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Malate dehydrogenase catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. Additionally we are shipping Malate Dehydrogenase 1, NAD (Soluble) Antibodies (121) and Malate Dehydrogenase 1, NAD (Soluble) Proteins (24) and many more products for this protein.
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Data show that in the endogenous readthrough of the human MDH1 stop codon, the stop codon can encode tryptophan and arginine, and is tissue-specific.
Proliferating cells rely on both MDH1 and LDH to replenish cytosolic NAD.
Arginine methylation of MDH1 by CARM1 (show CARM1 ELISA Kits) regulates cellular redox homeostasis and suppresses glutamine (show GFPT1 ELISA Kits) metabolism of pancreatic cancer.
adipogenic differentiation may be regulated by the acetylation of MDH1
The MDH1 gene is not the cause of RP28-linked autosomal recessive retinitis pigmentosa.
expression of MDH1 is maintained in the adult heart but is not present in levels as high as in the fetus
Malate Dehydrogenase directly regulates the Tumor Suppressor Protein p53 (show TP53 ELISA Kits)-dependent apoptosis upon glucose deprivation and involved in maintaining cellular metabolic state and further determining cell death.
These findings provide strong evidence that MDH1 plays a critical role in osteoclast differentiation and function via modulation of the intracellular energy status, which might affect AMPK (show PRKAA1 ELISA Kits) activity and NFATc1 (show NFATC1 ELISA Kits) expression.
Mor2 is an essential factor for oocyte maturation and embryo development in mouse.
Structural features of the alphaB-crystallin (show CRYAB ELISA Kits) oligomer when complexed with target proteins under mild stress conditions, i.e., reduction of alpha-lactalbumin (show LALBA ELISA Kits) at 37 degrees C and malate dehydrogenase (show MDH ELISA Kits) when heated at 42 degrees C, were investigated.
Both immunofluorescence and immunoelectron microscopy demonstrated cMDH at the plasma membrane of LLC-PK(1) cells.
Observations on Mdh1 in both Gpdh (show GPD1 ELISA Kits) and Adh (show AVP ELISA Kits) backgrounds demonstrate significant increases in ethanol tolerance with partial reductions (50%) in cytosolic MDH (show MDH ELISA Kits) activity.
Malate dehydrogenase catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. The protein encoded by this gene is localized to the cytoplasm and may play pivotal roles in the malate-aspartate shuttle that operates in the metabolic coordination between cytosol and mitochondria. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
cytosolic malate dehydrogenase
, diiodophenylpyruvate reductase
, malate dehydrogenase, cytoplasmic
, soluble malate dehydrogenase
, malate dehydrogenase, soluble
, Malate dehydrogenase-like enzyme
, malate dehydrogenase 1, NAD (soluble)
, malate dehydrogenase 1Ab, cytoplasmic
, malate dehydrogenase 1Ab, peroxisomal
, malate dehydrogenase 1b, NAD (soluble)
, malate dehydrogenase, peroxisomal