MELK Products
(Maternal Embryonic Leucine Zipper Kinase (MELK))
Categories
Serine/threonine-protein kinase involved in various processes such as cell cycle regulation, self-renewal of stem cells, apoptosis and splicing regulation (By similarity). Also plays a role in primitive hematopoiesis, possibly by affecting the expression of genes critical for hematopoiesis.
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Featured MELK Categories
MELK Antibodies
High quality antibodies with extensive validation data.
MELK ELISA Kits
Reliable ELISA kits for a wide range of species.
MELK Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended MELK Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, IHC, ICC, FACS
Validations
- (2)
- (5)
Cat. No.
ABIN969538
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IF, IHC, FACS
Validations
- (5)
Cat. No.
ABIN1491623
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC, FACS, IF/ICC
Validations
- (6)
Cat. No.
ABIN1844288
Quantity
100 μL
Datasheet
Datasheet
Recommended MELK ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6968452
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6957654
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6957655
Quantity
96 tests
Datasheet
Datasheet
Recommended MELK Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (2)
Cat. No.
ABIN5569684
Quantity
5 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect cells (Sf9)
Validations
- (2)
Cat. No.
ABIN5569614
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1310711
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our MELK products
: "Phillygenin, a MELK Inhibitor, Inhibits Cell Survival and Epithelial-Mesenchymal Transition in Pancreatic Cancer Cells." in: OncoTargets and therapy, Vol. 13, pp. 2833-2842, (2020) (PubMed).: "Tumor-specific chromosome mis-segregation controls cancer plasticity by maintaining tumor heterogeneity." in: PLoS ONE, Vol. 8, Issue 11, pp. e80898, (2013) (PubMed).
: "Siomycin A targets brain tumor stem cells partially through a MELK-mediated pathway." in: Neuro-oncology, Vol. 13, Issue 6, pp. 622-34, (2011) (PubMed).
: "Dysregulated expression of Fau and MELK is associated with poor prognosis in breast cancer." in: Breast cancer research : BCR, Vol. 11, Issue 4, pp. R60, (2009) (PubMed).
: "Involvement of maternal embryonic leucine zipper kinase (MELK) in mammary carcinogenesis through interaction with Bcl-G, a pro-apoptotic member of the Bcl-2 family." in: Breast cancer research : BCR, Vol. 9, Issue 1, pp. R17, (2007) (PubMed).
: "The changing AMPK expression profile in differentiating mouse skeletal muscle myoblast cells helps confer increasing resistance to apoptosis." in: Experimental physiology, Vol. 92, Issue 1, pp. 207-17, (2007) (PubMed).
: "Human pEg3 kinase associates with and phosphorylates CDC25B phosphatase: a potential role for pEg3 in cell cycle regulation." in: Oncogene, Vol. 21, Issue 50, pp. 7630-41, (2002) (PubMed).
: "Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1." in: DNA research : an international journal for rapid publication of reports on genes and genomes, Vol. 3, Issue 1, pp. 17-24, (1996) (PubMed).
Synonyms and alternative names related to MELK
maternal embryonic leucine zipper kinase (MELK), maternal embryonic leucine zipper kinase (melk), maternal embryonic leucine zipper kinase (cgd5_2270), maternal embryonic leucine zipper kinase (Melk), maternal embryonic leucine zipper kinase L homeolog (melk.L), AI327312, fb71b01, fe01f04, HPK38, MELK, Melk, mKIAA0175, MPK38, wu:fb71b01, wu:fe01f04, xmelkProtein level used designations for MELK
- maternal embryonic leucine zipper kinase
- maternal embryonic leucine zipper kinase-like
- pEg3 kinase
- protein kinase Eg3
- protein kinase PK38
- tyrosine-protein kinase MELK
- zMelk
- Protein kinase Eg3
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