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Microfibrillar-associated protein 2 is a major antigen of elastin-associated microfibrils and a candidate for involvement in the etiology of inherited connective tissue diseases. Additionally we are shipping MFAP2 Proteins (14) and many more products for this protein.
Showing 10 out of 46 products:
Human Polyclonal MFAP2 Primary Antibody for WB - ABIN4891777
Zheng, Chen, Chen, Lyga, Wyborski, Santhanam: Investigation of age-related decline of microfibril-associated glycoprotein-1 in human skin through immunohistochemistry study. in Clinical, cosmetic and investigational dermatology 2013
Our characterization of alternative forms of MAGP2 (show MFAP5 Antibodies) present in the extracellular space not only enhances diversity of this ECM (show MMRN1 Antibodies) protein but also provides a previously unrecognized molecular mechanism for regulation of MAGP2 (show MFAP5 Antibodies) biological activity.
Decreased MFAP2 gene expression in the endometrium of patients with implantation failure after in vitro ertilization treatment.
Demonstrate specific immunolocalization of fibrillin-1 (show FBN1 Antibodies), MAGP-1, and LTBP-1 (show LTBP1 Antibodies) with elastin (show ELN Antibodies) in the outer annulus fibrosus of the fetal human intravertebral disc.
These results demonstrate that microfibril-associated glycoprotein-1 is capable of cumulative binding to distinct regions on tropoelastin (show ELN Antibodies), with different apparent dissociation constants and different amounts of bound protein.
microfibrillar proteins MAGP-1 and MAGP-2 (show MFAP5 Antibodies) can function outside of their role in elastic fibers to activate a cellular signaling pathway
Study suggests a dual role for MAGP1, with extracellular MAGP1A involved in ECM (show MMRN1 Antibodies) function, and intracellular MAGP1B modulating the expression of genes that function in cell adhesion, migration and control of ECM (show MMRN1 Antibodies) deposition.
Findings indicate that the regulation of TGF-beta (show TGFB1 Antibodies) by MAGP1 is protective against the effects of metabolic stress, and its absence predisposes individuals to metabolic dysfunction.
These studies provide support for increased RANKL (show TNFSF11 Antibodies) expression associated with MAGP1 deficiency and provide a link to altered TGF-beta (show TGFB1 Antibodies) signaling as a possible causative signaling pathway regulating RANKL (show TNFSF11 Antibodies) expression in MAGP1-deficient osteoblasts.
MAGP1 is a regulator of bone remodeling, and its absence results in osteopenia associated with an increase in osteoclast number
These findings show that MAGP1, a component of microfibrils and vascular elastic fibers, plays a role in hemostasis and thrombosis.
microfibril-associated glycoprotein-1 has a role in complex phenotypes in multiple organ systems
Microfibrillar-associated protein 2 is a major antigen of elastin-associated microfibrils and a candidate for involvement in the etiology of inherited connective tissue diseases. Four transcript variants encoding two different isoforms have been found for this gene.
microfibril-associated glycoprotein 1
, tropoelastin-binding protein