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This protein is ubiquitous and highly conserved. Additionally we are shipping MSRA Proteins (70) and MSRA Kits (17) and many more products for this protein.
Showing 10 out of 54 products:
Human Polyclonal MSRA Primary Antibody for ICC, IF - ABIN4333966
Shin, Yoon, Chun, Shin, Lee, Oh, Park: Arrest defective 1 regulates the oxidative stress response in human cells and mice by acetylating methionine sulfoxide reductase A. in Cell death & disease 2014
MsrA (show MSR1 Antibodies) protects against lipopolysaccharide-induced septic shock, and negatively regulates proinflammatory responses via inhibition of the ROS (show ROS1 Antibodies)-MAPK (show MAPK1 Antibodies)-NF-kappaB (show NFKB1 Antibodies) signaling pathways.
Collectively, our results suggest that MsrA (show MSR1 Antibodies) protects hepatocytes from APAP-induced cytotoxicity through the modulation of TXNRD1 (show TXNRD1 Antibodies) expression.
results demonstrate that MsrA (show MSR1 Antibodies) protects the liver from APAP-induced toxicity. The data provided herein constitute the first in vivo evidence of the involvement of MsrA (show MSR1 Antibodies) in hepatic function under APAP challenge
Results suggest that lower MsrA (show MSR1 Antibodies) activity modifies Amyloid-beta solubility properties and causes mitochondrial dysfunction in a mouse model of Alzheimer's disease.
MsrA (show MSR1 Antibodies) acts as a negative regulator of vascular smooth muscle cell proliferation and neointimal hyperplasia after vascular injury through control of the Ras/Raf (show RAF1 Antibodies)/ERK1 (show MAPK3 Antibodies)/ERK2 (show MAPK1 Antibodies) signaling pathway.
ARD1 (show ARD1A Antibodies) has a crucial role in the cellular response to oxidative stress as a bona fide regulator of MSRA (show MSR1 Antibodies).
These results suggest that COMT (show COMT Antibodies) activity may be reduced by methionine oxidation, and point to Msr (show MSR1 Antibodies) as a key molecular determinant for the modulation of COMT (show COMT Antibodies) activity in the brain.
The MsrA (show MSR1 Antibodies) and protein oxidation play a role in the regulation of glucose homeostasis.
MsrA (show MSR1 Antibodies) protects the kidney against I/R injury, and that this protection is associated with reduced oxidative stress and inflammatory responses.
MsrA (show MSR1 Antibodies) overexpression in MsrA (show MSR1 Antibodies)-depleted cells led to the reduction of increased HO-1 (show HMOX1 Antibodies) expression, and suppressed nuclear accumulation of Nrf2 (show NFE2L2 Antibodies).
Data show that miR (show MLXIP Antibodies)-193b, by directly targeting focal adhesion kinase (FAK), CRK (show CRK Antibodies)-like proto-oncogene (show RAB1A Antibodies) (CRKL (show CRKL Antibodies)), and methionine sulfoxide reductase A (MSRA), regulates focal adhesion signaling and ROS (show ROS1 Antibodies) signaling, which play pivotal roles in liposarcomagenesis and adipogenic differentiation.
this study we have identified, for the first time, compounds structurally related to the natural products fusaricidins that markedly activate recombinant bovine and human MsrA and human MsrB (show MSRB2 Antibodies).
The association of MsrA haplotypes with executive functions indicated that MsrA is associated with executive function defects in bipolar I disorder patients.
Silencing the expression of the main Msr elements-MsrA, MsrB1, or MsrB2 exacerbates sensitivity toward oxidative stress.
ARD1 (show TRIM23 Antibodies) has a crucial role in the cellular response to oxidative stress as a bona fide regulator of MSRA.
The functional MSRA rs10903323 G/A polymorphism is associated with coronary artery disease development.
We hypothesize that the activity of MsrA can be employed as a marker for the isolation of stem and progenitor cell subpopulations for cell therapy applications.
The MSRA rs10903323 G/A variant allele is associated with Rheumatoid Arthritis development, especially among male patients, older patients, C-Reactive Protein (show CRP Antibodies)-positive patients, and anti-cyclic citrullinated peptide negative patients.
The MSRA rs10903323 gene polymorphism may be implicated in the increased risk to develop cardiovascular events, in particular ischaemic heart disease, observed in rheumatoid arthritis patients.
Mammalian and yeast MSRA reduced free methionine sulfoxide much more efficiently than MSRB (show MSRB2 Antibodies).
The results indicate that thionein (T), which is formed when the zinc is removed from zinc-containing metallothionein (show MT Antibodies) (Zn-MT), can function as a reducing system for the Msr (show MTRR Antibodies) proteins because of its high content of cysteine residues.
This protein is ubiquitous and highly conserved. It carries out the enzymatic reduction of methionine sulfoxide to methionine. Human and animal studies have shown the highest levels of expression in kidney and nervous tissue. Its proposed function is the repair of oxidative damage to proteins to restore biological activity. Three transcript variants encoding different isoforms have been found for this gene.
, mitochondrial peptide methionine sulfoxide reductase
, peptide Met(O) reductase
, peptide methionine sulfoxide reductase
, peptide-methionine (S)-S-oxide reductase
, protein-methionine-S-oxide reductase
, cytosolic methionine-S-sulfoxide reductase
, peptide met (O) reductase