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MDC1 Antibodies

(Mdc1 (MDC1))
The protein encoded by this gene contains an N-terminal forkhead domain, two BRCA1 C-terminal (BRCT) motifs and a central domain with 13 repetitions of an approximately 41-amino acid sequence. The encoded protein is required to activate the intra-S phase and G2/M phase cell cycle checkpoints in response to DNA damage. This nuclear protein interacts with phosphorylated histone H2AX near sites of DNA double-strand breaks through its BRCT motifs, and facilitates recruitment of the ATM kinase and meiotic recombination 11 protein complex to DNA damage foci. [provided by RefSeq, Jul 2008].
MDC1 antibody  (Center) MDC1 antibody  (Center) MDC1 antibody (Center) (ABIN2855454)

MDC1 Reactivity: Human IHC (p), WB Host: Rabbit Polyclonal unconjugated

MDC1 antibody  (N-Term) MDC1 antibody  (N-Term) MDC1 antibody (N-Term) (ABIN863114)

MDC1 Reactivity: Mouse ICC, IF, WB Host: Mouse Monoclonal P2B11 unconjugated

MDC1 antibody  (N-Term) (HRP) MDC1 antibody  (N-Term) (HRP) MDC1 antibody (N-Term) (HRP) (ABIN2484153)

MDC1 Reactivity: Mouse ICC, IF, WB Host: Mouse Monoclonal P2B11 HRP

MDC1 Antibodies by Reactivity

Find MDC1 Antibodies for a variety of species such as anti-Human MDC1, anti-Mouse MDC1, anti-Rat MDC1. The species listed below are among those available. Click on a link to go to the corresponding products.

MDC1 Antibodies by Application

Find MDC1 Antibodies validated for a specific application such as WB, IF, ICC, IF (cc). Some of the available applications are listed below. Click on a link to go to the corresponding products.

MDC1 Antibodies by Host

Find MDC1 Antibodies with a specific Host. The Host listed below are among those available. Click on a link to go to the corresponding products.

MDC1 Antibodies by Binding Specificity

Find MDC1 Antibodies with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

MDC1 Antibodies by Clonality

Find available monoclonal or polyclonal MDC1 Antibodies. Click on a link to go to the corresponding products.

MDC1 Antibodies by Clone

Find MDC1 Antibodies with a specific Clone. The Clone listed below are among those available. Click on a link to go to the corresponding products.

MDC1 Antibodies by Conjugate

Find MDC1 Antibodies with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular MDC1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Application ICC, IF, WB
Validations
  • (3)
Cat. No. ABIN2484152
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Application ICC, IF, WB
Validations
  • (3)
Cat. No. ABIN2484149
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Application ICC, IF, WB
Validations
  • (3)
Cat. No. ABIN2484151
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Application ICC, IF, WB
Validations
  • (3)
Cat. No. ABIN2484156
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Application ICC, IF, WB
Validations
  • (3)
Cat. No. ABIN2484150
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Application ICC, IF, WB
Validations
  • (3)
Cat. No. ABIN2484155
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Application ICC, IF, WB
Validations
  • (3)
Cat. No. ABIN2484142
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Application ICC, IF, WB
Validations
  • (3)
Cat. No. ABIN2484144
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Application ICC, IF, WB
Validations
  • (3)
Cat. No. ABIN2484141
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (3)
Cat. No. ABIN5693232
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, IF (cc), IF (p), IHC (fro), IHC (p), WB
Validations
  • (3)
Cat. No. ABIN739740
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IF, IHC
Validations
  • (2)
Cat. No. ABIN7159096
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application IHC, IHC (p), WB
Validations
  • (2)
Cat. No. ABIN1499348
Quantity 100 μL
Datasheet Datasheet
Reactivity Dog, Human, Pig
Application IHC, IHC (p), WB
Validations
  • (2)
Cat. No. ABIN6754878
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (1)
Cat. No. ABIN7138640
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our MDC1 Antibodies

Huo, Chen, Cheng, Song, Zhang, Li, Xuan: "JMJD6 modulates DNA damage response through downregulating H4K16ac independently of its enzymatic activity." in: Cell death and differentiation, (2019) (PubMed).

Burger, Schlackow, Gullerova: "Tyrosine kinase c-Abl couples RNA polymerase II transcription to DNA double-strand breaks." in: Nucleic acids research, Vol. 47, Issue 7, pp. 3467-3484, (2019) (PubMed).

Chen, Tsai, Wang, Teng: "SMYD3 Promotes Homologous Recombination via Regulation of H3K4-mediated Gene Expression." in: Scientific reports, Vol. 7, Issue 1, pp. 3842, (2017) (PubMed).

Hodge, Ismail, Edwards, Hura, Xiao, Tainer, Hendzel, Glover: "RNF8 E3 Ubiquitin Ligase Stimulates Ubc13 E2 Conjugating Activity That Is Essential for DNA Double Strand Break Signaling and BRCA1 Tumor Suppressor Recruitment." in: The Journal of biological chemistry, Vol. 291, Issue 18, pp. 9396-410, (2016) (PubMed).

Bick, Zhang, Meetei, Andreassen: "Coordination of the recruitment of the FANCD2 and PALB2 Fanconi anemia proteins by an ubiquitin signaling network." in: Chromosoma, (2016) (PubMed).

Saquilabon Cruz, Kong, Silva, Khatibzadeh, Thai, Berns, Yokomori: "Femtosecond near-infrared laser microirradiation reveals a crucial role for PARP signaling on factor assemblies at DNA damage sites." in: Nucleic acids research, Vol. 44, Issue 3, pp. e27, (2016) (PubMed).

Ge, Che, Du: "The UBC Domain Is Required for BRUCE to Promote BRIT1/MCPH1 Function in DSB Signaling and Repair Post Formation of BRUCE-USP8-BRIT1 Complex." in: PLoS ONE, Vol. 10, Issue 12, pp. e0144957, (2015) (PubMed).

Münch, Weidtkamp-Peters, Klement, Grigaravicius, Monajembashi, Salomoni, Pandolfi, Weißhart, Hemmerich: "The tumor suppressor PML specifically accumulates at RPA/Rad51-containing DNA damage repair foci but is nonessential for DNA damage-induced fibroblast senescence." in: Molecular and cellular biology, Vol. 34, Issue 10, pp. 1733-46, (2014) (PubMed).

Silva, Stambaugh, Yokomori, Shah, Berns: "DNA damage to a single chromosome end delays anaphase onset." in: The Journal of biological chemistry, Vol. 289, Issue 33, pp. 22771-84, (2014) (PubMed).

Samba-Louaka, Pereira, Nahori, Villiers, Deriano, Hamon, Cossart: "Listeria monocytogenes dampens the DNA damage response." in: PLoS pathogens, Vol. 10, Issue 10, pp. e1004470, (2014) (PubMed).

Aliases for MDC1 Antibodies

mediator of DNA damage checkpoint 1 (Mdc1) Antibodies
mediator of DNA damage checkpoint 1 (MDC1) Antibodies
mediator of DNA-damage checkpoint 1 (MDC1) Antibodies
6820401C03 Antibodies
AA413496 Antibodies
mKIAA0170 Antibodies
Nfbd1 Antibodies
NFBD1 Antibodies
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