leukemia, and the encoded protein is a potential tumor suppressor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2011].

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Featured MXD1 Categories

MXD1 Antibodies

High quality antibodies with extensive validation data.

MXD1 ELISA Kits

Reliable ELISA kits for a wide range of species.

MXD1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended MXD1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN1539192
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
  • (1)
Cat. No. ABIN599397
Quantity 100 μg
Datasheet Datasheet
Reactivity Cow, Mouse, Rabbit
Application WB
Validations
  • (1)
Cat. No. ABIN6746140
Quantity 100 μL
Datasheet Datasheet

Recommended MXD1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6968513
Quantity 96 tests
Datasheet Datasheet
Reactivity Cow
Analytical Method Quantitative
Validations
Cat. No. ABIN993783
Quantity 96 tests
Datasheet Datasheet
Reactivity Dog
Analytical Method Quantitative
Validations
Cat. No. ABIN993782
Quantity 96 tests
Datasheet Datasheet

Recommended MXD1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3083269
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3134323
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1311684
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our MXD1 products

Ullius, Lüscher-Firzlaff, Costa, Walsemann, Forst, Gusmao, Kapelle, Kleine, Kremmer, Vervoorts, Lüscher: "The interaction of MYC with the trithorax protein ASH2L promotes gene transcription by regulating H3K27 modification." in: Nucleic acids research, Vol. 42, Issue 11, pp. 6901-20, (2014) (PubMed).

Sandhu, Volinia, Costinean, Galasso, Neinast, Santhanam, Parthun, Perrotti, Marcucci, Garzon, Croce: "miR-155 targets histone deacetylase 4 (HDAC4) and impairs transcriptional activity of B-cell lymphoma 6 (BCL6) in the E?-miR-155 transgenic mouse model." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 49, pp. 20047-52, (2012) (PubMed).

Synonyms and alternative names related to MXD1

MAX dimerization protein 1 (MXD1), MAX dimerization protein 1 (mxd1), MAX dimerization protein 1 L homeolog (mxd1.L), MAX dimerization protein 1 (Mxd1), max dimerization protein 1 (Mxd1), AW122478, BHLHC58, MAD, Mad, Mad-1, MAD1, Mad1, MXD1, si:dkey-202n14.4, xmad1

Protein level used designations for MXD1

  • MAX dimerization protein 1
  • Mad1
  • MAD protein
  • max dimerization protein 1
  • max dimerizer 1
  • MAX-binding protein
  • antagonizer of myc transcriptional activity
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