Maternal Embryonic Leucine Zipper Kinase (MELK) ELISA Kits

Serine/threonine-protein kinase involved in various processes such as cell cycle regulation, self-renewal of stem cells, apoptosis and splicing regulation (By similarity). Additionally we are shipping MELK Antibodies (152) and MELK Proteins (14) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
MELK 9833 Q14680
MELK 17279 Q61846
MELK 362510  
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Top MELK ELISA Kits at antibodies-online.com

Showing 7 out of 25 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.039 ng/mL 0.156-10 ng/mL Typical standard curve 96 Tests Log in to see 15 to 18 Days
$910.56
Details
Mouse 0.057 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests Log in to see 13 to 16 Days
$757.89
Details
Rat 0.063 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests Log in to see 13 to 16 Days
$800.00
Details
Human
  96 Tests Log in to see 2 to 3 Days
$380.00
Details
Human < 0.121 ng/mL 0.312 ng/mL - 20 ng/mL   96 Tests Log in to see 11 to 18 Days
$810.17
Details
Mouse < 0.057 ng/mL 0.156 ng/mL - 10 ng/mL   96 Tests Log in to see 11 to 18 Days
$824.38
Details
Rat < 0.063 ng/mL 0.156 ng/mL - 10 ng/mL   96 Tests Log in to see 11 to 18 Days
$867.02
Details

More ELISA Kits for MELK Interaction Partners

Human Maternal Embryonic Leucine Zipper Kinase (MELK) interaction partners

  1. Study demonstrates that the interaction occurring between MELK and EZH2 (show EZH2 ELISA Kits) promotes self-proliferation and stemness.

  2. In common culture conditions, the authors found that small molecule inhibition, genetic deletion, or acute depletion of MELK did not significantly affect cellular growth.

  3. Synthesis of MCL1 (show MCL1 ELISA Kits), an antiapoptotic protein known to play a role in cancer cell survival during cell division, depends on the function of MELK-elF4B signaling.

  4. Inhibition of MELK (genetically and pharmacologically) induces radiation sensitivity.

  5. MELK is a host factor required for optimal uncoating of the HIV-1 core to promote viral cDNA synthesis.

  6. Here, the authors report that mutagenizing MELK with CRISPR/Cas9 has no effect on the fitness of basal breast cancer cell lines or cell lines from six other cancer types. Cells that harbor null mutations in MELK exhibit wild-type doubling times, cytokinesis, and anchorage-independent growth.

  7. MELK-inhibitor has a role in triple-negative breast cancer cells demonstrating context-dependent response with p53 (show TP53 ELISA Kits) as a key determinant

  8. MELK is an oncogenic kinase involved in the pathogenesis and recurrence of hepatocellular carcinoma.

  9. Inhibition or depletion of MELK reduced cell proliferation and anchorage-dependent and -independent growth in various ovarian cancer cell lines through a G2/M cell cycle arrest, eventually resulting in apoptosis.

  10. Report IL11RA (show IL11RA ELISA Kits) and MELK amplification in gastric cancer cell lines and primary gastric adenocarcinomas.

Mouse (Murine) Maternal Embryonic Leucine Zipper Kinase (MELK) interaction partners

  1. MELK promotes cell migration and invasion via the FAK (show PTK2 ELISA Kits)/Paxillin (show PXN ELISA Kits) pathway, and plays an important role in the occurrence and development of gastric cancer.

  2. Phosphorylation of the activation loop of MPK38 induces its movement resulting in kinase activation.

  3. These results indicate that Trx (show TXN ELISA Kits) functions as a physiological inhibitor of MPK38, which plays an important role in inducing ASK1 (show MAP3K5 ELISA Kits)-, TGF-beta (show TGFB1 ELISA Kits), and p53 (show TP53 ELISA Kits)-mediated activity

  4. an important role for MPK38-mediated phosphorylation of PDK1 (show PDPK1 ELISA Kits) in the negative regulation of PDK1 (show PDPK1 ELISA Kits) activity.

  5. MPK38 may act as a novel regulator for promoting p53 (show TP53 ELISA Kits) activity through direct phosphorylation of p53 (show TP53 ELISA Kits) at Ser (show SIGLEC1 ELISA Kits)(15).

  6. Upregulation of maternal embryonic leucine zipper kinase is associated with mammary tumor.

  7. MELK is necessary for proliferation of embryonic and postnatal MNP and suggest that it regulates the transition from GFAP (show GFAP ELISA Kits)-expressing progenitors to rapid amplifying progenitors in the postnatal brain.

  8. The characterization of two novel E2F (show E2F1 ELISA Kits) target genes, chromosome condensation-related SMC-associated protein 1 (Cnap1) and maternal embryonic leucine zipper kinase (Melk) is reported.

  9. MPK38 physically interacts with ASK1 (show MAP3K5 ELISA Kits) in vivo and acts as a positive upstream regulator of ASK1 (show MAP3K5 ELISA Kits)

Zebrafish Maternal Embryonic Leucine Zipper Kinase (MELK) interaction partners

  1. Melk-like gene may play a role in primitive hematopoiesis by affecting the expression of genes critical for hematopoiesis.

Xenopus laevis Maternal Embryonic Leucine Zipper Kinase (MELK) interaction partners

  1. Overexpression of xMELK leads to failure of cytokinesis and impairs accumulation RhoA- a pivotal regulator of cytokinesis.

  2. These results demonstrate the presence of a mitochondrial targeting signal at the N-terminus of the MC domain of MELK. This mitochondrial targeting signal was also functional in human HeLa cells.[MELK]

MELK Antigen Profile

Antigen Summary

Serine/threonine-protein kinase involved in various processes such as cell cycle regulation, self-renewal of stem cells, apoptosis and splicing regulation (By similarity). Also plays a role in primitive hematopoiesis, possibly by affecting the expression of genes critical for hematopoiesis.

Gene names and symbols associated with MELK

  • maternal embryonic leucine zipper kinase (MELK) antibody
  • maternal embryonic leucine zipper kinase (melk) antibody
  • maternal embryonic leucine zipper kinase (cgd5_2270) antibody
  • maternal embryonic leucine zipper kinase (Melk) antibody
  • maternal embryonic leucine zipper kinase L homeolog (melk.L) antibody
  • AI327312 antibody
  • fb71b01 antibody
  • fe01f04 antibody
  • HPK38 antibody
  • Melk antibody
  • mKIAA0175 antibody
  • MPK38 antibody
  • wu:fb71b01 antibody
  • wu:fe01f04 antibody
  • xmelk antibody

Protein level used designations for MELK

maternal embryonic leucine zipper kinase , maternal embryonic leucine zipper kinase-like , pEg3 kinase , protein kinase Eg3 , protein kinase PK38 , tyrosine-protein kinase MELK , zMelk , Protein kinase Eg3

GENE ID SPECIES
428391 Gallus gallus
465095 Pan troglodytes
549144 Xenopus (Silurana) tropicalis
3373320 Cryptosporidium parvum Iowa II
100123808 Nasonia vitripennis
100386947 Callithrix jacchus
100586707 Nomascus leucogenys
9833 Homo sapiens
481608 Canis lupus familiaris
520088 Bos taurus
17279 Mus musculus
362510 Rattus norvegicus
30724 Danio rerio
397927 Xenopus laevis
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