anti-Membrane-Associated Ring Finger (C3HC4) 8, E3 Ubiquitin Protein Ligase (MARCH8) Antibodies

MARCH8 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). Additionally we are shipping MARCH8 Proteins (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MARCH8 220972 Q5T0T0
MARCH8 71779 Q9DBD2
MARCH8 312656  
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Top anti-MARCH8 Antibodies at antibodies-online.com

Showing 10 out of 54 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-MARCH8 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:12500  Positive Control:  Human Muscle 100 μL 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-MARCH8 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  PANC1 cell lysate MARCH8 is supported by BioGPS gene expression data to be expressed in PANC1 WB Suggested Anti-MARCH8  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500  Positive Control: PANC1 cell lysate  MARCH8 is supported by BioGPS gene expression data to be expressed in PANC1 100 μL 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-MARCH8 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  NCI-H226 cell lysate 100 μL 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, IF, IHC (p), WB Immunocytochemistry in HeLa cells with MARCH8 antibody at 2.5 µg/ml. Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg 6 to 8 Days
$495.00
Details
Bat Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated EIA, IF, WB   0.1 mg 4 to 8 Days
$522.50
Details
Human Rabbit Un-conjugated ELISA, ICC, IHC, IHC (p), WB Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE) 0.05 mg 11 to 14 Days
$484.00
Details
Human Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$551.83
Details
Cow Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated ICC, IHC (p), ELISA, WB 50 μg 12 to 14 Days
$686.14
Details

Top referenced anti-MARCH8 Antibodies

  1. Human Polyclonal MARCH8 Primary Antibody for ELISA, WB - ABIN566949 : Tada, Zhang, Koyama, Tobiume, Tsunetsugu-Yokota, Yamaoka, Fujita, Tokunaga: MARCH8 inhibits HIV-1 infection by reducing virion incorporation of envelope glycoproteins. in Nature medicine 2015 (PubMed)

More Antibodies against MARCH8 Interaction Partners

Human Membrane-Associated Ring Finger (C3HC4) 8, E3 Ubiquitin Protein Ligase (MARCH8) interaction partners

  1. Knockdown of MARCH8 inactivated the PI3K and ss-catenin stat3 signaling pathways by changing protein expression levels or the phosphorylation of related proteins and inhibited migration and invasion of MKN-45 and AGS cells.

  2. Two additional regulators of BST2 constitutive ubiquitylation and sorting to the lysosomes: the E3 ubiquitin ligases NEDD4 and MARCH8, are reported.

  3. Salmonella typhimurium SteD caused MARCH8-dependent ubiquitination and depletion of surface-localized mature MHC class II antigens.

  4. YopJ mediates Ser- and Lys-acetylation and affects auto-ubiquitination of ubiquitin ligase MARCH8 in human cells.

  5. Kaposi's sarcoma-associated herpesvirus RTA not only downregulated HLA-DRalpha at the protein level through direct binding and degradation through the proteasome pathway but also indirectly downregulated the protein level of HLA-DRalpha by enhancing the expression of MARCH8, a member of the membrane-associated RING-CH (MARCH) proteins.

  6. MARCH8 is highly expressed in terminally differentiated myeloid cells, and that it is a potent antiviral protein that targets viral envelope glycoproteins and reduces their incorporation into virions.

  7. MARCH 8 mediates the ubiquitination and lysosomal degradation of the transferrin receptor.

  8. MARCH8 protein localizes in lysosomes in HeLa cells

  9. endogenous MARCH-8 regulates the steady-state cell surface expression of TRAIL-R1.

  10. MARCH8-mediated polyubiquitination and degradation of IL1RAP is an important mechanism for negative regulation of IL-1beta-induced signaling pathways.

  11. MARCH8 expression led to direct ubiquitination of CD98 and routing of CD98 to late endosomes/lysosomes

  12. Membrane-Associated RING-CH proteins MARCH VIII and MARCH IV associate with Bap31 and target CD81 and CD44 to lysosomes

  13. c-MIR induced specific down-regulation of B7-2 surface expression through ubiquitination, rapid endocytosis, and lysosomal degradation

  14. Of the classifier's 11 informative genes, expression of MIR and WDR40 showed statistically significant increases for both Grade 1B and Grade >or=3A rejection.

Zebrafish Membrane-Associated Ring Finger (C3HC4) 8, E3 Ubiquitin Protein Ligase (MARCH8) interaction partners

  1. March 8 functions in the embryo to modulate the strength of cell adhesion by regulating the localization of E-cadherin.

Mouse (Murine) Membrane-Associated Ring Finger (C3HC4) 8, E3 Ubiquitin Protein Ligase (MARCH8) interaction partners

  1. orchestrated regulation of MHC II surface expression in thymic epithelial cells by MARCH 8 and CD83 plays a major role in CD4(+) T cell selection.

  2. CD83-mediated MHCII stabilization through antagonism of March8 as a novel functional adaptation of cortical epithelial cells for T cell selection.

MARCH8 Antigen Profile

Protein Summary

MARCH8 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH8 induces the internalization of several membrane glycoproteins (Goto et al., 2003

Gene names and symbols associated with MARCH8

  • membrane associated ring-CH-type finger 8 (MARCH8) antibody
  • membrane-associated ring finger (C3HC4) 8 (march8) antibody
  • membrane-associated ring finger (C3HC4) 8 (March8) antibody
  • membrane associated ring-CH-type finger 8 (March8) antibody
  • membrane associated ring-CH-type finger 8 (march8) antibody
  • membrane associated ring-CH-type finger 8 L homeolog (march8.L) antibody
  • 1300017E09Rik antibody
  • c-MIR antibody
  • Mar-08 antibody
  • MARCH-VIII antibody
  • MARCH8 antibody
  • Mir antibody
  • RNF178 antibody
  • zgc:171495 antibody

Protein level used designations for MARCH8

E3 ubiquitin-protein ligase MARCH8 , RING finger protein 178 , c-mir, cellular modulator of immune recognition , cellular modulator of immune recognition (c-MIR) , membrane-associated RING finger protein 8 , membrane-associated RING-CH protein VIII , MARCH-VIII , cellular modulator of immune recognition , membrane-associated ring finger (C3HC4) 8

GENE ID SPECIES
220972 Homo sapiens
567818 Danio rerio
71779 Mus musculus
312656 Rattus norvegicus
423770 Gallus gallus
448095 Xenopus (Silurana) tropicalis
450431 Pan troglodytes
495072 Xenopus laevis
540667 Bos taurus
606989 Canis lupus familiaris
100062110 Equus caballus
100221220 Taeniopygia guttata
Selected quality suppliers for anti-MARCH8 (MARCH8) Antibodies
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