Migration and Invasion Inhibitory Protein Proteins (MIIP)

MIIP encodes a protein that interacts with the oncogene protein insulin-like growth factor binding protein 2 and may function as an inhibitor of cell migration and invasion. Additionally we are shipping MIIP Antibodies (38) and MIIP Kits (6) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MIIP 60672 Q5JXC2
MIIP 28010 A2A7Y5
Rat MIIP MIIP 298643 Q6AYH0
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Top MIIP Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$6,869.04
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$6,869.04
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see Available
$814.00
Details
Wheat germ Human GST tag 2 μg Log in to see 11 to 12 Days
$338.33
Details

MIIP Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)

More Proteins for Migration and Invasion Inhibitory Protein (MIIP) Interaction Partners

Human Migration and Invasion Inhibitory Protein (MIIP) interaction partners

  1. Data show that protein kinase C epsilon (PKCepsilon (show PRKCE Proteins)) phosphorylates migration and invasion inhibitory protein (MIIP) at Ser303 and promotes its binding to RelA/p65 (show NFkBP65 Proteins), facilitating colorectal cancer metastasis.

  2. MIIP may function as a tumor suppressor gene for endometrial carcinoma. MIIP attenuates Rac1 signaling through a protein interaction network, and loss of this regulator may contribute to EC metastasis.

  3. MIIP haploinsufficiency induces chromosomal instability and promotes tumour progression in colorectal cancer.

  4. MIIP expression in esophageal squamous-cell carcinoma tissues was increased significantly in comparison with the paired paracancerous normal epithelia and was associated with cell differentiation. Patients with low MIIP expression had improved overall and disease-free survival. MIIP expression was an independent prognostic factor in ESCC OS and DFS (show FST Proteins).

  5. MIIP attenuates mitotic transition and increases mitotic catastrophe, thereby inhibiting glioma development and progression.

  6. Data show a novel mechanism by which IIp45 inhibits cell motility through inhibition of HDAC6 (show HDAC6 Proteins).

  7. Results suggest MIIP K167E as a functional genetic marker of breast cancer development and prognosis.

  8. identified a gene, invasion inhibitory protein 45 (IIp45), whose protein product bound to IGFBP-2 (show IGFBP2 Proteins) through the thyroglobulin (show TG Proteins)-RGD region of the C terminus of IGFBP-2 (show IGFBP2 Proteins)

  9. IIp45 gene is inactivated by a tumor-specific alternative splicing that generates an aberrant and unstable IIp45 isoform in infiltrative gliomas.

MIIP Protein Profile

Protein Summary

This gene encodes a protein that interacts with the oncogene protein insulin-like growth factor binding protein 2 and may function as an inhibitor of cell migration and invasion. This protein also interacts with the cell division protein 20 and may be involved in regulating mitotic progression. This protein may function as a tumor suppressor by inhibiting the growth or certain cancers.

Gene names and symbols associated with MIIP

  • migration and invasion inhibitory protein (MIIP)
  • migration and invasion inhibitory protein (Miip)
  • AA553001 protein
  • AI853621 protein
  • D4Wsu114e protein
  • Iip45 protein

Protein level used designations for MIIP

IGFBP2-binding protein , invasion-inhibitory protein 45 , migration and invasion-inhibitory protein , invasion inhibitory protein 45 , IGFBP-2-Binding Protein, IIp45

GENE ID SPECIES
60672 Homo sapiens
608204 Canis lupus familiaris
614193 Bos taurus
28010 Mus musculus
298643 Rattus norvegicus
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