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Receptor for melanin-concentrating hormone, coupled to G proteins that activate phosphoinositide hydrolysis.. Additionally we are shipping MCHR2 Kits (4) and and many more products for this protein.
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evidence for the involvement of duplications in MCHR2 in alopecia areata pathogenesis in a Central European cohort
This study provides new insights on the possible influence of MCHR2 and/or MCHR2-AS1 on obesity in psychiatric patients and on the pathophysiology of atypical depression.
Discovery and characterization of a potent and selective antagonist of melanin-concentrating hormone receptor 2
construction of the CHO cell line and the research of MCHR2 molecular characteristics have established a good experimental basis for the further research about the function of MCHR2 gene
MCH1 and MCH2 receptors were investigated and are different from those in SVK14 cells.
results of molecular simulations of MCHR2 in the free and hormone-bound forms provide suggestions on the amino acids responsible for the transfer of the structural changes from the agonist binding site to the G-protein coupling domains
MCHR2 is not a major contributor to polygenic obesity
MCHR2 positively mediates the regulation of melanin-concentrating hormone during preadipocyte differentiation and is involved in energy balance regulation without affecting preadipocyte proliferation.
The 10-amino-acid cyclic core of the hMCH neuropeptide with the Arg attached to the N-terminus of the disulfide ring is sufficient for full activation of melanin-concentrating hormone receptor 2.
Receptor for melanin-concentrating hormone, coupled to G proteins that activate phosphoinositide hydrolysis.
G protein-coupled receptor 145
, G protein-coupled receptor slt
, G-protein coupled receptor 145
, MCH receptor 2
, melanin-concentrating hormone 2
, melanin-concentrating hormone receptor subtype 2