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Required for normal meiotic chromosome synapsis. Additionally we are shipping Meiosis Inhibitor 1 Proteins (3) and many more products for this protein.
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Mei1 is required for vertebrate meiosis.
Mei1 can be positioned upstream of Dmc1 in the genetic pathway that operates during mammalian meiosis.
we report on a homozygous missense mutation in the gene coding for meiotic double-stranded break formation protein 1 observed in two brothers with non-obstructive azoospermia and meiotic arrest. A fertile brother was heterozygous for the mutation. All the queried databases predicted that this mutation is damaging, and it has previously been reported that Mei1 knock-out is associated with meiotic arrest in a murine model.
MEI1 may play a role in meiosis during spermatogenesis, especially in European Americans.
data suggest that bMei1 may play an important role in the meiosis of spermatogenesis and may be involved in cattle-yak male sterility, and its transcription was regulated by DNA methylation
Required for normal meiotic chromosome synapsis. May be involved in the formation of meiotic double-strand breaks (DSBs) in spermatocytes (By similarity).
meiosis inhibitor 1
, meiosis defective 1
, meiosis defective protein 1
, meiosis inhibitor protein 1
, spermatogenesis associated 38