MARCH8 antibody (AA 232-291)

Catalog No. ABIN6143551

This Rabbit Polyclonal antibody specifically detects MARCH8 in WB. It exhibits reactivity toward Human.

Quick Overview for MARCH8 antibody (AA 232-291) (ABIN6143551)

Target: MARCH8 (Membrane-Associated Ring Finger (C3HC4) 8, E3 Ubiquitin Protein Ligase (MARCH8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MARCH8 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MARCH8 Antibody

Binding Specificity: AA 232-291

Sequence: YNRVIYVQNC PETSKKNIFE KSPLTEPNFE NKHGYGICHS DTNSSCCTEP EDTGAEIIHV

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 232-291 of human MARCH8 (NP_659458.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MARCH8

Target: MARCH8 (Membrane-Associated Ring Finger (C3HC4) 8, E3 Ubiquitin Protein Ligase (MARCH8))

Alternative Name: 8-Mar

Background: MARCH8 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH8 induces the internalization of several membrane glycoproteins (Goto et al., 2003 [PubMed 12582153], Bartee et al., 2004 [PubMed 14722266]).,MARCH8,CMIR,MARCH-VIII,MIR,RNF178,c-MIR,Cell Biology & Developmental Biology,Ubiquitin,Immunology & Inflammation,8-Mar

Molecular Weight: 32 kDa/63 kDa

Gene ID: 220972

UniProt: Q5T0T0