anti-Microtubule-Associated Protein, RP/EB Family, Member 2 (MAPRE2) Antibodies

The protein encoded by MAPRE2 shares significant homology to the adenomatous polyposis coli (APC) protein-binding EB1 gene family. Additionally we are shipping Microtubule-Associated Protein, RP/EB Family, Member 2 Proteins (10) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MAPRE2 10982 Q15555
MAPRE2 212307 Q8R001
MAPRE2 679221 Q3B8Q0
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Top anti-Microtubule-Associated Protein, RP/EB Family, Member 2 Antibodies at antibodies-online.com

Showing 10 out of 111 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated WB Host: Rabbit Target Name: MAPRE2 Sample Type: THP-1 Whole Cell lysates Antibody Dilution: 1.0ug/ml 100 μL 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-MAPRE2 Antibody Titration: 1.0 ug/ml Positive Control: COLO205 Whole Cell 100 μL 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated FACS, IF, IHC, IHC (p), WB 100 μL 11 to 14 Days
$522.50
Details
Chicken Rabbit Un-conjugated WB Western blot analysis of EB2 expression in HEK293T (A), Raw264.7 (B), H9C2 (C) whole cell lysates. 200 μL 13 to 14 Days
$487.50
Details
Human Mouse Un-conjugated FACS, IF, WB 100 μL 11 to 14 Days
$522.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of MAPRE2 Antibody (N-term) in CEM cell line lysates (35ug/lane). This demonstrates the MAPRE2 antibody detected the MAPRE2 protein (arrow). 0.4 mL 6 to 8 Days
$484.00
Details
Dog Mouse Un-conjugated FACS, IF, WB 100 μL 11 to 14 Days
$522.50
Details
Human Mouse Un-conjugated FACS, IF, IHC, WB Anti-MAPRE2 mouse monoclonal antibody (ABIN2454542) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY MAPRE2 (RC200259). HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MAPRE2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-MAPRE2. 0.1 mL 2 to 3 Days
$462.00
Details
Human Mouse Un-conjugated FACS, IF, WB HEK293T cells transfected with either RC200259 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-MAPRE2 antibody (ABIN2454584), and then analyzed by flow cytometry. Anti-MAPRE2 mouse monoclonal antibody (ABIN2454584) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY MAPRE2 (RC200259). 0.1 mL 2 to 3 Days
$462.00
Details
Bat Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$551.83
Details

Top referenced anti-Microtubule-Associated Protein, RP/EB Family, Member 2 Antibodies

  1. Bacillus Monoclonal MAPRE2 Primary Antibody for ICC, IF - ABIN533446 : Komarova, Lansbergen, Galjart, Grosveld, Borisy, Akhmanova: EB1 and EB3 control CLIP dissociation from the ends of growing microtubules. in Molecular biology of the cell 2005 (PubMed)

More Antibodies against Microtubule-Associated Protein, RP/EB Family, Member 2 Interaction Partners

Human Microtubule-Associated Protein, RP/EB Family, Member 2 (MAPRE2) interaction partners

  1. Aurora B and CDK1 temporally regulate the binding affinity of EB2 for microtubules, thereby ensuring kinetochore microtubule dynamics, proper mitotic progression and genome stability.

  2. Mutations in either TUBB or MAPRE2 cause circumferential skin creases Kunze type.

  3. EB2 is evidently important for initial microtubule reorganisation during epithelial polarisation, whereas its downregulation facilitates EB1 and ACF7 microtubule lattice association, microtubule-actin filament co-alignment and bundle formation.

  4. results suggest that EB1 and ClipCG12 act cooperatively to regulate microtubule dynamics (EB1)

  5. heterodimer formation between EB1 and EB3, but not between EB2 and the other two EBs, occurs both in vitro and in cells as revealed by live cell imaging

  6. Data suggest that a functional interaction between EB1 and p150(Glued) is required for microtubule minus end anchoring at centrosomes during the assembly and maintenance of a radial microtubule array.

  7. EB1 may modulate kinetochore microtubule polymerization and/or attachment

  8. results support the novel hypothesis that EB1 overexpression may play a role in the development of esophageal squamous cell carcinoma by affecting APC function and activating the beta-catenin/TCF pathway

  9. Impaired EB1 or APC function generates lesions invisible to the spindle checkpoint and thereby promotes low levels of chromosomal loss (CIN) expected to fuel aneuploidy and possibly tumorigenesis.

  10. These data demonstrate that the COP9 signalosome-dependent protection of EB1 is important for microtubule function.

  11. Crystal structures of the tubulin binding domains of XMAP215 (yeast Stu2p and Drosophila Msps), EB1 (yeast Bim1p and human EB1), and CLIP-170 (human), which reveal diverse tubulin binding interfaces, are reported.

  12. p150Glued may activate and thereby facilitate the recruitment of EB1 to the tips of microtubules to regulate their dynamics.

  13. EB1-tubulin interactions are mediated in part by the same tubulin acidic tails utilized by other MAPs

  14. MAPRE2 is highly expressed in pancreatic cancer cells, and seems to be involved in perineural invasion

Mouse (Murine) Microtubule-Associated Protein, RP/EB Family, Member 2 (MAPRE2) interaction partners

  1. Knockdown of HAX1 and EB2 in skin epidermal cells stabilizes focal adhesions and impairs epidermal migration.

  2. Thus, we suggest that EB1 could complement MAP1B function during neural development.

Microtubule-Associated Protein, RP/EB Family, Member 2 (MAPRE2) Antigen Profile

Protein Summary

The protein encoded by this gene shares significant homology to the adenomatous polyposis coli (APC) protein-binding EB1 gene family. This protein is a microtubule-associated protein that is necessary for spindle symmetry during mitosis. It is thought to play a role in the tumorigenesis of colorectal cancers and the proliferative control of normal cells. Alternative splicing of this gene results in multiple transcript variants.

Gene names and symbols associated with MAPRE2

  • microtubule associated protein RP/EB family member 2 (MAPRE2) antibody
  • microtubule-associated protein, RP/EB family, member 2 (Mapre2) antibody
  • microtubule associated protein RP/EB family member 2 S homeolog (mapre2.S) antibody
  • AI314113 antibody
  • C820009F03Rik antibody
  • D18Abb1e antibody
  • DKFZp459O163 antibody
  • EB1 antibody
  • EB2 antibody
  • MAPRE2 antibody
  • mapre2-A antibody
  • RP1 antibody

Protein level used designations for MAPRE2

microtubule-associated protein, RP/EB family, member 2 , Microtubule-associated protein RP/EB family member 2 , APC-binding protein EB1 , APC-binding protein EB2 , T-cell activation protein, EB1 family , end-binding protein 2 , microtubule-associated protein RP/EB family member 2 , T-cell activation protein, EB1 family, member 2

GENE ID SPECIES
455369 Pan troglodytes
100173979 Pongo abelii
100227855 Taeniopygia guttata
10982 Homo sapiens
212307 Mus musculus
679221 Rattus norvegicus
510159 Bos taurus
421105 Gallus gallus
490487 Canis lupus familiaris
373805 Xenopus laevis
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