Microtubule Associated Protein 6 Proteins (MAP6)

MAP6 encodes a microtubule-associated protein. Additionally we are shipping MAP6 Antibodies (11) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MAP6 4135 Q96JE9
MAP6 17760 Q7TSJ2
Rat MAP6 MAP6 29457 Q63560
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Top MAP6 Proteins at antibodies-online.com

Showing 5 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
$13,741.67
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Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
$13,741.67
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Escherichia coli (E. coli) Mouse His tag,T7 tag 100 μg Log in to see 15 to 18 Days
$717.00
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Yeast Chicken His tag   1 mg Log in to see 60 to 71 Days
$3,010.33
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Yeast Xenopus tropicalis His tag   1 mg Log in to see 60 to 71 Days
$3,039.67
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MAP6 Proteins by Origin and Source

Origin Expressed in Conjugate
Human

Mouse (Murine) ,
,

More Proteins for Microtubule Associated Protein 6 (MAP6) Interaction Partners

Human Microtubule Associated Protein 6 (MAP6) interaction partners

  1. the concentration of STOP/MAP6 protein was significantly reduced in the plasma of autistic subjects than that in healthy controls.

  2. These data show that TMEM106B/MAP6 interaction is crucial for controlling dendritic trafficking of lysosomes, presumably by acting as a molecular brake for retrograde transport.

  3. Structural basis for the association of MAP6 protein with microtubules and its regulation by calmodulin.

  4. MAP6 might serve as a temperature sensor adapting its conformation according to the temperature to maintain the cellular microtubule network in organisms exposed to temperature decrease.

  5. Using shotgun mass spectrometry, we found this protein differentially expressed in the dorsolateral prefrontal cortex from patients with schizophrenia.

Mouse (Murine) Microtubule Associated Protein 6 (MAP6) interaction partners

  1. MAP6 is involved in the formation and the maintenance of mature post-synaptic dendritic spines.MAP6 is involved in the stabilisation of actin filaments in dendritic spines.

  2. MAP6 deletion results in alterations of microtubule network, sarcoplasmic reticulum organization and calcium release.

  3. show that MAP6 proteins interact directly with both Tctex1 and the C-terminus of Cav2.2/N-type calcium channels.

  4. MAP6 is present at the Golgi complex and in secretory vesicles in unpolarized cells and re-distributed to newly forming axons, where it binds and stabilizes axonal microtubules. A palmitoylation cycle controls MAP6 membrane-microtubule shuttling and is required for its polarized distribution in axons.

  5. Mice deficient in stable tubule only polypeptide (STOP) show sleep/wake patterns that resemble those seen in patients with schizophrenia.

  6. MAP6 deletion disrupts brain connectivity and is associated with a lack of post-commissural fornix fibres. MAP6 contributes to fornix development by regulating axonal elongation induced by Semaphorin 3E.

  7. STOP/Map6 knockout mice are a valid model for cognitive deficits in schizophrenia.

  8. MAP6 might serve as a temperature sensor adapting its conformation according to the temperature to maintain the cellular microtubule network in organisms exposed to temperature decrease.

  9. Deletion of STOP protein in mice causes deep alterations in mood and cognitive performance and indicates that STOP protein might have a crucial role in the development of serotonin and norepinephrine networks.

  10. STOP null mice displayed elevated levels of endogenous morphine, as well as an increase of morphine receptor affinity and density in brain. This was correlated with hypernociception and impaired pharmacological sensitivity to mu opioid receptor ligands

  11. Loss of STOP protein impairs peripheral olfactory neurogenesis.

  12. Deletion of the STOP protein elicits an imbalance in serotonin neurotransmission and reduces anxiety in STOP knock-out mice.

  13. the study suggest D. alpha enhances the novel objective recognition task performance of STOP null mice by increasing production of nitric oxide.

  14. STOP protein localization and content in muscle cells was also muscle type-specific.

  15. STOP-/- mice had no detectable defects in brain anatomy but showed synaptic defects, with depleted synaptic vesicle pools and impaired synaptic plasticity, associated with severe behavioral disorders.

  16. interacts with neuronal tubulin independently of polyglutamylation

  17. there is a single neuronal specific promoter for transcription of E- and N-STOP mRNAs. F-STOP mRNA transcription is regulated by a distinct promoter that lies within coding sequences expressed in neuronal E- and N-STOP isoforms.

  18. Stop knockout mice disply a schizophrenia=like phenotype in both locomotor activity and PPI model.

  19. STOP phosphorylation by CaMKII may promote STOP translocation from microtubules to synaptic compartments where it may interact with actin, which could be important for STOP function in synaptic plasticity

  20. These results demonstrate that both STOP and MBP function as microtubule-stabilizing proteins in differentiating oligodendrocytes and could be important for the morphogenetic function of MBP.

MAP6 Protein Profile

Protein Summary

This gene encodes a microtubule-associated protein. The encoded protein is a calmodulin-binding and calmodulin-regulated protein that is involved in microtubule stabilization. Two transcript variants encoding distinct isoforms have been identified for this gene.

Gene names and symbols associated with MAP6

  • microtubule associated protein 6 (MAP6)
  • microtubule-associated protein 6 (Map6)
  • microtubule associated protein 6 (Map6)
  • 2810411E12Rik protein
  • Map-6 protein
  • Mtap6 protein
  • N-STOP protein
  • NAU protein
  • STOP protein

Protein level used designations for MAP6

MAP-6 , stable tubule-only polypeptide , 145-kDa STOP , STOP , STOP145 , microtubule-associated protein 6 homolog , MAP-6 homolog , putative microtubule associated protein , stable tubule-only polypeptide homolog , LOW QUALITY PROTEIN: microtubule-associated protein 6 , microtubule-associated protein 6

GENE ID SPECIES
4135 Homo sapiens
17760 Mus musculus
29457 Rattus norvegicus
395753 Gallus gallus
100732630 Cavia porcellus
100519724 Sus scrofa
476803 Canis lupus familiaris
518794 Bos taurus
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