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Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 2, Methenyltetrahydrofolate Cyclohydrolase Proteins

MTHFD2 encodes a nuclear-encoded mitochondrial bifunctional enzyme with methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities.

Data Quality
  • 7
Type
  • 9
    Protein
Antigen
  • 9
Reactivity
  • 7
  • 1
  • 1
Application
  • 5
  • 4
  • 4
  • 2
  • 2
Host
  • 6
  • 1
  • 1
  • 1
Binding Specificity
  • 3
  • 2
  • 1
  • 1
Conjugate
  • 1
  • 6
  • 1
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Protein Type
  • 9
Format
  • 5
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9 Products
Recombinant Protein, Escherichia coli (E. coli) (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityMouse (Murine)
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3133176
$5,227.64
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 30 to 35 Business Days
Recombinant Protein, Escherichia coli (E. coli) (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityHuman
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3083919
$5,227.64
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 30 to 35 Business Days
Recombinant Protein, Escherichia coli (E. coli) (Source), Purity > 95 % pure
ReactivityHuman
Application SDS
Order details Cat. No. ABIN5623895
$440.14
100 μg
Plus shipping costs $45.00
Delivery in 9 to 11 Business Days
Recombinant Protein, Escherichia coli (E. coli) (Source), Purity > 80 % as determined by SDS-PAGE and Coomassie blue staining
ReactivityHuman
Application AbP, Func, PI, STD
Order details Cat. No. ABIN2725876
$302.50
50 μg
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 11 Business Days
Recombinant Protein, Wheat germ (Source)
ISO
ReactivityHuman
Application AP, AA, ELISA, WB
Order details Cat. No. ABIN1311558
$414.29
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 11 to 12 Business Days
Recombinant Protein, Escherichia coli (E. coli) (Source), Purity >95 %
ReactivityHuman
Application MS, ELISA, WB
Order details Cat. No. ABIN2468871
$515.63
0.05 mg
Plus shipping costs $45.00
Delivery in 2 to 3 Business Days
Recombinant Protein, Escherichia coli (E. coli) (Source), Purity > 95 % by SDS - PAGE
ReactivityHuman
Application SDS
Order details Cat. No. ABIN5854086
$553.85
Plus shipping costs $45.00
Delivery in 13 to 16 Business Days
Recombinant Protein, HEK-293 Cells (Source), Purity > 80 % as determined by SDS-PAGE and Coomassie blue staining
ReactivityHuman
Application AbP, Func, PI, STD
Order details Cat. No. ABIN2726508
$888.80
20 μg
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 11 Business Days
Recombinant Protein, Yeast (Source), Purity > 90 %
ReactivityCow (Bovine)
Application ELISA
Order details Cat. No. ABIN1617699
$2,843.50
1 mg
Plus shipping costs $45.00
Delivery in 60 to 71 Business Days
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Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 2, Methenyltetrahydrofolate Cyclohydrolase (MTHFD2) Protein Profile

Protein Summary

This gene encodes a nuclear-encoded mitochondrial bifunctional enzyme with methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities. The enzyme functions as a homodimer and is unique in its absolute requirement for magnesium and inorganic phosphate. Formation of the enzyme-magnesium complex allows binding of NAD. Alternative splicing results in two different transcripts, one protein-coding and the other not protein-coding. This gene has a pseudogene on chromosome 7.

Gene names and symbols associated with MTHFD2

  • methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase L homeolog (mthfd2.L) antibody
  • methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase (MTHFD2) antibody
  • methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase (mthfd2) antibody
  • methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like S homeolog (mthfd2l.S) antibody
  • methylenetetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase (Mthfd2) antibody
  • methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase (Mthfd2) antibody
  • AW558851 antibody
  • NMDMC antibody
  • wu:fb38b11 antibody
  • wu:fe12e11 antibody
  • zgc:91891 antibody

Protein level used designations for MTHFD2

bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial , methylene tetrahydrofolate dehydrogenase 2 , methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase , methylenetetrahydrofolate dehydrogenase 2 , NAD-dependent methylene tetrahydrofolate dehydrogenase cyclohydrolase , methylene tetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase , methylenetetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase

GENE ID SPECIES
432317 Xenopus laevis
459331 Pan troglodytes
100053990 Equus caballus
100170462 Xenopus (Silurana) tropicalis
100584729 Nomascus leucogenys
446641 Xenopus laevis
17768 Mus musculus
426126 Gallus gallus
10797 Homo sapiens
483107 Canis lupus familiaris
517539 Bos taurus
680308 Rattus norvegicus
100004977 Danio rerio
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