anti-Malic Enzyme Complex, Mitochondrial (Mod2) Antibodies

The membrane-associated protein encoded by Mod2 is a member of the superfamily of ATP-binding cassette (ABC) transporters. Additionally we are shipping and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
Anti-Mouse Mod2 Mod2 110357  
Mod2 5243 P08183
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Top anti-Malic Enzyme Complex, Mitochondrial Antibodies at

Showing 4 out of 4 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Human Mouse Magnetic Particles IP   100 μg 4 to 6 Days
Human Mouse Sepharose IP   100 μg 4 to 6 Days
Human Mouse Un-conjugated ICC, IHC (fro), IHC (p), WB   100 μg 4 to 6 Days
Human Mouse Un-conjugated IHC   100 μL 12 to 14 Days

More Antibodies against Malic Enzyme Complex, Mitochondrial Interaction Partners

Human Malic Enzyme Complex, Mitochondrial (Mod2) interaction partners

  1. In both extravillous trophoblast and cytotrophoblast explant differentiation experiments, silencing of ABCB1 leads to induction of the fusion markers human hCG, ERVW-1 and GJA1 and terminal differentiation of both trophoblast subtypes.

  2. Together with previous data, these findings lead to a general model of substrate and inhibitor coupling to P-glycoprotein.

  3. We performed the first population PK-PD study assessing the influence of ABCB1 gene polymorphisms and the expression of this gene on the thromboprophylactic therapy with rivaroxaban in patients undergoing knee or hip replacement surgery. We observed a decrease in ABCB1 expression after the orthopedic surgery and demonstrated a positive correlation between the ABCB1 gene expression and the rivaroxaban CL/F.

  4. The donor and recipient CYP3A5*3 polymorphism influences tacrolimus pharmacokinetics in the first month post-transplantation, whereas the association with recipient ABCB1 3435 C > T is inconclusive.

  5. high expression of MDR1 can affect the efflux ability to Methotrexate (MTX) by up-regulating the expression of P-gp, thus enhancing the drug resistance to MTX in rheumatoid arthritis fibroblast-like synoviocytes

  6. Genotypes of the rs1202184 locus of the MDR1 gene are associated with refractory epilepsy in children, for which the AA genotype plays a dominant role.

  7. Results indicate that elevated ABCB1 expression induced by C-terminal truncation of HBx was responsible for doxorubicin resistance in HCC.

  8. The results reveal the potential regulatory mechanism of FTH1P3 on breast cancer paclitaxel resistance through miR-206/ABCB1 axis.

  9. Crown ethers reverse P-glycoprotein-mediated multidrug resistance in cancer cells.

  10. High MDR1 expression is associated with acute lymphoblastic leukemia.

  11. The study demonstrated that the simultaneous presence of TMDR1, A CYP2D6*4 and A NAT2*7 alleles robustly increased the risk of developing ulcerative colitis by 3.49-fold. The current study suggests that CYP2D6*4 and MDR1 3435 C/T gene polymorphisms may be risk factors for UC susceptibility.

  12. HIF1A-induced MDR1 and MRP4 promote Th17 responses in Crohn's disease.

  13. In conclusion, we provide evidence that P-gp may be involved in an AhR-dependent detoxification process induced in response to the uremic toxin IS.

  14. sofosbuvir GS-331007 metabolite plasma levels were affected by variants in the ABCB1 and HNFalpha genes

  15. The contribution of polymorphisms in ABCB1 to drug pharmacokinetics.

  16. FENDRR attenuates NSCLC cell stemness through inhibiting the HuR/MDR1 axis

  17. Significant associations between SNPs in MDR1 and outcome of multiple myeloma (MM) were found in 110 MM patients that underwent bortezomib-based treatment.

  18. WBP2 directly promoted P-glycoprotein expression through binding to ERalpha to increase the doxorubicin resistance of ERalpha-positive MCF-7 cells.

  19. this study shows that high MDR-1 expression by mucosal-associated invariant T cells confers resistance to cytotoxic but not immunosuppressive MDR-1 substrates

  20. A correlation exists between the ABCB1 C3435T gene polymorphism and post-stroke depression in the Han population in South Anhui province, China.

Malic Enzyme Complex, Mitochondrial (Mod2) Antigen Profile

Protein Summary

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier.

Gene names and symbols associated with Mod2

  • malic enzyme complex, mitochondrial (Mod2) antibody
  • ATP binding cassette subfamily B member 1 (ABCB1) antibody
  • ABC20 antibody
  • CD243 antibody
  • CLCS antibody
  • GP170 antibody
  • Mdr antibody
  • Mdr-1 antibody
  • MDR1 antibody
  • Mod-2 antibody
  • Mod-2r antibody
  • Mod-2s antibody
  • Mod2-r antibody
  • Mod2-s antibody
  • P-GP antibody
  • PGY1 antibody

Protein level used designations for Mod2

malic enzyme complex, mitochondrial , malic enzyme, mitochondrial regulatory , malic enzyme, mitochondrial structural , P-glycoprotein 1 , colchicin sensitivity , doxorubicin resistance , multidrug resistance protein 1

110357 Mus musculus
5243 Homo sapiens
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