anti-Methionine Sulfoxide Reductase A (MSRA) Antibodies

This protein is ubiquitous and highly conserved. Additionally we are shipping MSRA Proteins (72) and MSRA Kits (20) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MSRA 110265 Q9D6Y7
MSRA 29447 Q923M1
MSRA 4482 Q9UJ68
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Top anti-MSRA Antibodies at antibodies-online.com

Showing 10 out of 65 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Dog Rabbit Un-conjugated IHC, WB Rabbit Anti-MSRA Antibody Catalog Number: ARP56732_P050 Formalin Fixed Paraffin Embedded Tissue: Human heart Tissue Observed Staining: Cytoplasmic Primary Antibody Concentration: N/A Other Working Concentrations: 1:600 Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0.5 - 2.0 sec WB Suggested Anti-MSRA Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: Human Lung 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated FACS, IF, IHC (p), WB Western blot analysis of MSRA antibody (N-term) (ABIN391489) in mouse kidney tissue lysates (35 µg/lane). MSRA (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with MSRA Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$385.00
Details
Cow Rabbit Un-conjugated WB Host: Rabbit Target Name: MSRA Sample Type: HT1080 Whole Cell lysates Antibody Dilution: 1.0ug/ml  MSRA is supported by BioGPS gene expression data to be expressed in HT1080 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Human Kidney, Tubules: Formalin-Fixed, Paraffin-Embedded (FFPE) Anti-MSRA antibody IHC of human kidney, tubules. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200. 50 μL Log in to see 11 to 14 Days
$484.00
Details
Human Mouse Un-conjugated IF, IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to MSRA on formalin-fixed paraffin-embedded human salivary gland. [antibody concentration 3 ug/ml] Detection limit for recombinant GST tagged MSRA is 1 ng/ml as a capture antibody. 50 μg Log in to see 11 to 12 Days
$364.00
Details
Human Rabbit Un-conjugated IHC (p), WB Human Kidney, Tubules: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL Log in to see 6 to 8 Days
$495.00
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Western Blot: Methionine Sulfoxide Reductase A Antibody [NBP1-87456] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.Lane 2: Human cell line RT-4.Lane 3: Human cell line U-251MG sp Immunohistochemistry-Paraffin: Methionine Sulfoxide Reductase A Antibody [NBP1-87456] - Staining of human kidney shows moderate cytoplasmic positivity in cells in tubules. 0.1 mL Log in to see 10 to 13 Days
$494.38
Details
Human Rabbit Un-conjugated ICC, IHC, WB Western Blot; Sample: Human HT1080 cell lysate; Primary Ab: 3µg/ml Rabbit Anti-Human MSRA Antibody Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: SAA544Rb19) Figure. Western Blot; Sample: Recombinant protein. 100 μg Log in to see 13 to 16 Days
$350.00
Details
Human Mouse Un-conjugated IP 100 μL Log in to see 11 to 14 Days
$463.83
Details
Human Mouse Un-conjugated IP 100 μL Log in to see 11 to 14 Days
$463.83
Details

Top referenced anti-MSRA Antibodies

  1. Human Polyclonal MSRA Primary Antibody for WB - ABIN540272 : Sun, Gao, Ferrington, Biesiada, Williams, Squier: Repair of oxidized calmodulin by methionine sulfoxide reductase restores ability to activate the plasma membrane Ca-ATPase. in Biochemistry 1999 (PubMed)
    Show all 3 Pubmed References

  2. Human Monoclonal MSRA Primary Antibody for IHC (fro), IP - ABIN532608 : Gabbita, Aksenov, Lovell, Markesbery: Decrease in peptide methionine sulfoxide reductase in Alzheimer's disease brain. in Journal of neurochemistry 1999 (PubMed)
    Show all 3 Pubmed References

  3. Human Monoclonal MSRA Primary Antibody for IP - ABIN532607 : Davis, Newcomb, Moskovitz, Wingfield, Stahl, Kaufman, Fales, Levine, Yarchoan: HIV-2 protease is inactivated after oxidation at the dimer interface and activity can be partly restored with methionine sulphoxide reductase. in The Biochemical journal 2000 (PubMed)
    Show all 3 Pubmed References

  4. Human Polyclonal MSRA Primary Antibody for ICC, IF - ABIN4333966 : Shin, Yoon, Chun, Shin, Lee, Oh, Park: Arrest defective 1 regulates the oxidative stress response in human cells and mice by acetylating methionine sulfoxide reductase A. in Cell death & disease 2014 (PubMed)

More Antibodies against MSRA Interaction Partners

Mouse (Murine) Methionine Sulfoxide Reductase A (MSRA) interaction partners

  1. Our findings demonstrate that reversal of methionine oxidation is required for maintenance of cellular homeostasis in the absence of increased oxidative stress. These data provide the first link between autophagy and activation of Nrf2 in the setting of MsrA deletion

  2. Study shows that cisplatin induces methionine oxidation, oxidative stress, mitochondrial damage, apoptosis, and necrosis, and that MsrA gene deletion accelerates these cisplatin-induced damages. This indicates that MsrA protects kidney against cisplatin-induced acute kidney injury.

  3. MsrA protects against lipopolysaccharide-induced septic shock, and negatively regulates proinflammatory responses via inhibition of the ROS-MAPK-NF-kappaB signaling pathways.

  4. Collectively, our results suggest that MsrA protects hepatocytes from APAP-induced cytotoxicity through the modulation of TXNRD1 expression.

  5. results demonstrate that MsrA protects the liver from APAP-induced toxicity. The data provided herein constitute the first in vivo evidence of the involvement of MsrA in hepatic function under APAP challenge

  6. Results suggest that lower MsrA activity modifies Amyloid-beta solubility properties and causes mitochondrial dysfunction in a mouse model of Alzheimer's disease.

  7. MsrA acts as a negative regulator of vascular smooth muscle cell proliferation and neointimal hyperplasia after vascular injury through control of the Ras/Raf/ERK1/ERK2 signaling pathway.

  8. ARD1 has a crucial role in the cellular response to oxidative stress as a bona fide regulator of MSRA.

  9. These results suggest that COMT activity may be reduced by methionine oxidation, and point to Msr as a key molecular determinant for the modulation of COMT activity in the brain.

  10. The MsrA and protein oxidation play a role in the regulation of glucose homeostasis.

  11. MsrA protects the kidney against I/R injury, and that this protection is associated with reduced oxidative stress and inflammatory responses.

  12. MsrA overexpression in MsrA-depleted cells led to the reduction of increased HO-1 expression, and suppressed nuclear accumulation of Nrf2.

  13. Mammalian and yeast Msra reduced free methionine sulfoxide much more efficiently than Msrb.

  14. Data show that glutaredoxin acts as a reductant for methionine sulfoxide reductases A and B (MsrA and MsrB) with or without resolving cysteine.

  15. Characterization and solution structure of mouse myristoylated methionine sulfoxide reductase A.

  16. A low pKa cysteine at the active site of mouse methionine sulfoxide reductase A.

  17. The data suggest that MsrA is a regulator of cell growth that mediates the p53-p21 pathway.

  18. MsrA-/- knockout mice maintain a larger brain dopamine reserve pool than wild-type control mice, a difference not likely caused by altered dopamine transporter expression.

  19. We conclude that cytosolic MsrA protects the heart from ischemia-reperfusion damage

  20. A c-terminal truncated form of MsrA was cloned from mouse embryonic stem cells. The truncated protein shows a different subcellular localization and pattern of expression response to anoxia/reoxygenation treatment on the stem cells.

Human Methionine Sulfoxide Reductase A (MSRA) interaction partners

  1. myristoylated MSRA is a late endosomal protein that may play a role in lipid metabolism or may protect endosomal proteins from oxidative damage.

  2. Data show that miR-193b, by directly targeting focal adhesion kinase (FAK), CRK-like proto-oncogene (CRKL), and methionine sulfoxide reductase A (MSRA), regulates focal adhesion signaling and ROS signaling, which play pivotal roles in liposarcomagenesis and adipogenic differentiation.

  3. this study we have identified, for the first time, compounds structurally related to the natural products fusaricidins that markedly activate recombinant bovine and human MsrA and human MsrB.

  4. The association of MsrA haplotypes with executive functions indicated that MsrA is associated with executive function defects in bipolar I disorder patients.

  5. Silencing the expression of the main Msr elements-MsrA, MsrB1, or MsrB2 exacerbates sensitivity toward oxidative stress.

  6. ARD1 has a crucial role in the cellular response to oxidative stress as a bona fide regulator of MSRA.

  7. The functional MSRA rs10903323 G/A polymorphism is associated with coronary artery disease development.

  8. We hypothesize that the activity of MsrA can be employed as a marker for the isolation of stem and progenitor cell subpopulations for cell therapy applications.

  9. The MSRA rs10903323 G/A variant allele is associated with Rheumatoid Arthritis development, especially among male patients, older patients, C-Reactive Protein-positive patients, and anti-cyclic citrullinated peptide negative patients.

  10. The MSRA rs10903323 gene polymorphism may be implicated in the increased risk to develop cardiovascular events, in particular ischaemic heart disease, observed in rheumatoid arthritis patients.

  11. Mammalian and yeast MSRA reduced free methionine sulfoxide much more efficiently than MSRB.

  12. Data show that glutaredoxin acts as a reductant for methionine sulfoxide reductases A and B (MsrA and MsrB) with or without resolving cysteine.

  13. The haplotype with the lowest P value showed association with Meconium ileus in an independent sample of 1,335 unrelated cystic fibrosis patients

  14. The MSRA gene located on chromosome 8 was found to be associated with the phenotype of schizophrenia in Chinese first-episode schizophrenia patients.

  15. central obesity-associated variants in LYPLAL1, NRXN3, MSRA, and TFAP2B

  16. Data suggest a critical role for TXNL6 in MsrA repair of essential lens proteins under oxidative stress conditions and that TXNL6 is important for MsrA defense protection against cataract.

  17. Our findings indicate that a novel association in the MSRA gene is related to oxidative stress and support the notion of a major role for this process in rheumatoid arthritis.

  18. reduction of MsrA levels results in increased cell proliferation and extracellular matrix degradation, and consequently in a more aggressive cellular phenotype in breast cancer cells

  19. Dual sites of protein initiation control the localization and myristoylation of methionine sulfoxide reductase A

  20. protein-specific autoantibody are associated with pulmonary fibrosis and renal vascular damage in systemic sclerosis

Cow (Bovine) Methionine Sulfoxide Reductase A (MSRA) interaction partners

  1. The results indicate that thionein (T), which is formed when the zinc is removed from zinc-containing metallothionein (Zn-MT), can function as a reducing system for the Msr proteins because of its high content of cysteine residues.

MSRA Antigen Profile

Protein Summary

This protein is ubiquitous and highly conserved. It carries out the enzymatic reduction of methionine sulfoxide to methionine. Human and animal studies have shown the highest levels of expression in kidney and nervous tissue. Its proposed function is the repair of oxidative damage to proteins to restore biological activity. Three transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with MSRA

  • methionine sulfoxide reductase A (Msra) antibody
  • methionine sulfoxide reductase A (MSRA) antibody
  • 2310045J23Rik antibody
  • 6530413P12Rik antibody
  • MSR-A antibody
  • PMSR antibody

Protein level used designations for MSRA

PMSR , mitochondrial peptide methionine sulfoxide reductase , peptide Met(O) reductase , peptide methionine sulfoxide reductase , peptide-methionine (S)-S-oxide reductase , protein-methionine-S-oxide reductase , cytosolic methionine-S-sulfoxide reductase , peptide met (O) reductase

GENE ID SPECIES
110265 Mus musculus
29447 Rattus norvegicus
4482 Homo sapiens
281312 Bos taurus
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