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MDH1 Products

(Malate Dehydrogenase 1, NAD (Soluble) (MDH1))

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This gene encodes a mitochondrial NAD-dependent malic enzyme, a homotetrameric protein, that catalyzes the oxidative decarboxylation of malate to pyruvate. It had previously been weakly linked to a syndrome known as Friedreich ataxia that has since been shown to be the result of mutation in a completely different gene. Certain single-nucleotide polymorphism haplotypes of this gene have been shown to increase the risk for idiopathic generalized epilepsy. Alternatively spliced transcript variants encoding different isoforms found for this gene. [provided by RefSeq, Dec 2009].

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Featured MDH1 Categories

MDH1 Antibodies

High quality antibodies with extensive validation data.

MDH1 ELISA Kits

Reliable ELISA kits for a wide range of species.

MDH1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended MDH1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (5)
Cat. No. ABIN561768
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IP, IHC
Validations
  • (3)
Cat. No. ABIN7158940
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7158941
Quantity 100 μg
Datasheet Datasheet

Recommended MDH1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6968431
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6957626
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6957627
Quantity 96 tests
Datasheet Datasheet

Recommended MDH1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123834
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN5570480
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1310591
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our MDH1 products

Paul, Gangwar, Bhargava, Ahmad: "STAT3-RXR-Nrf2 activates systemic redox and energy homeostasis upon steep decline in pO2 gradient." in: Redox biology, Vol. 14, pp. 423-438, (2018) (PubMed).

Schmitz, Llorens, Pracht, Thom, Correia, Zafar, Ferrer, Zerr: "Regulation of human cerebrospinal fluid malate dehydrogenase 1 in sporadic Creutzfeldt-Jakob disease patients." in: Aging, Vol. 8, Issue 11, pp. 2927-2935, (2017) (PubMed).

Burr, Costa, Grice, Timms, Lobb, Freisinger, Dodd, Dougan, Lehner, Frezza, Nathan: "Mitochondrial Protein Lipoylation and the 2-Oxoglutarate Dehydrogenase Complex Controls HIF1α Stability in Aerobic Conditions." in: Cell metabolism, Vol. 24, Issue 5, pp. 740-752, (2016) (PubMed).

Nussbaumer, Asara, Teplytska, Murphy, Logan, Turck, Filiou: "Selective Mitochondrial Targeting Exerts Anxiolytic Effects In Vivo." in: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, Vol. 41, Issue 7, pp. 1751-8, (2016) (PubMed).

Stiebler, Freitag, Schink, Stehlik, Tillmann, Ast, Bölker: "Ribosomal readthrough at a short UGA stop codon context triggers dual localization of metabolic enzymes in Fungi and animals." in: PLoS genetics, Vol. 10, Issue 10, pp. e1004685, (2014) (PubMed).

Povlsen, Løfgren, Dalgas, Birkler, Johannsen, Støttrup, Bøtker: "Protection against myocardial ischemia-reperfusion injury at onset of type 2 diabetes in Zucker diabetic fatty rats is associated with altered glucose oxidation." in: PLoS ONE, Vol. 8, Issue 5, pp. e64093, (2013) (PubMed).

Ota, Suzuki, Nishikawa, Otsuki, Sugiyama, Irie, Wakamatsu, Hayashi, Sato, Nagai, Kimura, Makita, Sekine, Obayashi, Nishi, Shibahara, Tanaka, Ishii, Yamamoto, Saito, Kawai, Isono, Nakamura, Nagahari et al.: "Complete sequencing and characterization of 21,243 full-length human cDNAs. ..." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, (2003) (PubMed).

Tanaka, Inazawa, Nakamura: "Molecular cloning and mapping of a human cDNA for cytosolic malate dehydrogenase (MDH1)." in: Genomics, Vol. 32, Issue 1, pp. 128-30, (1996) (PubMed).

Synonyms and alternative names related to MDH1

malate dehydrogenase 1 (MDH1), malic enzyme 2 (ME2), malate dehydrogenase 1, NAD (soluble) (Mdh1), malate dehydrogenase 1 (Mdh1), malate dehydrogenase 1 S homeolog (mdh1.S), malate dehydrogenase, cytoplasmic (LOC100280767), Malate dehydrogenase 1 (Mdh1), B230377B03Rik, cMdh, D17921, MDH, Mdh, MDH-1, Mdh-1, MDH-s, mdh-s, Mdh2, MDHA, mdha, MdhD, Mdhl, MDL1, MGC:1375, Mor-2, MOR2, Mor2, mor2, ODS1, sMdh

Protein level used designations for MDH1

  • cytosolic malate dehydrogenase
  • diiodophenylpyruvate reductase
  • malate dehydrogenase, cytoplasmic
  • soluble malate dehydrogenase
  • NAD-ME
  • NAD-dependent malic enzyme, mitochondrial
  • malate dehydrogenase
  • pyruvic-malic carboxylase
  • malate dehydrogenase, soluble
  • Malate dehydrogenase-like enzyme
  • malate dehydrogenase 1, NAD (soluble)
  • malate dehydrogenase, peroxisomal
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