Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) ELISA Kits

Human Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) interaction partners

1. study to explore the relationship between 2 polymorphisms (MMP-1-755 T/G [rs498186] and MMP-3 (show MMP3 ELISA Kits) A/C [rs632478]) and disc degeneration; no significant association of the MMP-1 polymorphism with disc degeneration was found

2. Expression of GSDMC is increased by UV irradiation in human skin keratinocytes. GSDMC induction contributes to the increase of MMP-1 expression specifically via activation of ERK (show EPHB2 ELISA Kits) and JNK (show MAPK8 ELISA Kits) pathways.

3. our results suggest that the typical 1G/2G MMP-1 polymorphic site did not play a direct determinant role in breast cancer among Taiwanese women.

4. The maternal and fetal 1G/1G MMP1 gene polymorphisms may be strong genetic markers of preeclampsia, occurring either individually or together.

5. The current study indicated that MMP1 has a key role in the regulation of cervical tumor growth and lymph node metastasis via epithelial mesenchymal transition to a certain extent

6. 2G allele of MMP-1, C allele of MMP-2 (show MMP2 ELISA Kits) and 5A/6A genotype of MMP-3 (show MMP3 ELISA Kits) are associated with susceptibility and disease progression of type 2 diabetic nephropathy

7. this study provides insights into the development of a possible alternative therapy manipulating MMP-1 and the mTOR (show FRAP1 ELISA Kits) signaling pathway in Epidermal growth factor receptor (show EGFR ELISA Kits)-tyrosine kinase (show RET ELISA Kits) inhibitor-resistant lung adenocarcinoma.

8. Specific silencing that targeted AMPK (show PRKAA1 ELISA Kits) resulted in the enhancement of mobility and contractility and in the production of MMP-1 and MMP-2 (show MMP2 ELISA Kits).

9. MMP-1 genotype may accelerate the development of HIV-associated neurocognitive disorder (HAND) whereas MMP3 (show MMP3 ELISA Kits) -1612 5A5A genotype may reduce the risk of pathogenesis of HAND.

10. Authors observed a significant increase in the immunoexpression of collagen I and III in patients with DCM and a significant reduction in the immunoexpression of MMP-1 compared with the control group. Also, the collagen I and TIMP-1 (show TIMP1 ELISA Kits) expression indicated a positive linear correlation and respectively a negative linear relationship with collagen III and MMP-1.

Pig (Porcine) Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) interaction partners

1. the identification of MMP1 and MMP10 (show MMP10 ELISA Kits) genes in swine is reported.

2. increased interstitial MMP1 activity during ischemia and reperfusion is a result of the endothelin protein kinase c (show PKC ELISA Kits) pathway and may be due to enhanced phosphorylation of mmp1

3. Results indicate that leukemia inhibitory factor (LIF (show LIF ELISA Kits)) and Oncostatin M (show OSM ELISA Kits) increase the expression of MMP-1, MMP-3 (show MMP3 ELISA Kits), and TIMP-1 (show TIMP1 ELISA Kits) several fold, and that their expression is reduced to basal levels in the presence of the LIF (show LIF ELISA Kits) antagonist MH35-BD.

Fruit Fly (Drosophila melanogaster) Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) interaction partners

1. results suggest that Ubx regulates organ shape by controlling Mmp1 expression, and the extent and timing of extracellular matrix degradation.

2. This work identifies Draper-dependent activation of MMP-1 as a novel cascade required for proper glial clearance of severed axons.

3. Mmp1 negatively regulates ectopic eye differentiation by restricting the rate of proliferation and the levels of expression of retinal-determining genes dachshund and eyes absent.

4. Data indicate that matrix metalloproteinases mmp1 and mmp2 (show MMP2 ELISA Kits) mutants have distinct heart phenotypes.

5. These data demonstrate that Mmp1 modulates PDF processing, which leads to daily structural remodeling and circadian behavior.

6. A primary function of Mmp1, under the control of the JNK (show MAPK8 ELISA Kits) pathway, is to promote basement membrane repair, which in turn may permit cell migration and the restoration of a continuous tissue.

7. Drosophila Mmp1 is involved in the regulation of ISC proliferation for maintenance of gut (show GUSB ELISA Kits) homeostasis

8. Study identified three genes, regeneration (rgn (show RGN ELISA Kits)), augmenter of liver regeneration (alr (show GFER ELISA Kits)) and Matrix metalloproteinase-1 (Mmp1) expressed specifically in blastema cells during disc regeneration.

Mouse (Murine) Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) interaction partners

1. Infection with Mycobacterium bovis results in increase in interleukin-1alpha, TGF-beta1 (show TGFB1 ELISA Kits), and MMP1 in multinucleated macrophages.

2. MMP-2 (show MMP2 ELISA Kits) promoted and MMP-13 (show MMP13 ELISA Kits) disrupted vasculogenic mimicry formation in large cell lung cancer by cleaving laminin-5 to influence EGFR (show EGFR ELISA Kits) signal activation.

3. The data demonstrate that MMP13 (show MMP13 ELISA Kits) and CTGF (show CTGF ELISA Kits) play a crucial role in modulation of fibrogenic mediators while promoting hepatic fibrogenesis.

4. CXCL10 (show CXCL10 ELISA Kits) has strong inhibitory effects on neovascularization, whereas MMP13 (show MMP13 ELISA Kits) is required for neovascularization in C. albicans-infected corneas.

5. that MMP-13 (show MMP13 ELISA Kits) is a central protease in infarct development and cortical remodeling during post-stroke neurorepair

6. the phenotype seen in the Hdac4 (show HDAC5 ELISA Kits)(-/-) mice is partially derived from elevation in MMP-13 (show MMP13 ELISA Kits) and may be due to a bone remodeling disorder caused by overexpression of this enzyme.

7. MEF2C (show MEF2C ELISA Kits) is necessary for Mmp13 (show MMP13 ELISA Kits) gene expression at the transcriptional level and participates in PTH (show PTH ELISA Kits)-stimulated Mmp13 (show MMP13 ELISA Kits) gene expression by increased binding to c-FOS at the AP-1 (show JUN ELISA Kits) site in the Mmp13 (show MMP13 ELISA Kits) promoter.

8. data reveal a novel involvement of MMP-13 (show MMP13 ELISA Kits) in regulating dendritic cell (DC) immunobiology through moderating MHC-I surface presentation, endocytosis and cytokine/chemokine (show CCL1 ELISA Kits) secretion; furthermore, the reduced MHC-I surface presentation by DCs resulted in a poor CD8 (show CD8A ELISA Kits)(+) T-cell response in vitro; MMP-13 (show MMP13 ELISA Kits) might be a promising target for therapeutic intervention in inflammatory diseases

9. The progressive process of articular cartilage degeneration was significantly delayed in the knee joints of Ddr2 (show DDR2 ELISA Kits)-deficient mice in comparison to their control littermates. Articular cartilage damage in the knee joints of the mice was associated with increased expression profiles of both Ddr2 (show DDR2 ELISA Kits) and matrix metalloproteinase 13 (show MMP13 ELISA Kits).

10. Postnatal chondrocyte-specific deletion of Hdac3 (show HDAC3 ELISA Kits) with an inducible Col2a1 (show COL2A1 ELISA Kits)-Cre caused premature production of pErk1/2 and Mmp13 (show MMP13 ELISA Kits) in the growth plate.

Cow (Bovine) Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) interaction partners

1. BoHV-4 infection affects various pathways related to cell proliferation and cell surface integrity, at least three of which were centered on upregulation of matrix metalloproteinase 1 (MMP1). MMP1 transcription was upregulated by the BoHV-4 transactivator IE2/RTA (show RBM9 ELISA Kits), leading to abnormally high metalloproteinase tissue levels, potentially leading to defective endometrium healing and unresolved inflammation.

2. The expression patterns of MMP1, MMP2 (show MMP2 ELISA Kits), and MMP8 (show MMP8 ELISA Kits) were explored during fetal and postnatal development of longissimus dorsi muscle in cattle, and the relationships of MMP1, MMP2 (show MMP2 ELISA Kits), and MMP8 (show MMP8 ELISA Kits) expression levels with meat quality traits were analyzed in cattle. The expression of MMP1, MMP2 (show MMP2 ELISA Kits), and MMP8 (show MMP8 ELISA Kits) were also tested in four kinds of fat tissues and three kinds of skeletal muscle tissues.

3. Data suggest that luteolytic factors (such as interferon gamma (show IFNG ELISA Kits), tumor necrosis factor alpha (show TNF ELISA Kits), and PGF2a) control expression of MMP1, other matrix metalloproteinases, and tissue inhibitors of metalloproteinase in cultured luteal cells.

4. The results showed that a decrease in MMP-1 and MMP-2 (show MMP2 ELISA Kits) gene expression is accompanied with a decrease in NO concentrations in infertile cows affected with ovarian cysts.

5. Cytoskeletal tension modulates MMP-1 gene expression from tenocytes on micropillar substrates.

6. MMP-1 promotes VEGFR2 (show KDR ELISA Kits) expression and proliferation of endothelial cells through stimulation of PAR-1 (show F2R ELISA Kits) and activation of NF-kappaB (show NFKB1 ELISA Kits)

7. These data identify atypical PKC isozymes as STAT and ERK activators that mediate c-fos and collagenase expression.

8. the differential expression and localization of membrane-type 1 matrix metalloproteinase (show MMP14 ELISA Kits) in the corpus luteum suggest that it may have multiple functions throughout the course of the estrous cycle,including activation of pro-MMP-2 (show MMP2 ELISA Kits)

9. increased in bovine preovulatory follicles following the gonadotropin surge but no up-regulation of MMP-1 and MMP-13 (show MMP13 ELISA Kits) (follicular apex (show APEX1 ELISA Kits) vs. base) for the preovulatory collagenolysis required for follicle rupture

10. identification of MT1-MMP (show MMP14 ELISA Kits) in odontoclasts during deciduous tooth resorption might be relevant to the migration activity that these cells have to gain access to the root surface

Rabbit Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) interaction partners

1. These results suggest that PEP-1-SIRT2 (show SIRT2 ELISA Kits) promotes matrix metalloproteinases-induced dedifferentiation via ERK (show MAPK1 ELISA Kits) signaling in articular chondrocytes. .

2. Circulating smoke components, including acrolein, contribute to vascular diseases through enhanced MMP-1 and decreased TIMP-3 (show TIMP3 ELISA Kits) secretion.

Horse (Equine) Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) interaction partners

1. ANXA2 (show ANXA2 ELISA Kits) and MMP1 might participate in remodeling during wound healing in the horse.

2. The polymorphism in the promoter of the MMP-1 gene could be a risk factor for early implant failure of total hip arthroplasty.

3. These results suggest that MMP-1 and IL-8 (show IL8 ELISA Kits) are both involved in the exercise-induced stress response, and this represents a starting point from which to understand the adaptive responses to this phenomenon.

Xenopus laevis Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) interaction partners