Membrane Frizzled-Related Protein (MFRP) ELISA Kits

MFRP encodes a member of the frizzled-related proteins. Additionally we are shipping MFRP Antibodies (17) and MFRP Proteins (6) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
MFRP 83552 Q9BY79
Anti-Rat MFRP MFRP 315597  
MFRP 259172 Q8K480
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Top MFRP ELISA Kits at

Showing 3 out of 6 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Delivery Price Details
  96 Tests 31 to 41 Days
  96 Tests 26 to 36 Days
Mouse < 46.9 pg/mL 78 pg/mL - 5000 pg/mL   96 Tests 11 to 18 Days

More ELISA Kits for MFRP Interaction Partners

Human Membrane Frizzled-Related Protein (MFRP) interaction partners

  1. We report the MFRP-related ocular phenotype in three siblings with glycogen storage disease type 1b. Molecular genetic studies identified novel mutations in the MFRP and SLC37A4 genes.

  2. The current study expands our knowledge of the mutation spectrum of MFRP and its associated phenotypes. To our knowledge, this is the first report of MFRP mutations in a Chinese cohort.

  3. Among five single nucleotide polymorphism(SNP)s tested, only MFRP rs3814762 and heat shock protein (HSP)70 rs1043618 show nominal association with primary angle closure.

  4. nanophthalmos and high hyperopia but without electrophysiological evidence of retinal dystrophy has also been associated with MFRP mutations.

  5. Corneal diameter decreases with decreasing axial length, suggesting posterior microphthalmos and nanophthalmos represent a spectrum of high hyperopia rather than distinct phenotypes. In the Saudi population PRSS56 mutations are the major cause.

  6. Homozygous autosomal recessive retinitis pigmentosa-causing mutations have been found in three Indian families. These included a single base deletion in MFRP.

  7. MFRP gene shows tendency to be associated with primary angle closure glaucoma in both the Australian and Nepalese cohorts.

  8. Posterior microphthalmos can be caused by nonsense compound heterozygous mutations in the MFRP gene.

  9. In both previous reports of PMPRS, mutations in membrane type frizzled-related protein (MFRP) gene (located at 11q23) was demonstrated to be present

  10. Three novel MFRP mutations that expand the phenotypic data available on patients with MFRP mutations, are reported.

  11. Extreme hyperopia (Nanophthalmos) is the result of null mutations in MFRP.

  12. Mutation of the membrane-type frizzled-related protein gene is associated with inherited retinal degenerations

  13. Defects in MFRP could be responsible for syndromic forms of microphthalmos/retinal degeneration. This gene is necessary for photoreceptor maintenance.

  14. These results indicate that the MFRP gene may not play a role in regulating ocular axial length in these phenotypes.

  15. Patients without MFRP gene function exhibit no correction of refractive error during childhood, which suggests that this gene is essential for emmetropization, a complex process by which vision regulates axial growth of the eye.

  16. The novel frameshift mutation identified in the family described here validates MFRP as the gene responsible for this particular disease, which characteristically involves structures located at the posterior segment of the eye.

  17. These results do not support a significant role for CHX10 or MFRP mutations in primary angle closure glaucoma.

  18. Significant associations between angle-closure glaucoma and sequence variants in the MFRP gene, was analyzed.

  19. MFRP is less likely to play a major role in physiologic high hyperopia.

  20. This is the first demonstration of compound heterozygosity for MFRP mutations.

Mouse (Murine) Membrane Frizzled-Related Protein (MFRP) interaction partners

  1. Transcripts of Prss56, a gene associated with angle-closure glaucoma, posterior microphthalmia and myopia, were increased in Mfrprd6 eyes by 17-fold.

  2. the severity of the Mfrp(rd6) retinal degenerative phenotype in mice depends on the strain genetic background and that a significant modifier locus on CAST/EiJ Chromosome 1 protects against Mfrp(rd6)-associated photoreceptor loss.

  3. The authors have identified a novel null mutation in mouse Mfrp. This mutation causes photoreceptor degeneration and eventual RPE atrophy, which may be related to alterations in the number of RPE microvilli.

  4. involvement of the Mfrp gene expressed by retinal pigment epithelium in the degeneration of photoreceptors

MFRP Antigen Profile

Antigen Summary

This gene encodes a member of the frizzled-related proteins. The encoded protein may play a role in eye development, as mutations in this gene have been associated with nanophthalmos, posterior microphthalmia, retinitis pigmentosa, foveoschisis, and optic disc drusen. The protein is encoded by a bicistronic mRNA, which also encodes C1q and tumor necrosis factor related protein 5.

Gene names and symbols associated with MFRP

  • C1q and TNF related 5 (C1QTNF5) antibody
  • membrane frizzled-related protein (MFRP) antibody
  • membrane frizzled-related protein (Mfrp) antibody
  • MCOP5 antibody
  • MFRP antibody
  • NNO2 antibody
  • rd6 antibody

Protein level used designations for MFRP

membrane frizzled-related protein , membrane frizzled-related protein-like , membrane-type frizzled-related protein

451609 Pan troglodytes
704965 Macaca mulatta
100071432 Equus caballus
100338785 Oryctolagus cuniculus
100398152 Callithrix jacchus
100454727 Pongo abelii
100465638 Ailuropoda melanoleuca
100597354 Nomascus leucogenys
83552 Homo sapiens
489366 Canis lupus familiaris
522979 Bos taurus
315597 Rattus norvegicus
259172 Mus musculus
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