anti-Maelstrom Spermatogenic Transposon Silencer (MAEL) Antibodies

Plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization, which is essential for the germline integrity. Additionally we are shipping MAEL Kits (6) and MAEL Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MAEL 84944 Q96JY0
MAEL 98558 Q8BVN9
MAEL 364039  
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Top anti-MAEL Antibodies at antibodies-online.com

Showing 10 out of 11 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB   0.1 mg Log in to see 8 to 11 Days
$474.10
Details
Human Rabbit Un-conjugated ELISA, ICC, IF, WB Immunocytochemistry/Immunofluorescence: MAEL Antibody [NBP1-77139] - Immunofluorescence of Maelstrom in HeLa cells with Maelstrom antibody at 20 ug/mL. Western Blot: MAEL Antibody [NBP1-77139] - HeLa cell lysate with MAEL antibody at 1 ug/mL. 0.1 mg Log in to see 8 to 11 Days
$485.88
Details
Human Rabbit Un-conjugated IHC, IHC (p) Immunohistochemistry: MAEL Antibody  - Immunohistochemical staining of human testis shows moderate cytoplasmic positivity in cells in seminiferous ducts. 100 μL Log in to see 10 to 13 Days
$491.63
Details
Human Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, ICC, WB Immunocytochemical staining of HeLa cells with MAEL polyclonal antibody  at 5 ug/mL dilution. Western blot analysis of HeLa cells with MAEL polyclonal antibody  at 1 ug/mL dilution. 100 μg Log in to see 11 to 12 Days
$355.73
Details
Human Rabbit Un-conjugated IC, IF, ELISA, WB   100 μg Log in to see 11 to 16 Days
$578.29
Details
Human Rabbit HRP ELISA   100 μg Log in to see 11 to 18 Days
$412.19
Details
Human Rabbit FITC ELISA   100 μg Log in to see 11 to 18 Days
$412.19
Details
Human Rabbit Biotin ELISA   100 μg Log in to see 11 to 18 Days
$412.19
Details
Human Rabbit Un-conjugated ELISA, IHC   100 μg Log in to see 11 to 18 Days
$412.19
Details

MAEL Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , ,


, ,
Mouse (Murine)


Rat (Rattus)


More Antibodies against MAEL Interaction Partners

Human Maelstrom Spermatogenic Transposon Silencer (MAEL) interaction partners

  1. Report found that Mael is activated in proliferating cancer cells, where it serves to maintain genetic stability. Its depletion results in an increase in reactive oxygen species, followed by apoptosis or senescence.

  2. Data suggest that overexpression of MAEL, caused by gene amplification and/or decreased miR (show MLXIP Antibodies)-186, has a critical oncogenic role in UCB pathogenesis by downregulation of MTSS1 (show MTSS1 Antibodies).

  3. Study demonstrated that MAEL interacts with Snail (show SNAI1 Antibodies) and inhibit E-cadherin (show CDH1 Antibodies) promoter activity. MAEL is an oncogene (show RAB1A Antibodies) that plays an important role in the development and progression of colon cancer.

  4. Immunofluorescence analysis showed that MAEL co-localizes with the stress granule marker PABPC1 (show PABPC1 Antibodies) in stress granules during oxidative stress. MAEL may be involved in miRNA-mediated gene silencing in SGs (show FBN1 Antibodies).

  5. Maelstrom promotes hepatocellular carcinoma metastasis by inducing epithelial-mesenchymal transition by way of Akt (show AKT1 Antibodies)/GSK-3beta/Snail (show SNAI1 Antibodies) signaling.

  6. These results suggest that MAEL is a novel cancer/testis-associated gene and is regulated by DNA methylation (show HELLS Antibodies).

Mouse (Murine) Maelstrom Spermatogenic Transposon Silencer (MAEL) interaction partners

  1. MAEL HMG (show SSRP1 Antibodies)-box domain may contribute to MAEL function in selective processing of retrotransposon RNA into piRNAs.

  2. an important role for Mael in early oogenesis and during germ-cell differentiation from embryonic stem cells

  3. This study demonstrates that MAEL, a nuage component, is indispensable for the silencing of transposable elements (TEs (show TES Antibodies)) and identifies the initiation of meiosis as an important step in (TE) control in the male germline.

MAEL Antigen Profile

Protein Summary

Plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Its association with piP-bodies suggests a participation in the secondary piRNAs metabolic process. Required for localization of germ-cell factors to the meiotic nuage (By similarity).

Gene names and symbols associated with MAEL

  • maelstrom spermatogenic transposon silencer (MAEL) antibody
  • maelstrom spermatogenic transposon silencer (Mael) antibody
  • 4933405K18Rik antibody
  • AU019877 antibody
  • CT128 antibody
  • RGD1309333 antibody
  • RP11-102C16.1 antibody
  • SPATA35 antibody

Protein level used designations for MAEL

cancer/testis antigen 128 , maelstrom homolog , protein maelstrom homolog , spermatogenesis associated 35

GENE ID SPECIES
84944 Homo sapiens
98558 Mus musculus
364039 Rattus norvegicus
541073 Bos taurus
100048945 Sus scrofa
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